Interactor 1: CUL1 (Q13616)
Cullin-1 (CUL-1)
Gene: CUL1

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score Annotation score Interaction score
0.98 1.00 0.995

The method score is based on:

Property Details
Experiments 10713156, 27910872, 29103612, 29499133, 29863914, 12609982, 31406304, 37028429, 15966899, 11850407, 18056411, 21249194, 9990852, 10023660, 21145461, 25143387, 25249620, 25332235, 25900982, 25515538 and 21 others

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Identification Methods affinity chromatography technology, proximity labelling technology, anti tag coimmunoprecipitation, tandem affinity purification, coimmunoprecipitation, anti bait coimmunoprecipitation
Interaction Type physical association, association

The annotation score is based on:

Property Details
Interacting Pfam domains Cullin~F-box-like
Common GO terms GO:0005654 - nucleoplasm
GO:0005737 - cytoplasm
GO:0005829 - cytosol
GO:0016567 - protein ubiquitination
GO:0019005 - SCF ubiquitin ligase complex
and 3 others

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Homologous interactions 20

Homologous interactions (Top 20)

Color coding for hit scores

1 776
Hs

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Last updated: 15 Jul 2024