HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: PCH2 (Q15645)
Pachytene checkpoint protein 2 homolog (Human papillomavirus type 16 E1 protein-binding protein) (16E1-BP) (HPV16 E1 protein-binding protein) (Thyroid hormone receptor interactor 13) (Thyroid receptor-interacting protein 13) (TR-interacting protein 13) (TRIP-13)
Gene: TRIP13

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus
Homologous interactions	17

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 432
+	Hs
		913260 CUL3_HUMAN (1-768): 0: 951: 100.00		PRS10_HUMAN (2-426): 1.92e-94: 291: 17.67
+	Hs
		907019 CUL3_HUMAN (1-768): 0: 951: 100.00		PRS8_HUMAN (12-430): 9.46e-93: 287: 15.84
+	Hs
		798654 CUL3_HUMAN (1-768): 0: 951: 100.00		PRS6B_HUMAN (3-429): 4.23e-91: 283: 16.40
+	Hs
		1042836 CUL3_HUMAN (1-768): 0: 951: 100.00		VPS4A_HUMAN (105-389): 1.75e-75: 243: 23.78
+	Hs
		874907 CUL3_HUMAN (1-768): 0: 951: 100.00		TERA_HUMAN (126-424): 1.34e-66: 229: 19.06
+	Hs
		1042056 CUL3_HUMAN (1-768): 0: 951: 100.00		AFG2A_HUMAN (130-424): 2.06e-55: 198: 21.67
+	Hs
		913261 CUL4A_HUMAN (10-768): 0: 791: 38.32		PRS10_HUMAN (2-426): 1.92e-94: 291: 17.67
+	Hs
		260139 CUL3_HUMAN (1-768): 0: 951: 100.00		VPS4B_HUMAN (173-332): 7.58e-13: 72: 32.93
+	Hs
		874908 CUL4A_HUMAN (10-768): 0: 791: 38.32		TERA_HUMAN (126-424): 1.34e-66: 229: 19.06
+	Hs
		874909 CUL4B_HUMAN (5-768): 0: 779: 36.77		TERA_HUMAN (126-424): 1.34e-66: 229: 19.06
+	Hs
		874905 CUL1_HUMAN (18-768): 0: 707: 30.57		TERA_HUMAN (126-424): 1.34e-66: 229: 19.06
+	Sp
		784713 CUL3_SCHPO (11-768): 0: 648: 37.04		PRS8_SCHPO (27-420): 3.6e-92: 285: 18.05
+	Hs
		874906 CUL2_HUMAN (30-768): 0: 672: 26.17		TERA_HUMAN (126-424): 1.34e-66: 229: 19.06
+	Dm
		1097193 CUL1_DROME (29-768): 0: 669: 27.49		TERA_DROME (134-424): 1.81e-65: 225: 18.91
+	Sc
		968094 CDC53_YEAST (30-768): 0: 573: 22.08		PRS8_YEAST (27-423): 3.18e-94: 291: 17.33
+	Hs
		875192 CUL5_HUMAN (25-768): 0: 597: 23.77		TERA_HUMAN (126-424): 1.34e-66: 229: 19.06
+	Sc
		636771 CDC53_YEAST (30-768): 0: 573: 22.08		CDC48_YEAST (51-424): 4.75e-72: 243: 19.75