HitPredict

Interactor 1: PRP4K (Q13523)
Serine/threonine-protein kinase PRP4 homolog (EC 2.7.11.1) (PRP4 kinase) (PRP4 pre-mRNA-processing factor 4 homolog)
Gene: PRP4K

Interactor 2: BRD7 (Q9NPI1)
Bromodomain-containing protein 7 (75 kDa bromodomain protein) (Protein CELTIX-1)
Gene: BRD7

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30940648
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000776 - kinetochore GO:0005634 - nucleus GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1007 Hs			1 651
+	Hs
		998665 PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		631422 PRP4K_HUMAN (1-1007): 1.03e-174: 538: 100.00		BRD2_HUMAN (115-424): 3.01e-33: 138: 15.39
+	Hs
		999150 CDK12_HUMAN (31-1005): 5.97e-121: 405: 15.92		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		566375 KPCA_HUMAN (486-978): 6.58e-123: 391: 15.94		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		408611 KPCB_HUMAN (486-990): 2.48e-122: 390: 15.01		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		414892 CDK1_HUMAN (684-1005): 4.59e-124: 381: 25.00		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		999248 DYR1B_HUMAN (618-1005): 4.81e-119: 380: 30.25		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		1270845 DYR1B_HUMAN (618-1005): 4.81e-119: 380: 30.25		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		625393 CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		625532 CDK2_HUMAN (684-955): 5.29e-121: 373: 23.45		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Sc
		565752 PHO85_YEAST (686-1005): 4.97e-117: 363: 27.74		GCN5_YEAST (119-235): 2.37e-36: 143: 29.92
+	Sc
		565790 PHO85_YEAST (686-1005): 4.97e-117: 363: 27.74		BDF2_YEAST (7-357): 7.67e-35: 142: 14.25
+	Sc
		339866 CDK1_YEAST (686-1005): 2.59e-111: 347: 28.27		BDF2_YEAST (7-357): 7.67e-35: 142: 14.25
+	Hs
		319188 DYR1A_HUMAN (677-1005): 2.55e-37: 152: 32.65		BRD1_HUMAN (22-393): 1.28e-54: 203: 20.05
+	Hs
		999086 HIPK2_HUMAN (665-1003): 1.49e-39: 161: 32.59		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		1270794 HIPK3_HUMAN (665-1006): 5.03e-40: 163: 31.77		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		1270792 HIPK2_HUMAN (665-1003): 1.49e-39: 161: 32.59		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		998682 DYR1A_HUMAN (677-1005): 2.55e-37: 152: 32.65		EP300_HUMAN (42-251): 3.1e-41: 164: 22.02
+	Hs
		1206218 HIPK1_HUMAN (671-1003): 1.89e-38: 157: 33.15		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11
+	Hs
		1044010 DYR1A_HUMAN (677-1005): 2.55e-37: 152: 32.65		CBP_HUMAN (25-238): 1.58e-39: 158: 23.11