HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: TAB2 (Q9NYJ8)
TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 (Mitogen-activated protein kinase kinase kinase 7-interacting protein 2) (TAK1-binding protein 2) (TAB-2) (TGF-beta-activated kinase 1-binding protein 2)
Gene: TAB2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.41	0.60	0.501

Property	Details
Experiments	12150997
Identification Methods	pull down
Interaction Type	direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 693
+	Hs
		177391 HDAC3_HUMAN (9-434): 0: 574: 57.94		TAB2_HUMAN (1-693): 1.25e-111: 354: 100.00
+	Mm
		140261 HDAC1_MOUSE (1-482): 0: 672: 99.38		SMCA4_MOUSE (201-665): 3.01e-44: 173: 11.52
+	Mm
		936385 HDAC2_MOUSE (1-478): 0: 664: 85.71		SMCA4_MOUSE (201-665): 3.01e-44: 173: 11.52
+	Mm
		292413 HDAC3_MOUSE (9-434): 0: 574: 58.18		SMCA4_MOUSE (201-665): 3.01e-44: 173: 11.52
+	Dm
		631303 Q7KTS4_DROME (7-435): 0: 564: 56.52		BRM_DROME (165-665): 1e-43: 172: 12.74
+	Hs
		846768 HDAC1_HUMAN (1-482): 0: 668: 100.00		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		846833 HDAC2_HUMAN (1-478): 0: 666: 85.92		SMCA2_HUMAN (127-396): 1.06e-10: 67.5: 10.22
+	Hs
		257609 HDAC1_HUMAN (1-482): 0: 668: 100.00		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		257678 HDAC2_HUMAN (1-478): 0: 666: 85.92		ANR17_HUMAN (117-519): 7.6e-10: 64.7: 11.54
+	Hs
		203227 HDAC1_HUMAN (1-482): 0: 668: 100.00		SYNJ1_HUMAN (303-658): 3.22e-09: 62.5: 9.55
+	Hs
		846962 HDAC1_HUMAN (1-482): 0: 668: 100.00		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		847037 HDAC2_HUMAN (1-478): 0: 666: 85.92		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		177241 HDAC3_HUMAN (9-434): 0: 574: 57.94		SMCA4_HUMAN (111-415): 6.46e-09: 61.7: 8.81
+	Hs
		980012 HDAC6_HUMAN (16-325): 2.05e-93: 309: 25.78		IF4G1_HUMAN (71-521): 3.73e-21: 101: 8.28