HitPredict

Interactor 1: TBB3 (Q13509)
Tubulin beta-3 chain (Tubulin beta-4 chain) (Tubulin beta-III)
Gene: TUBB3

Interactor 2: KLK6 (Q92876)
Kallikrein-6 (EC 3.4.21.-) (Neurosin) (Protease M) (SP59) (Serine protease 18) (Serine protease 9) (Zyme)
Gene: KLK6

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	28514442
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0045171 - intercellular bridge
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 450 Hs			1 244
+	Hs
		428722 TBB3_HUMAN (1-450): 0: 723: 100.00		TRY2_HUMAN (21-243): 1.31e-111: 322: 43.56
+	Hs
		1037427 TBB3_HUMAN (1-450): 0: 723: 100.00		KLK11_HUMAN (19-242): 2.29e-105: 307: 44.78
+	Hs
		1037390 TBB3_HUMAN (1-450): 0: 723: 100.00		TMPS5_HUMAN (5-243): 1.7e-95: 288: 31.64
+	Hs
		1037451 TBB3_HUMAN (1-450): 0: 723: 100.00		KLK5_HUMAN (17-243): 4.47e-96: 284: 45.02
+	Hs
		420746 TBB8_HUMAN (1-427): 0: 705: 87.59		KLK1_HUMAN (2-242): 3.7e-103: 301: 37.11
+	Hs
		1114231 TBB8_HUMAN (1-427): 0: 705: 87.59		KLK15_HUMAN (12-242): 4.73e-103: 300: 44.03
+	Hs
		1114233 TBB8_HUMAN (1-427): 0: 705: 87.59		TMPS5_HUMAN (5-243): 1.7e-95: 288: 31.64
+	Hs
		428427 TBB5_HUMAN (1-429): 0: 704: 93.94		TMPS5_HUMAN (5-243): 1.7e-95: 288: 31.64
+	Hs
		933971 TBB4B_HUMAN (1-427): 0: 703: 93.91		TMPS5_HUMAN (5-243): 1.7e-95: 288: 31.64
+	Hs
		1114269 TBB8_HUMAN (1-427): 0: 705: 87.59		KLK5_HUMAN (17-243): 4.47e-96: 284: 45.02
+	Hs
		1046575 TBB2A_HUMAN (1-430): 0: 700: 93.49		TMPS5_HUMAN (5-243): 1.7e-95: 288: 31.64
+	Hs
		1312808 TBB6_HUMAN (1-446): 0: 700: 92.38		TMPS5_HUMAN (5-243): 1.7e-95: 288: 31.64
+	Hs
		428515 TBB5_HUMAN (1-429): 0: 704: 93.94		KLK5_HUMAN (17-243): 4.47e-96: 284: 45.02
+	Hs
		381298 TBB4A_HUMAN (1-427): 0: 699: 93.21		TMPS5_HUMAN (5-243): 1.7e-95: 288: 31.64
+	Hs
		934035 TBB4B_HUMAN (1-427): 0: 703: 93.91		KLK5_HUMAN (17-243): 4.47e-96: 284: 45.02
+	Hs
		1046624 TBB2A_HUMAN (1-430): 0: 700: 93.49		KLK5_HUMAN (17-243): 4.47e-96: 284: 45.02
+	Hs
		1312839 TBB6_HUMAN (1-446): 0: 700: 92.38		KLK5_HUMAN (17-243): 4.47e-96: 284: 45.02
+	Hs
		381216 TBB4A_HUMAN (1-427): 0: 699: 93.21		PRSS8_HUMAN (12-241): 1.32e-94: 282: 34.13
+	Mm
		371765 TBB4B_MOUSE (1-427): 0: 703: 93.91		CFAD_MOUSE (5-240): 1.65e-92: 274: 35.37
+	Hs
		836354 TBB3_HUMAN (1-450): 0: 723: 100.00		GRAK_HUMAN (21-241): 5.95e-41: 142: 37.18