Protein: STAG2
Cohesin subunit SA-2 (SCC3 homolog 2) (Stromal antigen 2)

Gene: STAG2
Organism: Homo sapiens
Interactions: 216
UniProt ID: Q8N3U4

Gene Ontology (top 5):
GO:0000775 - chromosome, centromeric region
GO:0000785 - chromatin
GO:0001650 - fibrillar center
GO:0003682 - chromatin binding
GO:0005634 - nucleus

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1325365

STAG1
Cohesin subunit SA-1

10

4

Small-scale

0.970

High

238562

RAD21
Double-strand-break repair protein rad21 homolog

20

14

Small-scale

0.766

High

1325410

SMC3
Structural maintenance of chromosomes protein 3

16

20

Small-scale

0.762

High

1130102

SMC1A
Structural maintenance of chromosomes protein 1A

11

20

Small-scale

0.757

High

1279199

WAPL
Wings apart-like protein homolog

9

2

Small-scale

0.754

High

1325374

CDCA5
Sororin

9

1

Small-scale

0.752

High

1177598

PDS5A
Sister chromatid cohesion protein PDS5 homolog A

7

15

Small-scale

0.742

High

1325398

PDS5B
Sister chromatid cohesion protein PDS5 homolog B

5

18

Small-scale

0.709

High

733505

GP183
G-protein coupled receptor 183

3

4

High-throughput

0.667

High

906112

AL3A2
Aldehyde dehydrogenase family 3 member A2

3

0

High-throughput

0.638

High

1204372

SGO1
Shugoshin 1

3

0

Small-scale

0.638

High

1291627

CMTD1
Catechol O-methyltransferase domain-containing protein 1

3

0

High-throughput

0.638

High

1325375

VSIG2
V-set and immunoglobulin domain-containing protein 2

3

0

High-throughput

0.638

High

1325361

SIGL1
SIGLEC family-like protein 1

2

1

High-throughput

0.628

High

1325359

STAG2
Cohesin subunit SA-2

1

4

High-throughput

0.618

High

996768

TBA1B
Tubulin alpha-1B chain

2

1

High-throughput

0.611

High

1235652

NIPBL
Nipped-B-like protein

2

4

High-throughput

0.611

High

1325360

PNKD
Probable thioesterase PNKD

2

1

High-throughput

0.611

High

1325381

PI51A
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha

2

1

High-throughput

0.611

High

1325400

OCAD1
OCIA domain-containing protein 1

2

1

High-throughput

0.601

High

980925

H2B1C
Histone H2B type 1-C/E/F/G/I

2

4

High-throughput

0.584

High

998539

H31
Histone H3.1

2

5

High-throughput

0.584

High

1325370

UBP13
Ubiquitin carboxyl-terminal hydrolase 13

2

1

Small-scale

0.584

High

438092

GLPB
Glycophorin-B

2

1

High-throughput

0.574

High

770889

OPRM
Mu-type opioid receptor

2

2

High-throughput

0.574

High

1029613

CD83
CD83 antigen

2

1

High-throughput

0.574

High

1325395

SSU72
RNA polymerase II subunit A C-terminal domain phosphatase SSU72

1

0

Small-scale

0.571

High

396498

ESR1
Estrogen receptor

2

2

High-throughput

0.571

High

620473

NUCL
Nucleolin

2

0

High-throughput

0.559

High

979979

H4
Histone H4

2

0

High-throughput

0.559

High

1138390

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

2

0

High-throughput

0.559

High

210409

MTLR
Motilin receptor

1

3

High-throughput

0.536

High

326154

REC8
Meiotic recombination protein REC8 homolog

1

1

High-throughput

0.536

High

388247

GLPA
Glycophorin-A

1

1

High-throughput

0.536

High

1010671

DCD
Dermcidin

1

1

High-throughput

0.536

High

1022909

EFNB1
Ephrin-B1

1

1

High-throughput

0.536

High

1325382

FOXB1
Forkhead box protein B1

1

2

High-throughput

0.536

High

1325383

CITE1
Cbp/p300-interacting transactivator 1

1

1

High-throughput

0.536

High

1325386

HDAC8
Histone deacetylase 8

1

2

High-throughput

0.536

High

1325390

F234A
Protein FAM234A

1

1

High-throughput

0.536

High

1325412

KLH20
Kelch-like protein 20

1

1

High-throughput

0.536

High

1286993

UBP37
Ubiquitin carboxyl-terminal hydrolase 37

1

1

Small-scale

0.515

High

391347

FRIL
Ferritin light chain

1

0

High-throughput

0.513

High

649744

SPR1B
Cornifin-B

1

0

High-throughput

0.513

High

881672

FNTA
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha

1

0

High-throughput

0.513

High

911304

IMA5
Importin subunit alpha-5

1

0

High-throughput

0.513

High

1100895

G3BP1
Ras GTPase-activating protein-binding protein 1

1

0

High-throughput

0.513

High

1325369

XPF
DNA repair endonuclease XPF

1

0

High-throughput

0.513

High

1325378

CDC5L
Cell division cycle 5-like protein

1

0

High-throughput

0.513

High

1325380

KI2L4
Killer cell immunoglobulin-like receptor 2DL4

1

0

High-throughput

0.513

High

1325407

CC018
Uncharacterized protein C3orf18

1

0

High-throughput

0.513

High

1325411

HIG1A
HIG1 domain family member 1A, mitochondrial

1

0

High-throughput

0.513

High

920112

PLK1
Serine/threonine-protein kinase PLK1

1

1

Small-scale

0.501

High

595512

H15
Histone H1.5

1

0

High-throughput

0.493

High

1325406

MD2L2
Mitotic spindle assembly checkpoint protein MAD2B

1

0

High-throughput

0.493

High

640220

EPHA1
Ephrin type-A receptor 1

1

1

High-throughput

0.489

High

640418

C5AR1
C5a anaphylatoxin chemotactic receptor 1

1

2

High-throughput

0.489

High

683283

TNR5
Tumor necrosis factor receptor superfamily member 5

1

1

High-throughput

0.489

High

914300

EFNA4
Ephrin-A4

1

1

High-throughput

0.489

High

1101584

GPR17
Uracil nucleotide/cysteinyl leukotriene receptor

1

4

High-throughput

0.489

High

1249812

BTNL9
Butyrophilin-like protein 9

1

1

High-throughput

0.489

High

1325388

SEM4C
Semaphorin-4C

1

2

High-throughput

0.489

High

1325419

NPTN
Neuroplastin

1

1

High-throughput

0.489

High

951758

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

0

High-throughput

0.480

High

964367

SUMO2
Small ubiquitin-related modifier 2

1

0

High-throughput

0.480

High

728334

AKT1
RAC-alpha serine/threonine-protein kinase

1

0

High-throughput

0.479

High

143117

NFIB
Nuclear factor 1 B-type

1

3

High-throughput

0.479

High

157607

CTRO
Citron Rho-interacting kinase

1

2

High-throughput

0.479

High

190993

RPA34
DNA-directed RNA polymerase I subunit RPA34

1

3

High-throughput

0.479

High

243677

SMCA5
SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A member 5

1

1

High-throughput

0.479

High

255836

USO1
General vesicular transport factor p115

1

3

High-throughput

0.479

High

256927

H2B1K
Histone H2B type 1-K

1

4

High-throughput

0.479

High

272319

OBSL1
Obscurin-like protein 1

1

1

High-throughput

0.479

High

272839

PHF2
Lysine-specific demethylase PHF2

1

1

High-throughput

0.479

High

285992

SF3B1
Splicing factor 3B subunit 1

1

2

High-throughput

0.479

High

289613

U520
U5 small nuclear ribonucleoprotein 200 kDa helicase

1

2

High-throughput

0.479

High

321588

PRP6
Pre-mRNA-processing factor 6

1

1

High-throughput

0.479

High

346065

STAU1
Double-stranded RNA-binding protein Staufen homolog 1

1

2

High-throughput

0.479

High

372563

MYC
Myc proto-oncogene protein

1

2

High-throughput

0.479

High

404222

GCR
Glucocorticoid receptor

1

2

High-throughput

0.479

High

474123

NFIC
Nuclear factor 1 C-type

1

3

High-throughput

0.479

High

487526

PARP1
Poly [ADP-ribose] polymerase 1

1

1

High-throughput

0.479

High

508272

UBC
Polyubiquitin-C [Cleaved into: Ubiquitin]

1

1

High-throughput

0.479

High

537509

HSP7C
Heat shock cognate 71 kDa protein

1

1

High-throughput

0.479

High

637626

FLNA
Filamin-A

1

1

High-throughput

0.479

High

695935

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.479

High

729351

HNRH1
Heterogeneous nuclear ribonucleoprotein H

1

1

High-throughput

0.479

High

754912

H2B1B
Histone H2B type 1-B

1

4

High-throughput

0.479

High

771007

RORA
Nuclear receptor ROR-alpha

1

1

High-throughput

0.479

High

791527

SYUA
Alpha-synuclein

1

1

High-throughput

0.479

High

854160

KI67
Proliferation marker protein Ki-67

1

2

High-throughput

0.479

High

883609

CENPA
Histone H3-like centromeric protein A

1

5

High-throughput

0.479

High

887021

CEBPA
CCAAT/enhancer-binding protein alpha

1

1

High-throughput

0.479

High

934854

TERA
Transitional endoplasmic reticulum ATPase

1

1

High-throughput

0.479

High

937294

DSRAD
Double-stranded RNA-specific adenosine deaminase

1

2

High-throughput

0.479

High

960655

HAND2
Heart- and neural crest derivatives-expressed protein 2

1

1

High-throughput

0.479

High

996242

EF1A1
Elongation factor 1-alpha 1

1

1

High-throughput

0.479

High

1008234

PRKDC
DNA-dependent protein kinase catalytic subunit

1

2

High-throughput

0.479

High

1017019

H33
Histone H3.3

1

5

High-throughput

0.479

High

1027586

HNRPU
Heterogeneous nuclear ribonucleoprotein U

1

1

High-throughput

0.479

High

1035770

KIF23
Kinesin-like protein KIF23

1

3

High-throughput

0.479

High

1087867

NFIA
Nuclear factor 1 A-type

1

3

High-throughput

0.479

High

1098057

PSMD2
26S proteasome non-ATPase regulatory subunit 2

1

1

High-throughput

0.479

High

1113680

CUL3
Cullin-3

1

1

High-throughput

0.479

High

1119847

CKAP5
Cytoskeleton-associated protein 5

1

1

High-throughput

0.479

High

1130783

RRP5
Protein RRP5 homolog

1

1

High-throughput

0.479

High

1133532

NFIX
Nuclear factor 1 X-type

1

3

High-throughput

0.479

High

1145821

IRF4
Interferon regulatory factor 4

1

1

Small-scale

0.479

High

1147955

SF3B3
Splicing factor 3B subunit 3

1

2

High-throughput

0.479

High

1157809

DDB1
DNA damage-binding protein 1

1

2

High-throughput

0.479

High

1217155

RIF1
Telomere-associated protein RIF1

1

2

High-throughput

0.479

High

1247950

ANR11
Ankyrin repeat domain-containing protein 11

1

1

High-throughput

0.479

High

1310087

MGAP
MAX gene-associated protein

1

1

High-throughput

0.479

High

1313256

SMC5
Structural maintenance of chromosomes protein 5

1

15

High-throughput

0.479

High

1314653

SRRM1
Serine/arginine repetitive matrix protein 1

1

2

High-throughput

0.479

High

1325362

AFG2A
ATPase family gene 2 protein homolog A

1

1

High-throughput

0.479

High

1325366

PRP31
U4/U6 small nuclear ribonucleoprotein Prp31

1

1

High-throughput

0.479

High

1325367

GCN1
Stalled ribosome sensor GCN1

1

3

High-throughput

0.479

High

1325368

ESR2
Estrogen receptor beta

1

2

High-throughput

0.479

High

1325373

SPDLY
Protein Spindly

1

1

High-throughput

0.479

High

1325379

PSMD1
26S proteasome non-ATPase regulatory subunit 1

1

1

High-throughput

0.479

High

1325384

TBA1C
Tubulin alpha-1C chain

1

1

High-throughput

0.479

High

1325385

FACD2
Fanconi anemia group D2 protein

1

1

High-throughput

0.479

High

1325389

DDX47
Probable ATP-dependent RNA helicase DDX47

1

2

High-throughput

0.479

High

1325396

DDX21
Nucleolar RNA helicase 2

1

1

High-throughput

0.479

High

1325399

MDN1
Midasin

1

1

High-throughput

0.479

High

1325401

BCLF1
Bcl-2-associated transcription factor 1

1

4

High-throughput

0.479

High

1325405

ZRAN1
Ubiquitin thioesterase ZRANB1

1

3

High-throughput

0.479

High

1325413

TR150
Thyroid hormone receptor-associated protein 3

1

5

High-throughput

0.479

High

1325416

TRRAP
Transformation/transcription domain-associated protein

1

2

High-throughput

0.479

High

1325418

TF3C3
General transcription factor 3C polypeptide 3

1

1

High-throughput

0.479

High

173063

XPO1
Exportin-1

1

0

High-throughput

0.458

High

229043

AKAP8
A-kinase anchor protein 8

1

0

High-throughput

0.458

High

242268

PRKN
E3 ubiquitin-protein ligase parkin

1

0

High-throughput

0.458

High

260177

BRD4
Bromodomain-containing protein 4

1

0

High-throughput

0.458

High

271724

HIP1R
Huntingtin-interacting protein 1-related protein

1

0

High-throughput

0.458

High

445964

ENOA
Alpha-enolase

1

0

High-throughput

0.458

High

551153

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

589149

RFA2
Replication protein A 32 kDa subunit

1

0

High-throughput

0.458

High

608665

DDX5
Probable ATP-dependent RNA helicase DDX5

1

0

High-throughput

0.458

High

697176

APEX1
DNA repair nuclease/redox regulator APEX1

1

0

High-throughput

0.458

High

731462

STIP1
Stress-induced-phosphoprotein 1

1

0

High-throughput

0.458

High

768637

RFA3
Replication protein A 14 kDa subunit

1

0

High-throughput

0.458

High

799980

COIL
Coilin

1

0

High-throughput

0.458

High

831058

CCNF
Cyclin-F

1

0

High-throughput

0.458

High

846381

MATR3
Matrin-3

1

0

High-throughput

0.458

High

862900

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

0

High-throughput

0.458

High

868734

LEG7
Galectin-7

1

0

High-throughput

0.458

High

872527

SOX2
Transcription factor SOX-2

1

0

Small-scale

0.458

High

881238

FAS
Fatty acid synthase

1

0

High-throughput

0.458

High

890665

RGS3
Regulator of G-protein signaling 3

1

0

High-throughput

0.458

High

896822

DYN2
Dynamin-2

1

0

High-throughput

0.458

High

939385

EIF3B
Eukaryotic translation initiation factor 3 subunit B

1

0

High-throughput

0.458

High

952956

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.458

High

985762

RL11
Large ribosomal subunit protein uL5

1

0

High-throughput

0.458

High

999380

HBB
Hemoglobin subunit beta

1

0

High-throughput

0.458

High

1005913

GTF2I
General transcription factor II-I

1

0

High-throughput

0.458

High

1023112

RBM10
RNA-binding protein 10

1

0

High-throughput

0.458

High

1040850

MECOM
Histone-lysine N-methyltransferase MECOM

1

0

High-throughput

0.458

High

1085778

TF3C1
General transcription factor 3C polypeptide 1

1

0

High-throughput

0.458

High

1097417

CBX3
Chromobox protein homolog 3

1

0

High-throughput

0.458

High

1107017

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.458

High

1124494

MAP7
Ensconsin

1

0

High-throughput

0.458

High

1126473

CAPR1
Caprin-1

1

0

High-throughput

0.458

High

1127002

RBM39
RNA-binding protein 39

1

0

High-throughput

0.458

High

1129341

TRIPC
E3 ubiquitin-protein ligase TRIP12

1

0

High-throughput

0.458

High

1144709

PWP2
Periodic tryptophan protein 2 homolog

1

0

High-throughput

0.458

High

1152372

ZN174
Zinc finger protein 174

1

0

High-throughput

0.458

High

1229173

INT3
Integrator complex subunit 3

1

0

High-throughput

0.458

High

1229563

VIR
Protein virilizer homolog

1

0

High-throughput

0.458

High

1311938

SKA3
Spindle and kinetochore-associated protein 3

1

0

Small-scale

0.458

High

1325363

ANKK1
Ankyrin repeat and protein kinase domain-containing protein 1

1

0

High-throughput

0.458

High

1325371

E2F7
Transcription factor E2F7

1

0

High-throughput

0.458

High

1325372

DCPS
m7GpppX diphosphatase

1

0

High-throughput

0.458

High

1325376

ZN363
RING finger and CHY zinc finger domain-containing protein 1

1

0

High-throughput

0.458

High

1325377

RBM15
RNA-binding protein 15

1

0

High-throughput

0.458

High

1325387

OSBL8
Oxysterol-binding protein-related protein 8

1

0

High-throughput

0.458

High

1325392

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

1325397

SIR7
NAD-dependent protein deacetylase sirtuin-7

1

0

High-throughput

0.458

High

1325409

PRR12
Proline-rich protein 12

1

0

High-throughput

0.458

High

1325415

ZN330
Zinc finger protein 330

1

0

High-throughput

0.458

High

1325417

MARF1
Meiosis regulator and mRNA stability factor 1

1

0

High-throughput

0.458

High

1325420

SCC4
MAU2 chromatid cohesion factor homolog

1

0

High-throughput

0.458

High

72295

A9IYQ1
PDS5 cohesin associated factor B

1

13

High-throughput

0.445

High

132747

BMAL1
Basic helix-loop-helix ARNT-like protein 1

1

1

Small-scale

0.445

High

171511

S27A2
Long-chain fatty acid transport protein 2

1

2

High-throughput

0.445

High

192940

CLOCK
Circadian locomoter output cycles protein kaput

1

1

Small-scale

0.445

High

890359

NU153
Nuclear pore complex protein Nup153

1

3

Small-scale

0.445

High

1017448

FOXK1
Forkhead box protein K1

1

2

Small-scale

0.445

High

1240900

S27A4
Long-chain fatty acid transport protein 4

1

2

High-throughput

0.445

High

1325404

ZMYM2
Zinc finger MYM-type protein 2

1

1

Small-scale

0.445

High

1325414

ZN281
Zinc finger protein 281

1

1

Small-scale

0.445

High

503693

CC175
Coiled-coil domain-containing protein 175

1

4

High-throughput

0.437

High

1081689

K2012
Uncharacterized protein KIAA2012

1

4

High-throughput

0.437

High

1160685

DREB
Drebrin

1

3

High-throughput

0.437

High

1254623

TRI67
Tripartite motif-containing protein 67

1

1

High-throughput

0.437

High

1325364

WFDC5
WAP four-disulfide core domain protein 5

1

1

Small-scale

0.437

High

1325393

PKHA4
Pleckstrin homology domain-containing family A member 4

1

1

High-throughput

0.437

High

862292

YAP1
Transcriptional coactivator YAP1

1

0

Small-scale

0.426

High

1094931

TRAF3
TNF receptor-associated factor 3

1

0

High-throughput

0.426

High

58868

PIPSL
Putative PIP5K1A and PSMD4-like protein

1

1

High-throughput

0.407

High

749232

CD70
CD70 antigen

2

0

High-throughput

0.328

High

1325408

ITBP2
Integrin beta-1-binding protein 2

1

0

High-throughput

0.282

High

1180912

DRB5
HLA class II histocompatibility antigen, DR beta 5 chain

1

0

High-throughput

0.279

Low

1228680

C102B
Coiled-coil domain-containing protein 102B

1

0

High-throughput

0.279

Low

1325391

UN93B
Protein unc-93 homolog B1

1

0

High-throughput

0.279

Low

506529

EBLN1
Endogenous Bornavirus-like nucleoprotein 1

1

0

High-throughput

0.269

Low

412254

NTRK1
High affinity nerve growth factor receptor

1

0

High-throughput

0.249

Low

963201

LYSC
Lysozyme C

1

0

High-throughput

0.249

Low

1011313

RT25
Small ribosomal subunit protein mS25

1

0

High-throughput

0.249

Low

1249015

LMBRL
Protein LMBR1L

1

0

High-throughput

0.249

Low

1325394

RXFP1
Relaxin receptor 1

1

0

High-throughput

0.249

Low

1325402

PSD3
PH and SEC7 domain-containing protein 3

1

0

High-throughput

0.249

Low

1325403

CALL5
Calmodulin-like protein 5

1

0

High-throughput

0.249

Low

166347

ZNT4
Probable proton-coupled zinc antiporter SLC30A4

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025