Protein: TIM50
Mitochondrial import inner membrane translocase subunit TIM50

Gene: TIM50
Organism: Saccharomyces cerevisiae S288C
Interactions: 99
UniProt ID: Q02776

Gene Ontology (top 5):
GO:0005739 - mitochondrion
GO:0005743 - mitochondrial inner membrane
GO:0005744 - TIM23 mitochondrial import inner membrane translocase complex
GO:0006886 - intracellular protein transport
GO:0030150 - protein import into mitochondrial matrix

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1038548

TIM50
Mitochondrial import inner membrane translocase subunit TIM50

5

7

Small-scale

0.914

High

746924

TIM23
Mitochondrial import inner membrane translocase subunit TIM23

42

3

Small-scale

0.771

High

811979

TIM17
Mitochondrial import inner membrane translocase subunit TIM17

10

1

Small-scale

0.752

High

918298

TIM21
Mitochondrial import inner membrane translocase subunit TIM21

10

0

Small-scale

0.724

High

844710

TIM16
Mitochondrial import inner membrane translocase subunit TIM16

5

0

Small-scale

0.681

High

510752

HSP77
Import motor subunit, mitochondrial

3

4

Small-scale

0.646

High

881422

TOM22
Mitochondrial import receptor subunit TOM22

4

0

Small-scale

0.643

High

782197

PAM17
Presequence translocated-associated motor subunit PAM17, mitochondrial

3

0

Small-scale

0.638

High

661821

TOM40
Mitochondrial import receptor subunit TOM40

3

0

Small-scale

0.628

High

358023

CYB2
L-lactate dehydrogenase

3

0

Small-scale

0.613

High

918085

JAC1
J-type co-chaperone JAC1, mitochondrial

3

0

Small-scale

0.613

High

453195

QCR1
Cytochrome b-c1 complex subunit 1, mitochondrial

2

1

Small-scale

0.584

High

1033450

TIM44
Mitochondrial import inner membrane translocase subunit TIM44

2

1

Small-scale

0.584

High

613625

ADT2
ADP,ATP carrier protein 2

2

4

Small-scale

0.571

High

399873

COX4
Cytochrome c oxidase subunit 4, mitochondrial

2

0

Small-scale

0.569

High

465355

UCRI
Cytochrome b-c1 complex subunit Rieske, mitochondrial

2

0

Small-scale

0.559

High

734571

MSS51
Protein MSS51, mitochondrial

2

0

Small-scale

0.559

High

752642

HSP78
Heat shock protein 78, mitochondrial

2

0

High-throughput

0.559

High

781449

MIC60
MICOS complex subunit MIC60

2

0

High-throughput

0.559

High

815708

OXA1
Mitochondrial inner membrane protein OXA1

2

0

Small-scale

0.559

High

1038558

TIM14
Mitochondrial import inner membrane translocase subunit TIM14

2

0

Small-scale

0.559

High

823443

MPM1
Mitochondrial peculiar membrane protein 1

2

0

High-throughput

0.547

High

817935

IMB4
Importin subunit beta-4

2

2

High-throughput

0.521

High

626862

HSP60
Heat shock protein 60, mitochondrial

1

0

Small-scale

0.480

High

452051

TOM70
Mitochondrial import receptor subunit TOM70

1

1

Small-scale

0.479

High

579932

HSC82
ATP-dependent molecular chaperone HSC82

1

1

High-throughput

0.479

High

639053

VPS1
Vacuolar protein sorting-associated protein 1

1

2

High-throughput

0.479

High

647193

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

4

High-throughput

0.479

High

779508

YKT6
Synaptobrevin homolog YKT6

1

1

High-throughput

0.479

High

1038562

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.479

High

638929

CBP3
Protein CBP3, mitochondrial

1

0

High-throughput

0.458

High

736298

RM41
Large ribosomal subunit protein uL23m

1

0

High-throughput

0.458

High

783885

RM04
Large ribosomal subunit protein uL29m

1

0

High-throughput

0.458

High

784126

RM15
Large ribosomal subunit protein mL57

1

0

High-throughput

0.458

High

797640

MBA1
Inner membrane mitoribosome receptor MBA1, mitochondrial

1

0

High-throughput

0.458

High

816093

DLD3
D-2-hydroxyglutarate--pyruvate transhydrogenase DLD3

1

0

Small-scale

0.458

High

818637

FMP10
Uncharacterized mitochondrial membrane protein FMP10

1

0

High-throughput

0.458

High

922875

ATP23
Mitochondrial inner membrane protease ATP23

1

0

High-throughput

0.458

High

1038555

SYRC
Arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.458

High

1038560

YD157
Uncharacterized protein YDL157C, mitochondrial

1

0

Small-scale

0.458

High

1038565

PDP1
[Pyruvate dehydrogenase [acetyl-transferring]]-phosphatase 1, mitochondrial

1

0

High-throughput

0.458

High

527488

HSP72
Heat shock protein SSA2

1

6

High-throughput

0.445

High

536158

ARF1
ADP-ribosylation factor 1

1

1

High-throughput

0.445

High

661681

MPCP
Mitochondrial phosphate carrier protein

1

5

High-throughput

0.445

High

734381

OAC1
Mitochondrial oxaloacetate transport protein

1

6

High-throughput

0.445

High

792746

ETR1
Enoyl-[acyl-carrier-protein] reductase, mitochondrial

1

2

High-throughput

0.445

High

801098

FKS1
1,3-beta-glucan synthase component FKS1

1

1

High-throughput

0.445

High

1038183

IRC15
Increased recombination centers protein 15

1

0

High-throughput

0.438

High

518373

IF4A
ATP-dependent RNA helicase eIF4A

1

1

High-throughput

0.437

High

671043

SIS1
Protein SIS1

1

2

High-throughput

0.437

High

779325

CENPA
Histone H3-like centromeric protein CSE4

1

3

High-throughput

0.437

High

812591

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

1038553

SCC2
Sister chromatid cohesion protein 2

1

3

High-throughput

0.437

High

1038556

IMB1
Importin subunit beta-1

1

3

High-throughput

0.437

High

1038561

MLH3
DNA mismatch repair protein MLH3

1

1

High-throughput

0.437

High

918067

PIB2
Glutamine sensor PIB2

1

0

High-throughput

0.426

High

1028021

ACAC
Acetyl-CoA carboxylase

1

0

High-throughput

0.426

High

737934

HOG1
Mitogen-activated protein kinase HOG1

1

1

High-throughput

0.417

High

792917

ANM1
Protein arginine N-methyltransferase 1

1

2

High-throughput

0.417

High

804030

MED6
Mediator of RNA polymerase II transcription subunit 6

1

1

High-throughput

0.417

High

1038559

DSC3
DSC E3 ubiquitin ligase complex subunit 3

1

1

High-throughput

0.417

High

358315

ADH1
Alcohol dehydrogenase 1

1

1

High-throughput

0.407

High

358419

ADH2
Alcohol dehydrogenase 2

1

1

High-throughput

0.407

High

386830

TBB
Tubulin beta chain

1

3

High-throughput

0.407

High

486289

TBA1
Tubulin alpha-1 chain

1

8

High-throughput

0.407

High

504572

YD14B
Transposon Ty1-DR5 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

504582

YD15B
Transposon Ty1-DR6 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

524914

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.407

High

545983

SSB1
Ribosome-associated molecular chaperone SSB1

1

5

High-throughput

0.407

High

671383

PHO84
Inorganic phosphate transporter PHO84

1

2

High-throughput

0.407

High

701735

URA7
CTP synthase 1

1

1

High-throughput

0.407

High

734187

EF2
Elongation factor 2

1

1

High-throughput

0.407

High

742229

HSP7F
Heat shock protein homolog SSE1

1

7

High-throughput

0.407

High

803661

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.407

High

821031

EIF3I
Eukaryotic translation initiation factor 3 subunit I

1

2

High-throughput

0.407

High

830112

FKS2
1,3-beta-glucan synthase component GSC2

1

1

High-throughput

0.407

High

871444

HLJ1
Protein HLJ1

1

4

High-throughput

0.407

High

917311

INO80
Chromatin-remodeling ATPase INO80

1

1

High-throughput

0.407

High

1038549

YE11B
Transposon Ty1-ER1 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

1038550

YE12B
Transposon Ty1-ER2 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

1038552

YD11B
Transposon Ty1-DR1 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

1038564

YB12B
Transposon Ty1-BR Gag-Pol polyprotein

1

6

High-throughput

0.407

High

1038566

YD12B
Transposon Ty1-DR3 Gag-Pol polyprotein

1

6

High-throughput

0.407

High

1038554

AIM32
Altered inheritance of mitochondria protein 32

1

0

Small-scale

0.261

Low

558842

CAF20
Cap-associated protein CAF20

1

0

High-throughput

0.249

Low

737586

ERG1
Squalene epoxidase ERG1

1

0

High-throughput

0.249

Low

795166

NU170
Nucleoporin NUP170

1

0

High-throughput

0.249

Low

677289

PEX34
Peroxisomal membrane protein PEX34

1

0

High-throughput

0.238

Low

779794

DYHC
Dynein heavy chain, cytoplasmic

1

0

High-throughput

0.238

Low

1038551

YMD8
Putative nucleotide-sugar transporter YMD8

1

0

High-throughput

0.238

Low

1038557

SFH1
Chromatin structure-remodeling complex subunit SFH1

1

0

High-throughput

0.238

Low

1038563

GET3
ATPase GET3

1

0

High-throughput

0.238

Low

452527

PUR2
Bifunctional purine biosynthetic protein ADE5,7 [Includes: Phosphoribosylamine--glycine ligase

1

0

High-throughput

0.232

Low

780817

YKH5
Uncharacterized protein YKL075C

1

0

High-throughput

0.232

Low

802684

YHI0
Putative proline--tRNA ligase YHR020W

1

0

High-throughput

0.232

Low

865047

TCPQ
T-complex protein 1 subunit theta

1

0

High-throughput

0.232

Low

918360

ORM1
Protein ORM1

1

0

High-throughput

0.232

Low

924708

NAF1
H/ACA ribonucleoprotein complex non-core subunit NAF1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025