HitPredict

Interactor 1: NOG1 (Q02892)
Nucleolar GTP-binding protein 1
Gene: NOG1

Interactor 2: DBP10 (Q12389)
ATP-dependent RNA helicase DBP10 (EC 3.6.4.13) (DEAD box protein 10)
Gene: DBP10

Species: Saccharomyces cerevisiae S288C

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.87	0.60	0.723

Property	Details
Experiments	38113283, 38632236, 25877921, 37968396, 23874617, unassigned1262
Identification Methods	affinity chromatography technology, two hybrid, two hybrid array, validated two hybrid
Interaction Type	physical association, direct interaction

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0003723 - RNA binding GO:0005730 - nucleolus GO:0006364 - rRNA processing GO:0030687 - preribosome, large subunit precursor GO:1902626 - assembly of large subunit precursor of preribosome
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 647 Sc			1 995
+	Sc
		666535 NOG1_YEAST (1-647): 0: 628: 100.00		DBP2_YEAST (32-566): 6.2e-130: 406: 22.20
+	Dm
		1344108 NOG1_DROME (3-647): 0: 577: 47.13		Q8SY39_DROME (139-994): 1.16e-132: 422: 30.67
+	Dm
		1266511 NOG1_DROME (3-647): 0: 577: 47.13		Q7K4L8_DROME (4-579): 1.6e-111: 362: 21.61
+	Dm
		1261335 NOG1_DROME (3-647): 0: 577: 47.13		Q7JQN4_DROME (138-547): 2.63e-50: 192: 33.17
+	Dm
		654206 128UP_DROME (98-494): 6.63e-79: 257: 13.02		DDX6_DROME (111-559): 3.36e-143: 437: 25.17
+	Hs
		1351086 DRG1_HUMAN (98-494): 3.83e-81: 262: 14.22		DDX54_HUMAN (59-993): 3.21e-130: 417: 31.22
+	Sc
		666466 RBG1_YEAST (98-494): 2.45e-73: 242: 12.87		DBP2_YEAST (32-566): 6.2e-130: 406: 22.20
+	Dm
		654235 ARF1_DROME (165-341): 2.3e-52: 180: 12.43		DDX6_DROME (111-559): 3.36e-143: 437: 25.17
+	Hs
		141348 TRI23_HUMAN (71-341): 4.93e-53: 193: 13.90		DDX3X_HUMAN (5-565): 7.29e-134: 420: 20.76
+	Sc
		444580 RBG2_YEAST (103-494): 3.02e-63: 215: 14.50		DED1_YEAST (1-567): 1.74e-118: 377: 22.07