HitPredict

Interactor 1: LAPM5 (Q13571)
Lysosomal-associated transmembrane protein 5 (Lysosomal-associated multitransmembrane protein 5) (Retinoic acid-inducible E3 protein)
Gene: LAPTM5

Interactor 2: NED4L (Q96PU5)
E3 ubiquitin-protein ligase NEDD4-like (EC 2.3.2.26) (EC 2.3.2.36) (HECT-type E3 ubiquitin transferase NED4L) (NEDD4.2) (Nedd4-2)
Gene: NEDD4L

Species: Homo sapiens

Source: mint

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.65	0.60	0.625

Property	Details
Experiments	33961781, 15231748
Identification Methods	affinity chromatography technology, two hybrid, anti tag coimmunoprecipitation
Interaction Type	physical association, direct interaction, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 262 Hs			1 975
+	Hs
		1039515 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		WWP1_HUMAN (1-972): 0: 781: 33.13
+	Mm
		808355 LAPM5_MOUSE (1-262): 4.27e-144: 405: 79.01		NEDD4_MOUSE (12-975): 0: 794: 55.19
+	Hs
		1039511 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		ITCH_HUMAN (9-972): 0: 772: 33.16
+	Hs
		808116 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		NEDD4_HUMAN (94-975): 0: 724: 49.78
+	Hs
		808158 Q5TBB8_HUMAN (1-262): 2.03e-151: 424: 100.00		NEDD4_HUMAN (94-975): 0: 724: 49.78
+	Hs
		125438 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		WWP2_HUMAN (228-972): 0: 719: 37.80
+	Hs
		1039518 LAPM5_HUMAN (1-262): 2.03e-151: 424: 100.00		SMUF2_HUMAN (21-324): 2e-29: 127: 22.56