HitPredict

Interactor 1: HDAC1 (Q13547)
Histone deacetylase 1 (HD1) (EC 3.5.1.98) (Protein deacetylase HDAC1) (EC 3.5.1.-) (Protein decrotonylase HDAC1) (EC 3.5.1.-)
Gene: HDAC1

Interactor 2: MO4L1 (Q9UBU8)
Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (MRG15) (Protein MSL3-1) (Transcription factor-like protein MRG15)
Gene: MORF4L1

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.71	0.60	0.656

Property	Details
Experiments	28514442, 17573780, 20332121
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0006325 - chromatin organization GO:0045893 - positive regulation of DNA-templated transcription GO:0070822 - Sin3-type complex
Homologous interactions	6

Homologous interactions

Color coding for hit scores

	1 482 Hs			1 362
+	Mm
		140247 HDAC1_MOUSE (1-482): 0: 672: 99.38		MO4L1_MOUSE (1-362): 6.73e-173: 487: 99.72
+	Hs
		1270495 HDAC2_HUMAN (1-478): 0: 666: 85.92		MO4L1_HUMAN (1-362): 3.85e-173: 487: 100.00
+	Hs
		1038389 HDAC1_HUMAN (1-482): 0: 668: 100.00		MO4L2_HUMAN (111-362): 3.81e-106: 314: 76.10
+	Hs
		1063022 HDAC2_HUMAN (1-478): 0: 666: 85.92		MO4L2_HUMAN (111-362): 3.81e-106: 314: 76.10
+	Dm
		1276561 HDAC1_DROME (6-477): 0: 658: 77.33		EAF3_DROME (2-361): 1.73e-104: 315: 34.89
+	Sc
		693077 RPD3_YEAST (8-421): 0: 580: 61.48		EAF3_YEAST (6-362): 6.17e-121: 356: 27.00