Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.994

The method score is based on:

Property Details
Experiments 19182791, 26496610, 28514442, 12032298, 12920132, 11804585, 11466315, 11739383, 11564889, 10444591, 9520398, 9150135, 10581039, 26949739, 24981860, 33961781, 35271311, 35235311, 34349018, 19041848 and 18 others

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Identification Methods affinity chromatography technology, biochemical, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation, coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Hist_deacetyl~Hist_deacetyl
Common GO terms GO:0000118 - histone deacetylase complex
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000785 - chromatin
GO:0004407 - histone deacetylase activity
GO:0005634 - nucleus
and 33 others

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Homologous interactions 16

Homologous interactions

Color coding for hit scores

1 482
Hs

1 488
+ Mm
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+ Rn
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+ Dm
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+ At
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Last updated: 15 Jul 2024