HitPredict

Interactor 1: TRA2A (Q13595)
Transformer-2 protein homolog alpha (TRA-2 alpha) (TRA2-alpha) (Transformer-2 protein homolog A)
Gene: TRA2A

Interactor 2: SRRM1 (Q8IYB3)
Serine/arginine repetitive matrix protein 1 (SR-related nuclear matrix protein of 160 kDa) (SRm160) (Ser/Arg-related nuclear matrix protein)
Gene: SRRM1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	0.60	0.667

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0000398 - mRNA splicing, via spliceosome GO:0003723 - RNA binding GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005681 - spliceosomal complex
Homologous interactions	8

Homologous interactions

Color coding for hit scores

	1 282 Hs			1 904
+	Hs
		1040445 TRA2A_HUMAN (1-253): 2.19e-47: 161: 100.00		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		1031402 PABP4_HUMAN (1-267): 6.75e-38: 142: 14.13		ATX2L_HUMAN (104-788): 2.79e-11: 69.6: 10.35
+	Hs
		516606 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		ATX2L_HUMAN (104-788): 2.79e-11: 69.6: 10.35
+	Hs
		516595 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		KMT2C_HUMAN (390-904): 1.47e-09: 64.6: 11.65
+	Hs
		516749 PABP1_HUMAN (1-267): 1.05e-37: 142: 13.77		SRRM2_HUMAN (189-896): 4.93e-09: 62.6: 13.28
+	Hs
		965152 PABP3_HUMAN (1-267): 3.29e-34: 132: 13.77		ANK2_HUMAN (110-849): 7.77e-11: 68.6: 14.10
+	Hs
		1259851 PPIL4_HUMAN (117-195): 7.73e-27: 110: 39.24		ATX2L_HUMAN (104-788): 2.79e-11: 69.6: 10.35
+	Ce
		107192 SIG7_CAEEL (117-277): 8.83e-23: 98.7: 25.47		RPB1_CAEEL (308-440): 1.25e-09: 64.4: 18.30