HitPredict

Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: SPDLY (Q96EA4)
Protein Spindly (hSpindly) (Arsenite-related gene 1 protein) (Coiled-coil domain-containing protein 99) (Rhabdomyosarcoma antigen MU-RMS-40.4A) (Spindle apparatus coiled-coil domain-containing protein 1)
Gene: SPDL1

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30258100
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	18

Homologous interactions

Color coding for hit scores

	1 776 Hs			1 605
+	Hs
		1042944 CUL3_HUMAN (9-776): 0: 748: 30.47		MRCKB_HUMAN (5-542): 2e-75: 264: 18.02
+	Hs
		724815 CUL1_HUMAN (1-776): 0: 911: 100.00		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		725156 CUL1_HUMAN (1-776): 0: 911: 100.00		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		551697 CUL3_HUMAN (9-776): 0: 748: 30.47		DESP_HUMAN (15-507): 8.07e-47: 179: 14.37
+	Hs
		254479 CUL3_HUMAN (9-776): 0: 748: 30.47		ROCK2_HUMAN (2-601): 2.07e-45: 175: 18.70
+	Hs
		877410 CUL3_HUMAN (9-776): 0: 748: 30.47		LAMB2_HUMAN (95-434): 1.66e-44: 173: 14.57
+	Hs
		551696 CUL2_HUMAN (13-776): 0: 720: 35.98		DESP_HUMAN (15-507): 8.07e-47: 179: 14.37
+	Hs
		725158 CUL4A_HUMAN (7-776): 0: 781: 30.41		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		1035170 CUL4A_HUMAN (7-776): 0: 781: 30.41		ROCK1_HUMAN (18-586): 5.64e-11: 67.9: 10.33
+	Hs
		502830 CUL4A_HUMAN (7-776): 0: 781: 30.41		LAMC1_HUMAN (12-347): 5.01e-10: 64.8: 12.33
+	Hs
		1043487 CUL4B_HUMAN (7-776): 0: 773: 29.90		MY18A_HUMAN (36-569): 9.74e-11: 67.1: 14.03
+	Hs
		724816 CUL3_HUMAN (9-776): 0: 748: 30.47		MYH9_HUMAN (4-596): 3.84e-17: 87.9: 13.74
+	Hs
		725157 CUL3_HUMAN (9-776): 0: 748: 30.47		MYH10_HUMAN (4-596): 7.47e-17: 87.1: 11.71
+	Hs
		1041528 CUL3_HUMAN (9-776): 0: 748: 30.47		LAMB3_HUMAN (93-435): 1.19e-13: 76.5: 16.81
+	Hs
		433145 CUL3_HUMAN (9-776): 0: 748: 30.47		LAMB1_HUMAN (4-230): 1.14e-12: 73.6: 11.98
+	Hs
		1035169 CUL3_HUMAN (9-776): 0: 748: 30.47		ROCK1_HUMAN (18-586): 5.64e-11: 67.9: 10.33
+	Hs
		1042182 CUL3_HUMAN (9-776): 0: 748: 30.47		MY18A_HUMAN (36-569): 9.74e-11: 67.1: 14.03
+	Hs
		502829 CUL3_HUMAN (9-776): 0: 748: 30.47		LAMC1_HUMAN (12-347): 5.01e-10: 64.8: 12.33