HitPredict

Interactor 1: CUL2 (Q13617)
Cullin-2 (CUL-2)
Gene: CUL2

Interactor 2: ZY11B (Q9C0D3)
Protein zyg-11 homolog B
Gene: ZYG11B

Species: Homo sapiens

Source: mint

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.75	0.60	0.671

Property	Details
Experiments	17304241, 33961781, 21145461
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0031462 - Cul2-RING ubiquitin ligase complex
Homologous interactions	7

Homologous interactions

Color coding for hit scores

	1 745 Hs			1 744
+	Hs
		1041376 CUL2_HUMAN (1-745): 0: 840: 100.00		ZER1_HUMAN (10-729): 0: 669: 27.16
+	Hs
		1043082 CUL4A_HUMAN (4-745): 0: 773: 26.86		ZER1_HUMAN (10-729): 0: 669: 27.16
+	Ce
		1088872 CUL2_CAEEL (2-745): 0: 720: 42.27		ZER1_CAEEL (182-733): 9.86e-173: 520: 29.22
+	Ce
		1088863 CUL1_CAEEL (4-745): 0: 712: 30.76		ZER1_CAEEL (182-733): 9.86e-173: 520: 29.22
+	Ce
		599283 CUL2_CAEEL (2-745): 0: 720: 42.27		ZYG11_CAEEL (69-727): 9.64e-167: 501: 28.28
+	Ce
		1088876 CUL2_CAEEL (2-745): 0: 720: 42.27		Q9XTS0_CAEEL (83-674): 2.12e-158: 477: 16.05
+	Ce
		109334 CUL2_CAEEL (2-745): 0: 720: 42.27		H2KMM0_CAEEL (158-675): 9.03e-133: 417: 18.08