HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: PF21B (Q96EK2)
PHD finger protein 21B
Gene: PHF21B

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.50	0.616

Property	Details
Experiments	24981860, 28514442, 33961781
Identification Methods	affinity chromatography technology, tandem affinity purification, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 482 Hs			1 531
+	Hs
		1038782 HDAC1_HUMAN (1-482): 0: 668: 100.00		KDM5B_HUMAN (79-519): 1.17e-70: 247: 13.09
+	Mm
		140293 HDAC1_MOUSE (1-482): 0: 672: 99.38		KDM5B_MOUSE (79-519): 4.61e-69: 243: 12.90
+	Hs
		666529 HDAC1_HUMAN (1-482): 0: 668: 100.00		KDM5A_HUMAN (79-519): 1.84e-67: 238: 13.58
+	Hs
		782341 HDAC1_HUMAN (1-482): 0: 668: 100.00		KDM5C_HUMAN (78-518): 6.19e-66: 234: 13.45
+	Hs
		170356 HDAC1_HUMAN (1-482): 0: 668: 100.00		TIF1A_HUMAN (5-502): 7.68e-65: 229: 13.45
+	Hs
		170436 HDAC2_HUMAN (1-478): 0: 666: 85.92		TIF1A_HUMAN (5-502): 7.68e-65: 229: 13.45
+	Hs
		1038610 HDAC1_HUMAN (1-482): 0: 668: 100.00		PF21A_HUMAN (41-531): 1.26e-53: 194: 28.84
+	Mm
		56897 HDAC1_MOUSE (1-482): 0: 672: 99.38		CHD5_MOUSE (133-525): 4.09e-48: 182: 15.73
+	Hs
		1038563 HDAC1_HUMAN (1-482): 0: 668: 100.00		CHD5_HUMAN (131-525): 1.02e-42: 165: 15.89
+	Mm
		140296 HDAC1_MOUSE (1-482): 0: 672: 99.38		NSD2_MOUSE (87-515): 3.68e-41: 160: 12.28
+	Hs
		331809 HDAC1_HUMAN (1-482): 0: 668: 100.00		NSD2_HUMAN (87-515): 7.44e-41: 160: 12.72
+	Mm
		140286 HDAC1_MOUSE (1-482): 0: 672: 99.38		CHD4_MOUSE (301-481): 1.85e-37: 149: 20.51
+	Hs
		1038382 HDAC1_HUMAN (1-482): 0: 668: 100.00		CHD4_HUMAN (301-481): 3.03e-37: 149: 20.51
+	Hs
		1038817 HDAC1_HUMAN (1-482): 0: 668: 100.00		ZMYD8_HUMAN (250-449): 2.18e-36: 146: 19.00
+	Hs
		1018465 HDAC1_HUMAN (1-482): 0: 668: 100.00		CHD3_HUMAN (167-481): 8.3e-35: 142: 15.04
+	Hs
		1029390 HDAC1_HUMAN (1-482): 0: 668: 100.00		TIF1B_HUMAN (113-501): 1.53e-33: 137: 16.58
+	Hs
		1017292 HDAC1_HUMAN (1-482): 0: 668: 100.00		BPTF_HUMAN (320-396): 2.31e-14: 78.7: 33.77
+	Hs
		217477 HDAC1_HUMAN (1-482): 0: 668: 100.00		AIRE_HUMAN (351-403): 2.6e-14: 77.6: 41.51
+	Mm
		140269 HDAC1_MOUSE (1-482): 0: 672: 99.38		PHF12_MOUSE (339-405): 7.61e-13: 73.3: 36.23
+	Hs
		1038642 HDAC1_HUMAN (1-482): 0: 668: 100.00		PHF12_HUMAN (337-405): 5.06e-13: 74.1: 35.62