HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: RBCC1 (Q8TDY2)
RB1-inducible coiled-coil protein 1 (FAK family kinase-interacting protein of 200 kDa) (FIP200)
Gene: RB1CC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.66	0.60	0.633

Property	Details
Experiments	31980649, 34709266, unassigned2173
Identification Methods	affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 1594
+	Hs
		1038680 HDAC1_HUMAN (1-482): 0: 668: 100.00		CP250_HUMAN (505-1593): 2.27e-40: 166: 10.73
+	Hs
		528410 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH8_HUMAN (131-1077): 4.17e-32: 139: 8.26
+	Hs
		522611 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH7_HUMAN (102-1110): 1.88e-30: 133: 9.54
+	Hs
		1038380 HDAC1_HUMAN (1-482): 0: 668: 100.00		GOGB1_HUMAN (584-1592): 5.4e-28: 126: 9.38
+	Hs
		724813 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH9_HUMAN (1067-1588): 1.89e-22: 107: 11.48
+	Hs
		724945 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH9_HUMAN (1067-1588): 1.89e-22: 107: 11.48
+	Hs
		1038853 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH4_HUMAN (986-1592): 1.94e-18: 94.5: 12.03
+	Hs
		1038808 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH2_HUMAN (1208-1592): 1.51e-15: 84.9: 11.99
+	Hs
		725212 HDAC2_HUMAN (1-478): 0: 666: 85.92		MYH10_HUMAN (1179-1592): 1.19e-15: 85.3: 10.15
+	Hs
		148775 HDAC1_HUMAN (1-482): 0: 668: 100.00		CTRO_HUMAN (605-1125): 1.59e-12: 75.2: 10.62
+	Hs
		522547 HDAC1_HUMAN (1-482): 0: 668: 100.00		MYH1_HUMAN (1197-1592): 1.61e-12: 74.9: 14.25
+	Hs
		1038397 HDAC1_HUMAN (1-482): 0: 668: 100.00		PLEC_HUMAN (101-713): 3.96e-12: 74.1: 7.02
+	Hs
		149134 HDAC2_HUMAN (1-478): 0: 666: 85.92		CTRO_HUMAN (605-1125): 1.59e-12: 75.2: 10.62
+	Hs
		1038672 HDAC1_HUMAN (1-482): 0: 668: 100.00		AKAP9_HUMAN (793-1458): 2.62e-09: 64.5: 14.18
+	Hs
		177316 HDAC3_HUMAN (9-434): 0: 574: 57.94		GRDN_HUMAN (907-1591): 2.18e-17: 91.1: 10.32
+	Mm
		1143175 HDAC6_MOUSE (11-325): 4.35e-103: 334: 25.69		MYH10_MOUSE (1179-1592): 3.09e-15: 84.1: 9.66
+	Hs
		725053 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH9_HUMAN (1067-1588): 1.89e-22: 107: 11.48
+	Hs
		725261 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH10_HUMAN (1179-1592): 1.19e-15: 85.3: 10.15
+	Hs
		551864 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		DESP_HUMAN (899-1502): 4.19e-13: 77.2: 12.32
+	Hs
		728525 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		MYH11_HUMAN (1288-1592): 1.18e-09: 65.6: 10.16