Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1
Interactor 2: FBXW7 (Q969H0)
F-box/WD repeat-containing protein 7 (Archipelago homolog) (hAgo) (F-box and WD-40 domain-containing protein 7) (F-box protein FBX30) (SEL-10) (hCdc4)
Gene: FBXW7
Species: Homo sapiens
Source: mint
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.98 | 1.00 | 0.992 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 25143387, 22524983, 25515538, 25720964, 26976582, 28514442, 28007894, 28522751, 29408378, 29695787, 11585921, 32086376, 31285543, 32350066, 33961781, 22405651, 22388891, 21205095, 11565034, 23322298 and 8 others
more... |
| Identification Methods | affinity chromatography technology, pull down, biochemical, fluorescent resonance energy transfer, tandem affinity purification, anti tag coimmunoprecipitation, coimmunoprecipitation |
| Interaction Type | physical association, direct interaction, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cullin~F-box-like |
| Common GO terms | GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016567 - protein ubiquitination and 6 others more... |
| Homologous interactions | 20 |
Homologous interactions (Top 20)
Color coding for hit scores 
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Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
