Protein: RHEB
GTP-binding protein Rheb homolog (EC 3.6.5.-)

Gene: RHEB
Organism: Drosophila melanogaster
Interactions: 96
UniProt ID: Q9VND8

Gene Ontology (top 5):
GO:0000082 - G1/S transition of mitotic cell cycle
GO:0000139 - Golgi membrane
GO:0002052 - positive regulation of neuroblast proliferation
GO:0003924 - GTPase activity
GO:0005525 - GTP binding

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1475137

TCTP
Translationally-controlled tumor protein homolog

3

1

Small-scale

0.675

High

120379

M9PD17
Gigas, isoform B

1

11

High-throughput

0.618

High

1470155

ANKHM
Ankyrin repeat and KH domain-containing protein mask

1

3

High-throughput

0.618

High

1474107

Q9VFT4
AT27578p

1

7

High-throughput

0.618

High

1474145

Q9VFV9
DnaJ-like-2, isoform A

1

4

High-throughput

0.618

High

1474980

IPO9
Importin-9

1

2

High-throughput

0.618

High

554100

TCPA
T-complex protein 1 subunit alpha

2

9

Small-scale

0.584

High

1019924

1433E
14-3-3 protein epsilon

2

3

Small-scale

0.584

High

304152

RAB7
Ras-related protein Rab7

1

18

High-throughput

0.575

High

1482598

Q9VW83
Gigas, isoform A

1

11

High-throughput

0.575

High

1470234

Q9VCC9
LD23779p

1

18

High-throughput

0.536

High

119620

M9PAY7
Pi3K21B, isoform C

1

19

High-throughput

0.479

High

612409

ACTN
Alpha-actinin, sarcomeric

1

5

High-throughput

0.479

High

709573

1433Z
14-3-3 protein zeta

1

8

Small-scale

0.479

High

823799

SQH
Myosin regulatory light chain sqh

1

2

High-throughput

0.479

High

834828

IF2A
Eukaryotic translation initiation factor 2 subunit 1

1

2

High-throughput

0.479

High

875132

CAPZB
F-actin-capping protein subunit beta

1

3

High-throughput

0.479

High

920998

ACT3
Actin-57B

1

4

High-throughput

0.479

High

1038252

IF4A
Eukaryotic initiation factor 4A

1

1

High-throughput

0.479

High

1172949

IF2G
Eukaryotic translation initiation factor 2 subunit 3

1

2

High-throughput

0.479

High

1262242

EIF3M
Eukaryotic translation initiation factor 3 subunit M

1

1

High-throughput

0.479

High

1267736

Q7KMQ0
26S proteasome regulatory subunit 7

1

7

High-throughput

0.479

High

1267969

TERA
Transitional endoplasmic reticulum ATPase TER94

1

7

High-throughput

0.479

High

1268043

Q7KN75
Dodeca-satellite-binding protein 1, isoform A

1

5

High-throughput

0.479

High

1378574

FOXO
Forkhead box protein O

1

1

High-throughput

0.479

High

1404027

MYSN
Myosin heavy chain, non-muscle

1

1

High-throughput

0.479

High

1464877

Q9V405
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.479

High

1466764

Q9V9Q4
LD43819p

1

3

High-throughput

0.479

High

1472781

Q9VEH0
Aluminum tubes, isoform A

1

18

High-throughput

0.479

High

1476293

Q9VHL2
T-complex protein 1 subunit eta

1

7

High-throughput

0.479

High

1477465

DDX47
ATP-dependent RNA helicase DDX47

1

3

High-throughput

0.479

High

1479259

Q9VK69
T-complex protein 1 subunit delta

1

6

Small-scale

0.479

High

1482297

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

5

High-throughput

0.479

High

1482589

GOLP3
Golgi phosphoprotein 3 homolog sauron

1

3

Small-scale

0.479

High

1482595

AGO2
Protein argonaute-2

1

1

High-throughput

0.479

High

1482599

Q9W1G7
LD21576p

1

1

High-throughput

0.479

High

1482605

Q9W4M7
Twenty-four, isoform B

1

1

High-throughput

0.479

High

1482592

Q9VS51
Cln7, isoform A

1

4

Small-scale

0.470

High

118629

M9NF14
IGF-II mRNA-binding protein, isoform L

1

0

High-throughput

0.458

High

618793

DDX17
ATP-dependent RNA helicase p62

1

0

High-throughput

0.458

High

1345671

RS23
Small ribosomal subunit protein uS12

1

0

High-throughput

0.458

High

1482538

ORCO
Odorant receptor coreceptor

1

0

Small-scale

0.458

High

1482594

EIF3L
Eukaryotic translation initiation factor 3 subunit L

1

0

High-throughput

0.458

High

1482607

LSG1
Large subunit GTPase 1 homolog

1

0

High-throughput

0.458

High

1343688

Q8SXC0
GH10306p

1

1

High-throughput

0.445

High

1476801

ARL8
ADP-ribosylation factor-like protein 8

1

20

High-throughput

0.445

High

1482597

Q9VVL5
FI11325p

1

1

High-throughput

0.445

High

145788

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.437

High

534488

ACT1
Actin-5C

1

4

High-throughput

0.437

High

715379

BIP
Endoplasmic reticulum chaperone BiP

1

13

High-throughput

0.437

High

715410

HSP7E
Heat shock 70 kDa protein cognate 5

1

16

High-throughput

0.437

High

856480

RL7A
Large ribosomal subunit protein eL8

1

1

High-throughput

0.437

High

1044934

NONA
Protein no-on-transient A

1

1

High-throughput

0.437

High

1052485

ATPB
ATP synthase subunit beta, mitochondrial

1

5

High-throughput

0.437

High

1064246

SQD
RNA-binding protein squid

1

3

High-throughput

0.437

High

1173964

ISWI
Chromatin-remodeling complex ATPase chain Iswi

1

3

High-throughput

0.437

High

1267273

Q7KKI0
T-complex protein 1 subunit epsilon

1

7

High-throughput

0.437

High

1344558

Q8SYL1
Glutamate-rich WD repeat-containing protein 1

1

6

High-throughput

0.437

High

1463384

Q9V3E7
LD24793p

1

2

High-throughput

0.437

High

1467543

RS7
Small ribosomal subunit protein eS7

1

1

High-throughput

0.437

High

1469789

Q9VBX3
Vig2, isoform B

1

2

High-throughput

0.437

High

1480790

Y3096
Ribosomal L1 domain-containing protein CG13096

1

5

High-throughput

0.437

High

1481528

Q9VM61
Uncharacterized protein, isoform A

1

1

High-throughput

0.437

High

1482553

Q9VNB9
Large ribosomal subunit protein eL33

1

2

High-throughput

0.437

High

1482590

Q9VQL7
Fatty acid synthase

1

3

High-throughput

0.437

High

1482593

R10AB
Large ribosomal subunit protein uL1

1

1

High-throughput

0.437

High

1482596

Q9VUR2
LD31322p

1

2

High-throughput

0.437

High

1482602

CAPZA
F-actin-capping protein subunit alpha

1

1

High-throughput

0.437

High

1482606

NSUN2
tRNA

1

1

High-throughput

0.437

High

1482608

X2JE07
Uncharacterized protein, isoform D

1

1

High-throughput

0.437

High

762729

UBE2N
Ubiquitin-conjugating enzyme E2 N

1

0

High-throughput

0.426

High

98455

F0JAG2
MIP27703p

1

0

High-throughput

0.249

Low

122116

M9PHL6
Bifocal, isoform E

1

0

High-throughput

0.249

Low

232153

O44434
QKR58E-3

1

0

High-throughput

0.249

Low

235140

O46307
EG:8D8.4 protein

1

0

High-throughput

0.249

Low

262635

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.249

Low

710955

RS6
Small ribosomal subunit protein eS6

1

0

High-throughput

0.249

Low

832265

RL13
Large ribosomal subunit protein eL13

1

0

High-throughput

0.249

Low

885135

RL36
Large ribosomal subunit protein eL36

1

0

High-throughput

0.249

Low

898304

RL9
Large ribosomal subunit protein uL6

1

0

High-throughput

0.249

Low

939003

RL14
Large ribosomal subunit protein eL14

1

0

High-throughput

0.249

Low

1172904

RS5A
Small ribosomal subunit protein uS7A

1

0

High-throughput

0.249

Low

1378038

Q95SM8
GH13859p

1

0

High-throughput

0.249

Low

1463430

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.249

Low

1467103

Q9V9W2
Large ribosomal subunit protein eL6

1

0

High-throughput

0.249

Low

1469342

Q9VBN5
60S ribosomal protein L27

1

0

High-throughput

0.249

Low

1473467

Q9VF05
RE18415p

1

0

High-throughput

0.249

Low

1477448

NOC2L
Nucleolar complex protein 2

1

0

High-throughput

0.249

Low

1477987

Q9VJ19
Large ribosomal subunit protein eL30

1

0

High-throughput

0.249

Low

1482591

RL18
Large ribosomal subunit protein eL18

1

0

High-throughput

0.249

Low

1482600

FBRL
rRNA 2'-O-methyltransferase fibrillarin

1

0

High-throughput

0.249

Low

1482601

RTF1
RNA polymerase-associated protein Rtf1

1

0

High-throughput

0.249

Low

1482603

Q9W394
Activator of basal transcription 1

1

0

High-throughput

0.249

Low

1482604

RL17
Large ribosomal subunit protein uL22

1

0

High-throughput

0.249

Low

553699

APT
Adenine phosphoribosyltransferase

1

0

High-throughput

0.232

Low

1470470

Q9VCJ6
AT18965p

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025