Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1
Interactor 2: FBXL5 (Q9UKA1)
F-box/LRR-repeat protein 5 (F-box and leucine-rich repeat protein 5) (F-box protein FBL4/FBL5) (p45SKP2-like protein)
Gene: FBXL5
Species: Homo sapiens
Source: intact
Category: Small-scale
Confidence: High
| Method score | Annotation score | Interaction score |
|---|---|---|
| 0.95 | 0.90 | 0.927 |
The method score is based on:
| Property | Details |
|---|---|
| Experiments | 37028429, 19762596, 25249620, 27383304, 28514442, 32126207, 33961781, 37039990, 19762597, 22268729, 24157836, 24778179 |
| Identification Methods | affinity chromatography technology, biochemical, anti tag coimmunoprecipitation |
| Interaction Type | physical association, association |
The annotation score is based on:
| Property | Details |
|---|---|
| Interacting Pfam domains | Cullin~F-box-like |
| Common GO terms | GO:0005634 - nucleus GO:0005829 - cytosol GO:0016567 - protein ubiquitination GO:0019005 - SCF ubiquitin ligase complex GO:0031146 - SCF-dependent proteasomal ubiquitin-dependent protein catabolic process |
| Homologous interactions | 0 |
Service provided by Combinatics, Japan
Last updated: 15 Jul 2024
