Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1
Interactor 2: HDAC2 (Q92769)
Histone deacetylase 2 (HD2) (EC 3.5.1.98) (Protein deacylase HDAC2) (EC 3.5.1.-)
Gene: HDAC2
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
Method score | Annotation score | Interaction score |
---|---|---|
0.98 | 1.00 | 0.994 |
The method score is based on:
Property | Details |
---|---|
Experiments | 19182791, 26496610, 28514442, 12032298, 12920132, 11804585, 11466315, 11739383, 11564889, 10444591, 9520398, 9150135, 10581039, 26949739, 24981860, 33961781, 35271311, 35235311, 34349018, 19041848 and 18 others
more... |
Identification Methods | affinity chromatography technology, biochemical, cross-linking study, anti tag coimmunoprecipitation, tandem affinity purification, anti bait coimmunoprecipitation, coimmunoprecipitation |
Interaction Type | physical association, association |
The annotation score is based on:
Property | Details |
---|---|
Interacting Pfam domains | Hist_deacetyl~Hist_deacetyl |
Common GO terms | GO:0000118 - histone deacetylase complex GO:0000122 - negative regulation of transcription by RNA polymerase II GO:0000785 - chromatin GO:0004407 - histone deacetylase activity GO:0005634 - nucleus and 33 others more... |
Homologous interactions | 16 |
Homologous interactions
Color coding for hit scores
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024