HitPredict

Interactor 1: MTMR3 (Q13615)
Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10)
Gene: MTMR3

Interactor 2: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 1198 Hs			1 768
+	Hs
		1042682 MTMR4_HUMAN (1-1198): 0: 1052: 47.79		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1041482 MTMR4_HUMAN (1-1198): 0: 1052: 47.79		CUL2_HUMAN (30-768): 0: 672: 26.17
+	Hs
		1042332 MTMR9_HUMAN (43-626): 0: 623: 26.89		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1043565 MTMRC_HUMAN (6-762): 7.29e-160: 496: 16.63		CUL4B_HUMAN (5-768): 0: 779: 36.77
+	Hs
		313535 ZFYV9_HUMAN (595-1197): 9.5e-67: 249: 15.35		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042352 RUFY1_HUMAN (987-1184): 3.72e-58: 216: 27.44		CUL3_HUMAN (1-768): 0: 951: 100.00
+	Hs
		1042155 RUFY2_HUMAN (987-1184): 3.6e-40: 160: 24.40		CUL3_HUMAN (1-768): 0: 951: 100.00