HitPredict

Interactor 1: SNX1 (Q13596)
Sorting nexin-1
Gene: SNX1

Interactor 2: DYN3 (Q9UQ16)
Dynamin-3 (EC 3.6.5.5) (Dynamin, testicular) (T-dynamin)
Gene: DNM3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.74	1.00	0.861

Property	Details
Experiments	26186194, 28514442, 33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	PH~PX
Common GO terms	GO:0005737 - cytoplasm GO:0031623 - receptor internalization
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 522 Hs			1 869
+	Hs
		240458 SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		240366 SNX2_HUMAN (10-522): 3.61e-127: 382: 58.95		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		1357820 SNX9_HUMAN (2-518): 1.33e-93: 298: 14.58		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		1261052 SNX33_HUMAN (3-521): 4.73e-90: 288: 15.33		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		840797 SNX18_HUMAN (7-477): 5.44e-96: 305: 18.15		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		840879 SNX9_HUMAN (2-518): 1.33e-93: 298: 14.58		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		2824 SNX9_HUMAN (2-518): 1.33e-93: 298: 14.58		A0A0D9SFE4_HUMAN (1-869): 0: 1038: 77.96
+	Hs
		983421 SNX9_HUMAN (2-518): 1.33e-93: 298: 14.58		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Hs
		840772 SNX33_HUMAN (3-521): 4.73e-90: 288: 15.33		DYN2_HUMAN (1-869): 0: 1041: 79.21
+	Hs
		1357821 SNX5_HUMAN (142-520): 9.13e-75: 243: 21.45		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Hs
		983396 SNX33_HUMAN (3-521): 4.73e-90: 288: 15.33		DYN1_HUMAN (1-852): 0: 1035: 78.56
+	Hs
		1357510 SNX6_HUMAN (145-520): 1.81e-73: 240: 20.46		DYN3_HUMAN (1-869): 0: 1080: 100.00
+	Ce
		760504 LST4_CAEEL (10-519): 2.56e-77: 255: 16.32		DYN1_CAEEL (3-815): 0: 947: 62.09
+	Sc
		599475 MVP1_YEAST (57-515): 8.99e-71: 236: 16.23		VPS1_YEAST (7-745): 0: 605: 34.31