HitPredict

Interactor 1: MTMR3 (Q13615)
Myotubularin-related protein 3 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 1) (FYVE-DSP1) (Phosphatidylinositol-3,5-bisphosphate 3-phosphatase) (EC 3.1.3.95) (Phosphatidylinositol-3-phosphate phosphatase) (EC 3.1.3.64) (Zinc finger FYVE domain-containing protein 10)
Gene: MTMR3

Interactor 2: MTMR4 (Q9NYA4)
Myotubularin-related protein 4 (EC 3.1.3.48) (FYVE domain-containing dual specificity protein phosphatase 2) (FYVE-DSP2) (Zinc finger FYVE domain-containing protein 11)
Gene: MTMR4

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.84 1.00 0.919

The method score is based on:

Property Details
Experiments 26787466, 27880917, 25659891, 27432908, 28675297
Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains FYVE~FYVE, Myotub-related~Myotub-related
Common GO terms GO:0004438 - phosphatidylinositol-3-phosphate phosphatase activity
GO:0004722 - protein serine/threonine phosphatase activity
GO:0004725 - protein tyrosine phosphatase activity
GO:0005737 - cytoplasm
GO:0005829 - cytosol
and 9 others

more...
Homologous interactions 18

Homologous interactions

Color coding for hit scores

1 1198
Hs

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Last updated: 15 Jul 2024