Interactor 1: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1
Interactor 2: RIPK1 (Q13546)
Receptor-interacting serine/threonine-protein kinase 1 (EC 2.7.11.1) (Cell death protein RIP) (Receptor-interacting protein 1) (RIP-1)
Gene: RIPK1
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.95 | 1.00 | 0.975 |
The method score is based on:
Property | Details |
---|---|
Experiments | 25416956, 27045108, 32296183, 31980649, 15001576, 23473668, unassigned1304, 14743216, 22817896 |
Identification Methods | two hybrid, enzymatic study, affinity chromatography technology, two hybrid array, protein kinase assay, validated two hybrid, two hybrid prey pooling approach, tandem affinity purification, molecular sieving, electron microscopy and 2 others
more... |
Interaction Type | direct interaction, physical association, phosphorylation reaction |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Death~Death, PK_Tyr_Ser-Thr~PK_Tyr_Ser-Thr |
Common GO terms | GO:0001934 - positive regulation of protein phosphorylation GO:0004672 - protein kinase activity GO:0004674 - protein serine/threonine kinase activity GO:0004706 - JUN kinase kinase kinase activity GO:0005123 - death receptor binding and 62 others more... |
Homologous interactions | 17 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024