Protein: AIP
AH receptor-interacting protein (AIP) (Aryl-hydrocarbon receptor-interacting protein) (HBV X-associated protein 2) (XAP-2) (Immunophilin homolog ARA9)

Gene: AIP
Organism: Homo sapiens
Interactions: 179
UniProt ID: O00170

Gene Ontology (top 5):
GO:0003713 - transcription coactivator activity
GO:0003755 - peptidyl-prolyl cis-trans isomerase activity
GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

124743

AHR
Aryl hydrocarbon receptor

8

11

Small-scale

0.750

High

124753

CDK9
Cyclin-dependent kinase 9

6

16

High-throughput

0.735

High

124800

ULK3
Serine/threonine-protein kinase ULK3

4

6

High-throughput

0.699

High

124783

TEBP
Prostaglandin E synthase 3

4

10

Small-scale

0.696

High

124722

HS90B
Heat shock protein HSP 90-beta

4

20

Small-scale

0.694

High

124718

HS90A
Heat shock protein HSP 90-alpha

4

20

Small-scale

0.683

High

124708

RAF1
RAF proto-oncogene serine/threonine-protein kinase

3

19

High-throughput

0.656

High

124851

AGO1
Protein argonaute-1

3

13

High-throughput

0.650

High

124821

IRF7
Interferon regulatory factor 7

2

5

Small-scale

0.639

High

124765

CSK21
Casein kinase II subunit alpha

2

6

High-throughput

0.634

High

124795

PRA17
PRAME family member 17

2

1

High-throughput

0.628

High

124831

PTN18
Tyrosine-protein phosphatase non-receptor type 18

2

3

High-throughput

0.611

High

124720

RET
Proto-oncogene tyrosine-protein kinase receptor Ret

3

19

Small-scale

0.604

High

124816

NEUR4
Sialidase-4

2

0

High-throughput

0.602

High

124719

YES
Tyrosine-protein kinase Yes

2

15

High-throughput

0.601

High

124691

PRKN
E3 ubiquitin-protein ligase parkin

2

6

High-throughput

0.584

High

124693

PRA10
PRAME family member 10

2

1

High-throughput

0.584

High

124707

EGFR
Epidermal growth factor receptor

2

14

Small-scale

0.576

High

124711

ERBB2
Receptor tyrosine-protein kinase erbB-2

2

15

High-throughput

0.576

High

124768

PPARA
Peroxisome proliferator-activated receptor alpha

1

9

Small-scale

0.561

High

124761

HUNK
Hormonally up-regulated neu tumor-associated kinase

1

5

High-throughput

0.541

High

124860

NEMO
NF-kappa-B essential modulator

1

7

High-throughput

0.541

High

124686

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

1

19

High-throughput

0.536

High

124702

UBP19
Ubiquitin carboxyl-terminal hydrolase 19

1

8

High-throughput

0.536

High

124715

FYN
Tyrosine-protein kinase Fyn

1

15

High-throughput

0.536

High

124723

FGR
Tyrosine-protein kinase Fgr

1

15

High-throughput

0.536

High

124725

ARAF
Serine/threonine-protein kinase A-Raf

1

19

High-throughput

0.536

High

124726

KPSH1
Serine/threonine-protein kinase H1

1

12

High-throughput

0.536

High

124727

SRC
Proto-oncogene tyrosine-protein kinase Src

1

15

High-throughput

0.536

High

124731

FER
Tyrosine-protein kinase Fer

1

20

High-throughput

0.536

High

124736

KAPCG
cAMP-dependent protein kinase catalytic subunit gamma

1

20

High-throughput

0.536

High

124747

GRK6
G protein-coupled receptor kinase 6

1

20

High-throughput

0.536

High

124750

CLK3
Dual specificity protein kinase CLK3

1

10

High-throughput

0.536

High

124754

BLK
Tyrosine-protein kinase Blk

1

15

High-throughput

0.536

High

124755

IRAK1
Interleukin-1 receptor-associated kinase 1

1

4

High-throughput

0.536

High

124756

PRKX
cAMP-dependent protein kinase catalytic subunit PRKX

1

19

High-throughput

0.536

High

124774

ILK
Scaffold protein ILK

1

12

High-throughput

0.536

High

124775

PDE7A
High affinity 3',5'-cyclic-AMP phosphodiesterase 7A

1

7

High-throughput

0.536

High

124776

CDK13
Cyclin-dependent kinase 13

1

14

High-throughput

0.536

High

124780

PDE3A
cGMP-inhibited 3',5'-cyclic phosphodiesterase 3A

1

7

High-throughput

0.536

High

124784

CDC37
Hsp90 co-chaperone Cdc37

1

12

High-throughput

0.536

High

124797

NADE
Glutamine-dependent NAD(+) synthetase

1

5

High-throughput

0.536

High

124799

PKN3
Serine/threonine-protein kinase N3

1

8

High-throughput

0.536

High

124815

DNJB3
DnaJ homolog subfamily B member 3

1

17

High-throughput

0.536

High

124822

RAB24
Ras-related protein Rab-24

1

2

High-throughput

0.536

High

124824

SGK3
Serine/threonine-protein kinase Sgk3

1

11

High-throughput

0.536

High

124826

AURKB
Aurora kinase B

1

16

High-throughput

0.536

High

124830

PSKH2
Serine/threonine-protein kinase H2

1

15

High-throughput

0.536

High

124838

PLK3
Serine/threonine-protein kinase PLK3

1

4

High-throughput

0.536

High

124842

SGK2
Serine/threonine-protein kinase Sgk2

1

11

High-throughput

0.536

High

124843

DYRK4
Dual specificity tyrosine-phosphorylation-regulated kinase 4

1

12

High-throughput

0.536

High

124845

KTU
Protein kintoun

1

1

High-throughput

0.536

High

124852

TAOK2
Serine/threonine-protein kinase TAO2

1

5

High-throughput

0.536

High

124855

SGT1
Protein SGT1 homolog

1

20

High-throughput

0.536

High

124684

PDE2A
cGMP-dependent 3',5'-cyclic phosphodiesterase

1

5

Small-scale

0.529

High

124779

GNA13
Guanine nucleotide-binding protein subunit alpha-13

1

6

Small-scale

0.527

High

124778

BTG3
Protein BTG3

1

0

High-throughput

0.518

High

124828

LCOR
Ligand-dependent corepressor

1

0

High-throughput

0.518

High

124788

KHDC1
KH homology domain-containing protein 1

1

0

High-throughput

0.513

High

124817

S39A7
Zinc transporter SLC39A7

1

0

High-throughput

0.513

High

124844

SHFL
Shiftless antiviral inhibitor of ribosomal frameshifting protein

1

0

High-throughput

0.513

High

124856

SAMH1
Deoxynucleoside triphosphate triphosphohydrolase SAMHD1

1

0

High-throughput

0.513

High

124793

TNI3K
Serine/threonine-protein kinase TNNI3K

1

12

Small-scale

0.508

High

124738

ARNT
Aryl hydrocarbon receptor nuclear translocator

1

11

Small-scale

0.501

High

124741

STIP1
Stress-induced-phosphoprotein 1

1

19

Small-scale

0.501

High

124751

GNAQ
Guanine nucleotide-binding protein G(q) subunit alpha

1

6

Small-scale

0.501

High

124752

5HT6R
5-hydroxytryptamine receptor 6

1

1

High-throughput

0.494

High

124687

BCKD
Branched-chain alpha-ketoacid dehydrogenase kinase

1

6

High-throughput

0.489

High

124786

PDK4
[Pyruvate dehydrogenase

1

3

High-throughput

0.489

High

124832

TSSK6
Testis-specific serine/threonine-protein kinase 6

1

9

High-throughput

0.489

High

124833

TSSK1
Testis-specific serine/threonine-protein kinase 1

1

12

High-throughput

0.489

High

124685

DC1I1
Cytoplasmic dynein 1 intermediate chain 1

1

12

High-throughput

0.479

High

124688

EPHB6
Ephrin type-B receptor 6

1

7

High-throughput

0.479

High

124689

BIRC5
Baculoviral IAP repeat-containing protein 5

1

1

Small-scale

0.479

High

124690

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

124692

PHLP1
PH domain leucine-rich repeat-containing protein phosphatase 1

1

7

High-throughput

0.479

High

124694

BRD4
Bromodomain-containing protein 4

1

5

High-throughput

0.479

High

124695

NPHP4
Nephrocystin-4

1

1

High-throughput

0.479

High

124696

PP6R2
Serine/threonine-protein phosphatase 6 regulatory subunit 2

1

2

High-throughput

0.479

High

124697

OFD1
Centriole and centriolar satellite protein OFD1

1

1

High-throughput

0.479

High

124698

DNJB5
DnaJ homolog subfamily B member 5

1

11

High-throughput

0.479

High

124699

CIAO1
Probable cytosolic iron-sulfur protein assembly protein CIAO1

1

12

High-throughput

0.479

High

124700

RECQ4
ATP-dependent DNA helicase Q4

1

3

High-throughput

0.479

High

124701

RMP
Unconventional prefoldin RPB5 interactor 1

1

2

High-throughput

0.479

High

124703

MFN2
Mitofusin-2

1

2

High-throughput

0.479

High

124704

EPM2A
Laforin

1

2

High-throughput

0.479

High

124713

P53
Cellular tumor antigen p53

1

4

High-throughput

0.479

High

124714

LCK
Tyrosine-protein kinase Lck

1

15

High-throughput

0.479

High

124716

ENOA
Alpha-enolase

1

2

High-throughput

0.479

High

124717

NPM
Nucleophosmin

1

1

High-throughput

0.479

High

124721

MCR
Mineralocorticoid receptor

1

20

Small-scale

0.479

High

124724

UCHL1
Ubiquitin carboxyl-terminal hydrolase isozyme L1

1

5

Small-scale

0.479

High

124732

CEBPB
CCAAT/enhancer-binding protein beta

1

7

High-throughput

0.479

High

124733

PTN1
Tyrosine-protein phosphatase non-receptor type 1

1

3

High-throughput

0.479

High

124737

TNR6
Tumor necrosis factor receptor superfamily member 6

1

7

High-throughput

0.479

High

124740

LTK
Leukocyte tyrosine kinase receptor

1

19

High-throughput

0.479

High

124742

RFA3
Replication protein A 14 kDa subunit

1

4

High-throughput

0.479

High

124744

VGFR3
Vascular endothelial growth factor receptor 3

1

5

High-throughput

0.479

High

124745

CCNF
Cyclin-F

1

3

High-throughput

0.479

High

124746

BCL6
B-cell lymphoma 6 protein

1

1

Small-scale

0.479

High

124757

LIMK1
LIM domain kinase 1

1

20

High-throughput

0.479

High

124758

LIMK2
LIM domain kinase 2

1

9

High-throughput

0.479

High

124760

TERA
Transitional endoplasmic reticulum ATPase

1

4

High-throughput

0.479

High

124762

MAX
Protein max

1

3

High-throughput

0.479

High

124763

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

2

High-throughput

0.479

High

124764

GBB2
Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-2

1

11

High-throughput

0.479

High

124766

TLE2
Transducin-like enhancer protein 2

1

14

High-throughput

0.479

High

124767

DUSP2
Dual specificity protein phosphatase 2

1

5

High-throughput

0.479

High

124771

FOXC1
Forkhead box protein C1

1

4

High-throughput

0.479

High

124772

ERCC8
DNA excision repair protein ERCC-8

1

12

High-throughput

0.479

High

124773

DC1I2
Cytoplasmic dynein 1 intermediate chain 2

1

10

High-throughput

0.479

High

124777

SIM2
Single-minded homolog 2

1

11

High-throughput

0.479

High

124781

NBR1
Next to BRCA1 gene 1 protein

1

1

High-throughput

0.479

High

124785

NTRK2
BDNF/NT-3 growth factors receptor

1

18

High-throughput

0.479

High

124790

GLE1
mRNA export factor GLE1

1

5

High-throughput

0.479

High

124791

Q53SM6
Uncharacterized protein EPAS1

1

11

High-throughput

0.479

High

124792

DCAF6
DDB1- and CUL4-associated factor 6

1

14

High-throughput

0.479

High

124802

TRI67
Tripartite motif-containing protein 67

1

11

High-throughput

0.479

High

124805

NEK8
Serine/threonine-protein kinase Nek8

1

13

High-throughput

0.479

High

124807

TAXB1
Tax1-binding protein 1

1

8

High-throughput

0.479

High

124808

FBX11
F-box only protein 11

1

1

Small-scale

0.479

High

124811

WDTC1
WD and tetratricopeptide repeats protein 1

1

19

High-throughput

0.479

High

124812

POC1B
POC1 centriolar protein homolog B

1

13

High-throughput

0.479

High

124813

DCA11
DDB1- and CUL4-associated factor 11

1

7

High-throughput

0.479

High

124814

DCAF4
DDB1- and CUL4-associated factor 4

1

1

High-throughput

0.479

High

124818

BAP1
Ubiquitin carboxyl-terminal hydrolase BAP1

1

5

High-throughput

0.479

High

124819

AKAP1
A-kinase anchor protein 1, mitochondrial

1

5

High-throughput

0.479

High

124820

SYMPK
Symplekin

1

2

High-throughput

0.479

High

124825

SNR40
U5 small nuclear ribonucleoprotein 40 kDa protein

1

11

High-throughput

0.479

High

124835

DUS16
Dual specificity protein phosphatase 16

1

5

High-throughput

0.479

High

124836

AMRA1
Activating molecule in BECN1-regulated autophagy protein 1

1

14

High-throughput

0.479

High

124839

PKHA4
Pleckstrin homology domain-containing family A member 4

1

6

High-throughput

0.479

High

124840

EGLN3
Prolyl hydroxylase EGLN3

1

4

High-throughput

0.479

High

124841

NMRL1
NmrA-like family domain-containing protein 1

1

1

High-throughput

0.479

High

124846

HIF1N
Hypoxia-inducible factor 1-alpha inhibitor

1

1

High-throughput

0.479

High

124848

MKS1
Tectonic-like complex member MKS1

1

2

High-throughput

0.479

High

124849

WSB2
WD repeat and SOCS box-containing protein 2

1

13

High-throughput

0.479

High

124850

ZRAN1
Ubiquitin thioesterase ZRANB1

1

8

High-throughput

0.479

High

124810

FBXL6
F-box/LRR-repeat protein 6

1

12

High-throughput

0.470

High

124834

CLC7A
C-type lectin domain family 7 member A

1

0

High-throughput

0.460

High

124705

TBX18
T-box transcription factor TBX18

1

0

High-throughput

0.458

High

124706

BCL10
B-cell lymphoma/leukemia 10

1

0

Small-scale

0.458

High

124748

RL5
Large ribosomal subunit protein uL18

1

0

High-throughput

0.458

High

124794

DCA12
DDB1- and CUL4-associated factor 12

1

0

High-throughput

0.458

High

124823

FBXW5
F-box/WD repeat-containing protein 5

1

0

High-throughput

0.458

High

117612

K9JA46
Epididymis luminal secretory protein 52

1

20

High-throughput

0.445

High

124710

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

3

High-throughput

0.445

High

124729

CFTR
Cystic fibrosis transmembrane conductance regulator

1

7

High-throughput

0.445

High

124759

S12A3
Solute carrier family 12 member 3

1

9

High-throughput

0.445

High

124796

A16L1
Autophagy-related protein 16-1

1

14

High-throughput

0.445

High

124801

NBEL2
Neurobeachin-like protein 2

1

13

High-throughput

0.445

High

124806

Q86SX1
Full-length cDNA 5-PRIME end of clone CS0DN005YI08 of Adult brain of Homo sapiens

1

20

High-throughput

0.445

High

124837

S6A17
Sodium-dependent neutral amino acid transporter SLC6A17

1

1

High-throughput

0.445

High

124853

S12A4
Solute carrier family 12 member 4

1

9

High-throughput

0.445

High

124857

WIPI2
WD repeat domain phosphoinositide-interacting protein 2

1

17

High-throughput

0.445

High

124712

NTRK1
High affinity nerve growth factor receptor

1

18

High-throughput

0.437

High

124730

INSRR
Insulin receptor-related protein

1

14

High-throughput

0.437

High

124734

FGFR4
Fibroblast growth factor receptor 4

1

14

High-throughput

0.437

High

124735

FGFR3
Fibroblast growth factor receptor 3

1

13

High-throughput

0.437

High

124739

EPHA8
Ephrin type-A receptor 8

1

10

High-throughput

0.437

High

124769

DDR1
Epithelial discoidin domain-containing receptor 1

1

17

High-throughput

0.437

High

124782

NFIX
Nuclear factor 1 X-type

1

1

High-throughput

0.437

High

124787

Q308M6
DNA polymerase

1

3

High-throughput

0.437

High

124789

Q53G83
Small ribosomal subunit protein uS3

1

2

High-throughput

0.437

High

124798

Q6ICH2
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.437

High

124803

DET1
DET1 homolog

1

2

High-throughput

0.437

High

124804

WDR53
WD repeat-containing protein 53

1

8

High-throughput

0.437

High

124847

F120C
Constitutive coactivator of PPAR-gamma-like protein 2

1

2

High-throughput

0.437

High

124859

STYL1
Serine/threonine/tyrosine-interacting-like protein 1

1

4

High-throughput

0.437

High

124749

CEBPA
CCAAT/enhancer-binding protein alpha

1

7

High-throughput

0.408

High

73349

B2CML4
single-stranded DNA cytosine deaminase

1

1

High-throughput

0.407

High

124854

S27A6
Long-chain fatty acid transport protein 6

1

4

High-throughput

0.407

High

124728

TDGF1
Protein Cripto

4

0

High-throughput

0.360

High

124827

CC120
Coiled-coil domain-containing protein 120

3

0

High-throughput

0.345

High

124709

REL2
Prorelaxin H2 [Cleaved into: Relaxin B chain; Relaxin A chain]

1

0

High-throughput

0.279

Low

124770

SYCN
Syncollin

1

0

High-throughput

0.279

Low

124829

RIPR3
RIPOR family member 3

1

0

High-throughput

0.279

Low

124809

HROB
Homologous recombination OB-fold protein

1

0

Small-scale

0.249

Low

124858

WIF1
Wnt inhibitory factor 1

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025