Protein: TCB3
Tricalbin-3

Gene: TCB3
Organism: Saccharomyces cerevisiae S288C
Interactions: 119
UniProt ID: Q03640

Gene Ontology (top 5):
GO:0005543 - phospholipid binding
GO:0005544 - calcium-dependent phospholipid binding
GO:0005739 - mitochondrion
GO:0005783 - endoplasmic reticulum
GO:0005789 - endoplasmic reticulum membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1043487

TCB1
Tricalbin-1

3

17

Small-scale

0.850

High

871011

TCB2
Tricalbin-2

3

16

Small-scale

0.839

High

1043466

TCB3
Tricalbin-3

1

15

High-throughput

0.698

High

825143

QDR2
Quinidine resistance protein 2

2

10

High-throughput

0.613

High

1043479

FLC1
Flavin carrier protein 1

2

2

High-throughput

0.613

High

813751

FLC2
Flavin carrier protein 2

2

2

High-throughput

0.588

High

1043474

YL413
Cell membrane protein YLR413W

2

0

High-throughput

0.587

High

918285

YG1I
Uncharacterized membrane protein YGR026W

2

2

High-throughput

0.571

High

925017

APJ1
J domain-containing protein APJ1

2

5

High-throughput

0.571

High

812293

ATC3
Phospholipid-transporting ATPase DRS2

1

2

Small-scale

0.552

High

625918

HNM1
Choline transporter

1

5

High-throughput

0.541

High

660514

HXT2
High-affinity glucose transporter HXT2

1

4

High-throughput

0.541

High

720849

ITR1
Myo-inositol transporter 1

1

4

High-throughput

0.541

High

737247

HXT1
Low-affinity glucose transporter HXT1

1

4

High-throughput

0.541

High

740364

SNQ2
Protein SNQ2

1

1

High-throughput

0.541

High

802047

HXT5
Probable glucose transporter HXT5

1

4

High-throughput

0.541

High

803463

OSH7
Oxysterol-binding protein homolog 7

1

5

High-throughput

0.541

High

821803

MEP1
Ammonium transporter MEP1

1

3

High-throughput

0.541

High

894366

MUP1
High-affinity methionine permease

1

6

High-throughput

0.541

High

918553

VHT1
Vitamin H transporter

1

4

High-throughput

0.541

High

919319

TPO2
Polyamine transporter 2

1

9

High-throughput

0.541

High

920733

DIP5
Dicarboxylic amino acid permease

1

3

High-throughput

0.541

High

923760

WSC2
Cell wall integrity and stress response component 2

1

3

High-throughput

0.541

High

1038591

PDR12
ATP-dependent permease PDR12

1

1

High-throughput

0.541

High

1043472

TPO3
Polyamine transporter 3

1

9

High-throughput

0.541

High

1043476

TPO1
Polyamine transporter 1

1

9

High-throughput

0.541

High

1043482

WSC3
Cell wall integrity and stress response component 3

1

1

High-throughput

0.541

High

1043484

PST2
Protoplast secreted protein 2

1

1

High-throughput

0.541

High

836328

BNI1
Protein BNI1

1

2

High-throughput

0.536

High

1030564

UBP3
Ubiquitin carboxyl-terminal hydrolase 3

1

4

High-throughput

0.536

High

826787

DSN1
Kinetochore-associated protein DSN1

2

1

High-throughput

0.533

High

439542

PIS
CDP-diacylglycerol--inositol 3-phosphatidyltransferase

1

0

High-throughput

0.518

High

678051

HSP30
30 kDa heat shock protein

1

0

High-throughput

0.518

High

736590

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.518

High

752070

DUR3
Urea active transporter

1

0

High-throughput

0.518

High

776742

SFK1
Protein SFK1

1

0

High-throughput

0.518

High

779879

MID2
Cell wall integrity sensor MID2

1

0

High-throughput

0.518

High

818441

FTR1
Plasma membrane iron permease

1

0

High-throughput

0.518

High

916815

YOR1
Oligomycin resistance ATP-dependent permease YOR1

1

0

High-throughput

0.518

High

1043112

RSN1
Uncharacterized protein RSN1

1

0

High-throughput

0.518

High

1043475

FMP45
SUR7 family protein FMP45

1

0

High-throughput

0.518

High

1043488

YB029
UPF0768 protein YBL029C-A

1

0

High-throughput

0.518

High

800915

NCB5R
NADH-cytochrome b5 reductase 1

1

5

High-throughput

0.515

High

863337

SPC1
Signal peptidase complex subunit 1

1

1

High-throughput

0.515

High

365689

PGK
Phosphoglycerate kinase

1

0

High-throughput

0.513

High

923075

FPK1
Flippase kinase 1

1

6

Small-scale

0.501

High

796282

RFS1
Protein RFS1

1

1

High-throughput

0.494

High

917963

SDS23
Protein SDS23

1

1

High-throughput

0.494

High

439414

PDC1
Pyruvate decarboxylase isozyme 1

1

2

High-throughput

0.489

High

531868

RL4A
Large ribosomal subunit protein uL4A

1

1

High-throughput

0.489

High

885074

RL4B
Large ribosomal subunit protein uL4B

1

1

High-throughput

0.489

High

744397

ATC5
Phospholipid-transporting ATPase DNF1

1

3

Small-scale

0.481

High

438765

SC160
Protein SCP160

1

3

High-throughput

0.479

High

510780

HSP77
Import motor subunit, mitochondrial

1

8

High-throughput

0.479

High

569417

DPM1
Dolichol-phosphate mannosyltransferase

1

1

Small-scale

0.479

High

647200

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

1

High-throughput

0.479

High

680015

CDC48
Cell division control protein 48

1

3

High-throughput

0.479

High

735860

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

2

Small-scale

0.479

High

818190

SCS2
Vesicle-associated membrane protein-associated protein SCS2

1

7

Small-scale

0.479

High

824779

MLP2
Protein MLP2

1

1

High-throughput

0.479

High

844593

UTP10
U3 small nucleolar RNA-associated protein 10

1

2

High-throughput

0.479

High

850181

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

1

1

High-throughput

0.479

High

1025019

NUM1
Nuclear migration protein NUM1

1

2

High-throughput

0.479

High

925381

SAM50
Sorting assembly machinery 50 kDa subunit

1

0

High-throughput

0.458

High

1042485

PEX29
Peroxisomal membrane protein PEX29

1

0

Small-scale

0.458

High

1043468

DHR1
Probable ATP-dependent RNA helicase DHR1

1

0

High-throughput

0.458

High

1043470

PEX30
Peroxisomal membrane protein PEX30

1

0

Small-scale

0.458

High

920742

MEP3
Ammonium transporter MEP3

1

3

High-throughput

0.457

High

1035278

OSH6
Oxysterol-binding protein homolog 6

1

5

High-throughput

0.457

High

1043483

TPO4
Polyamine transporter 4

1

9

High-throughput

0.457

High

1043486

RTN2
Reticulon-like protein 2

1

8

High-throughput

0.457

High

359337

G3P3
Glyceraldehyde-3-phosphate dehydrogenase 3

1

2

High-throughput

0.445

High

386841

TBB
Tubulin beta chain

1

2

High-throughput

0.445

High

393249

HSP82
ATP-dependent molecular chaperone HSP82

1

5

High-throughput

0.445

High

524991

HSP71
Heat shock protein SSA1

1

6

High-throughput

0.445

High

546087

SSB1
Ribosome-associated molecular chaperone SSB1

1

7

High-throughput

0.445

High

819656

SSB2
Ribosome-associated molecular chaperone SSB2

1

7

High-throughput

0.445

High

533190

GPA2
Guanine nucleotide-binding protein alpha-2 subunit

1

0

High-throughput

0.438

High

646520

RAD53
Serine/threonine-protein kinase RAD53

1

4

High-throughput

0.437

High

671065

SIS1
Protein SIS1

1

5

High-throughput

0.437

High

689121

RL16A
Large ribosomal subunit protein uL13A

1

1

High-throughput

0.437

High

708034

TF2B
Transcription initiation factor IIB

1

1

High-throughput

0.437

High

727284

HS104
Heat shock protein 104

1

2

High-throughput

0.437

High

779335

CENPA
Histone H3-like centromeric protein CSE4

1

5

High-throughput

0.437

High

795185

NU170
Nucleoporin NUP170

1

3

High-throughput

0.437

High

812613

LAA1
AP-1 accessory protein LAA1

1

1

High-throughput

0.437

High

824939

TM108
Protein TMA108

1

2

High-throughput

0.437

High

877892

VATG
V-type proton ATPase subunit G

1

1

High-throughput

0.437

High

918972

PESC
Pescadillo homolog

1

2

High-throughput

0.437

High

963686

H3
Histone H3

1

5

High-throughput

0.437

High

1042214

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.437

High

1043467

SCC2
Sister chromatid cohesion protein 2

1

1

High-throughput

0.437

High

1043480

TMA46
Translation machinery-associated protein 46

1

2

High-throughput

0.437

High

358321

ADH1
Alcohol dehydrogenase 1

1

0

High-throughput

0.426

High

368044

ENO2
Enolase 2

1

0

High-throughput

0.426

High

893211

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.426

High

918366

BUD9
Bud site selection protein 9

1

0

High-throughput

0.426

High

919249

YG3A
Uncharacterized protein YGR130C

1

3

High-throughput

0.417

High

676298

MAS5
Mitochondrial protein import protein MAS5

1

5

High-throughput

0.407

High

1043469

PLM2
Protein PLM2

1

0

High-throughput

0.282

High

1043471

YL326
Uncharacterized membrane protein YLR326W

1

0

High-throughput

0.282

High

383359

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.279

Low

383873

RS17A
Small ribosomal subunit protein eS17A

1

0

High-throughput

0.279

Low

427424

RLA0
Large ribosomal subunit protein uL10

1

0

High-throughput

0.279

Low

1043485

SWM1
Anaphase-promoting complex subunit SWM1

1

0

High-throughput

0.279

Low

623938

MYO2
Myosin-2

1

0

Small-scale

0.251

Low

435326

RS3
Small ribosomal subunit protein uS3

1

0

Small-scale

0.249

Low

513562

RL1A
Large ribosomal subunit protein uL1A

1

0

High-throughput

0.249

Low

797785

AIM4
Altered inheritance of mitochondria protein 4

1

0

High-throughput

0.249

Low

865326

MTNB
Methylthioribulose-1-phosphate dehydratase

1

0

High-throughput

0.249

Low

1043473

URN1
Pre-mRNA-splicing factor URN1

1

0

High-throughput

0.249

Low

1043477

SGO1
Shugoshin

1

0

High-throughput

0.249

Low

1043478

NCBP2
Nuclear cap-binding protein subunit 2

1

0

High-throughput

0.249

Low

592470

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.232

Low

835879

RL10
Large ribosomal subunit protein uL16

1

0

High-throughput

0.232

Low

871557

PFD3
Prefoldin subunit 3

1

0

High-throughput

0.232

Low

912436

PFD6
Prefoldin subunit 6

1

0

High-throughput

0.232

Low

1043481

RL7B
Large ribosomal subunit protein uL30B

1

0

High-throughput

0.232

Low


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Last updated: 11Aug2025