Protein: AT1B3
Sodium/potassium-transporting ATPase subunit beta-3 (Sodium/potassium-dependent ATPase subunit beta-3) (ATPB-3) (CD antigen CD298)

Gene: AT1B3, ATP1B3
Organism: Homo sapiens
Interactions: 220
UniProt ID: P54709

Gene Ontology (top 5):
GO:0001671 - ATPase activator activity
GO:0005886 - plasma membrane
GO:0005890 - sodium:potassium-exchanging ATPase complex
GO:0006883 - intracellular sodium ion homeostasis
GO:0016323 - basolateral plasma membrane

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

931220

AT12A
Potassium-transporting ATPase alpha chain 2

3

16

High-throughput

0.861

High

565586

AT1A3
Sodium/potassium-transporting ATPase subunit alpha-3

2

16

High-throughput

0.776

High

420449

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

16

High-throughput

0.691

High

698520

CALX
Calnexin

4

2

High-throughput

0.691

High

249037

NRP2
Neuropilin-2

3

2

High-throughput

0.667

High

520794

HLAC
HLA class I histocompatibility antigen, C alpha chain

3

2

High-throughput

0.667

High

931346

TGBR3
Transforming growth factor beta receptor type 3

3

1

High-throughput

0.667

High

931356

ITA7
Integrin alpha-7 [Cleaved into: Integrin alpha-7 heavy chain; Integrin alpha-7 light chain; Integrin alpha-7 70 kDa form]

3

1

High-throughput

0.667

High

931376

TBB8
Tubulin beta-8 chain

3

2

High-throughput

0.667

High

931420

BT2A2
Butyrophilin subfamily 2 member A2

3

1

High-throughput

0.667

High

931459

RTN4
Reticulon-4

3

4

High-throughput

0.667

High

297179

PRAF3
PRA1 family protein 3

3

0

High-throughput

0.638

High

931341

EFNB1
Ephrin-B1

3

0

High-throughput

0.638

High

931471

BACE2
Beta-secretase 2

3

0

High-throughput

0.638

High

931404

EMC1
ER membrane protein complex subunit 1

4

1

High-throughput

0.630

High

61095

T131L
Transmembrane protein 131-like

2

1

High-throughput

0.611

High

931437

TM9S2
Transmembrane 9 superfamily member 2

2

4

High-throughput

0.611

High

540377

LAMP1
Lysosome-associated membrane glycoprotein 1

3

0

High-throughput

0.606

High

690207

STOM
Stomatin

2

3

High-throughput

0.606

High

399674

HMDH
3-hydroxy-3-methylglutaryl-coenzyme A reductase

3

3

High-throughput

0.593

High

612049

ITB5
Integrin beta-5

2

0

High-throughput

0.585

High

931350

SMAGP
Small cell adhesion glycoprotein

2

0

High-throughput

0.580

High

931469

TMM98
Transmembrane protein 98

2

0

High-throughput

0.580

High

644485

PUR2
Trifunctional purine biosynthetic protein adenosine-3 [Includes: Phosphoribosylamine--glycine ligase

2

0

High-throughput

0.559

High

931439

ACE2
Angiotensin-converting enzyme 2

2

0

Small-scale

0.559

High

275503

RTN2
Reticulon-2

2

4

High-throughput

0.558

High

931397

GLBL2
Beta-galactosidase-1-like protein 2

2

1

High-throughput

0.558

High

717269

PEBP1
Phosphatidylethanolamine-binding protein 1

2

0

High-throughput

0.547

High

534828

BIP
Endoplasmic reticulum chaperone BiP

1

2

High-throughput

0.536

High

931326

PAR2
Proteinase-activated receptor 2

1

3

High-throughput

0.536

High

931344

LAT1
Large neutral amino acids transporter small subunit 1

1

3

High-throughput

0.536

High

931365

P2RY6
P2Y purinoceptor 6

1

4

High-throughput

0.536

High

931373

SGCB
Beta-sarcoglycan

1

4

High-throughput

0.536

High

931423

NDRG1
Protein NDRG1

1

4

High-throughput

0.536

High

931424

IGSF8
Immunoglobulin superfamily member 8

1

2

High-throughput

0.536

High

931466

NDRG3
Protein NDRG3

1

4

High-throughput

0.536

High

931378

MBRL
Membralin

2

1

Small-scale

0.533

High

931339

CNTP1
Contactin-associated protein 1

1

6

Small-scale

0.523

High

188846

TMPS2
Transmembrane protease serine 2

1

3

High-throughput

0.515

High

931393

TM11B
Transmembrane protease serine 11B

1

3

High-throughput

0.515

High

931461

TMPS4
Transmembrane protease serine 4

1

3

High-throughput

0.515

High

931468

CLC4E
C-type lectin domain family 4 member E

1

1

High-throughput

0.515

High

705287

GRN
Progranulin

1

0

High-throughput

0.513

High

931334

RB11A
Ras-related protein Rab-11A

1

0

High-throughput

0.513

High

931347

KPCZ
Protein kinase C zeta type

1

0

High-throughput

0.513

High

931370

VAMP3
Vesicle-associated membrane protein 3

1

0

High-throughput

0.513

High

931413

TIP
T-cell immunomodulatory protein

1

0

High-throughput

0.513

High

185556

OGT1
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit

1

2

High-throughput

0.501

High

410731

ERBB2
Receptor tyrosine-protein kinase erbB-2

1

3

High-throughput

0.500

High

931348

TYRO3
Tyrosine-protein kinase receptor TYRO3

1

2

High-throughput

0.500

High

931372

NTRK3
NT-3 growth factor receptor

1

3

High-throughput

0.500

High

277334

TP4A3
Protein tyrosine phosphatase type IVA 3

1

0

High-throughput

0.493

High

692899

DPP4
Dipeptidyl peptidase 4

1

0

High-throughput

0.493

High

931353

G3BP1
Ras GTPase-activating protein-binding protein 1

1

1

High-throughput

0.489

High

931367

NOMO1
BOS complex subunit NOMO1

1

1

High-throughput

0.489

High

931412

COQ8A
Atypical kinase COQ8A, mitochondrial

1

1

High-throughput

0.489

High

931429

RN185
E3 ubiquitin-protein ligase RNF185

1

2

High-throughput

0.489

High

931444

UN93B
Protein unc-93 homolog B1

1

1

High-throughput

0.489

High

931445

TMX4
Thioredoxin-related transmembrane protein 4

1

2

High-throughput

0.489

High

931463

CHPF2
Chondroitin sulfate glucuronyltransferase

1

3

High-throughput

0.489

High

641929

CD9
CD9 antigen

1

7

High-throughput

0.484

High

798897

BRCA1
Breast cancer type 1 susceptibility protein

1

3

High-throughput

0.481

High

126521

RHOD
Rho-related GTP-binding protein RhoD

1

16

High-throughput

0.479

High

164292

NRP1
Neuropilin-1

1

1

High-throughput

0.479

High

178224

NPC1
NPC intracellular cholesterol transporter 1

1

3

High-throughput

0.479

High

218002

TGON2
Trans-Golgi network integral membrane protein 2

1

1

High-throughput

0.479

High

318680

RHBT1
Rho-related BTB domain-containing protein 1

1

10

High-throughput

0.479

High

343843

SEM4F
Semaphorin-4F

1

2

High-throughput

0.479

High

363030

EGFR
Epidermal growth factor receptor

1

3

High-throughput

0.479

High

458344

ADRB2
Beta-2 adrenergic receptor

1

1

High-throughput

0.479

High

541410

FGFR1
Fibroblast growth factor receptor 1

1

4

High-throughput

0.479

High

580952

RAC2
Ras-related C3 botulinum toxin substrate 2

1

9

High-throughput

0.479

High

599565

STMN1
Stathmin

1

1

High-throughput

0.479

High

601221

RHOQ
Rho-related GTP-binding protein RhoQ

1

13

High-throughput

0.479

High

766349

PHB1
Prohibitin 1

1

3

High-throughput

0.479

High

774232

BASI
Basigin

1

1

High-throughput

0.479

High

931329

RAC3
Ras-related C3 botulinum toxin substrate 3

1

11

High-throughput

0.479

High

931330

CDC42
Cell division control protein 42 homolog

1

11

High-throughput

0.479

High

931331

RHOA
Transforming protein RhoA

1

11

High-throughput

0.479

High

931332

RND3
Rho-related GTP-binding protein RhoE

1

14

High-throughput

0.479

High

931335

RHOB
Rho-related GTP-binding protein RhoB

1

12

High-throughput

0.479

High

931337

RAC1
Ras-related C3 botulinum toxin substrate 1

1

11

High-throughput

0.479

High

931340

RHOG
Rho-related GTP-binding protein RhoG

1

9

High-throughput

0.479

High

931343

IFM3
Interferon-induced transmembrane protein 3

1

1

High-throughput

0.479

High

931345

EWS
RNA-binding protein EWS

1

1

High-throughput

0.479

High

931369

RHOH
Rho-related GTP-binding protein RhoH

1

12

High-throughput

0.479

High

931391

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

931409

SERB1
SERPINE1 mRNA-binding protein 1

1

1

High-throughput

0.479

High

931418

SCRB1
Scavenger receptor class B member 1

1

3

High-throughput

0.479

High

931436

ABCA3
Phospholipid-transporting ATPase ABCA3

1

1

High-throughput

0.479

High

931440

TRI55
Tripartite motif-containing protein 55

1

3

High-throughput

0.479

High

931442

SEM4C
Semaphorin-4C

1

2

High-throughput

0.479

High

931447

RHOJ
Rho-related GTP-binding protein RhoJ

1

13

High-throughput

0.479

High

931448

PKHA4
Pleckstrin homology domain-containing family A member 4

1

2

High-throughput

0.479

High

931453

RHOF
Rho-related GTP-binding protein RhoF

1

14

High-throughput

0.479

High

931455

E41L5
Band 4.1-like protein 5

1

2

High-throughput

0.479

High

931467

UBQL2
Ubiquilin-2

1

2

High-throughput

0.479

High

931432

NLRP3
NACHT, LRR and PYD domains-containing protein 3

1

0

Small-scale

0.460

High

350226

FADS2
Acyl-CoA 6-desaturase

1

0

High-throughput

0.458

High

488755

FURIN
Furin

1

0

High-throughput

0.458

High

536825

HSP7C
Heat shock cognate 71 kDa protein

1

0

High-throughput

0.458

High

550941

PCNA
Proliferating cell nuclear antigen

1

0

High-throughput

0.458

High

566601

PDIA4
Protein disulfide-isomerase A4

1

0

High-throughput

0.458

High

568220

PLST
Plastin-3

1

0

Small-scale

0.458

High

620225

NUCL
Nucleolin

1

0

High-throughput

0.458

High

640822

VDAC1
Non-selective voltage-gated ion channel VDAC1

1

0

High-throughput

0.458

High

642748

KCNA3
Potassium voltage-gated channel subfamily A member 3

1

0

High-throughput

0.458

High

710140

EPHA2
Ephrin type-A receptor 2

1

0

High-throughput

0.458

High

931328

ACTB
Actin, cytoplasmic 1

1

0

High-throughput

0.458

High

931385

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

931390

TBA1A
Tubulin alpha-1A chain

1

0

High-throughput

0.458

High

931392

GALT7
N-acetylgalactosaminyltransferase 7

1

0

High-throughput

0.458

High

931403

PCD20
Protocadherin-20

1

0

High-throughput

0.458

High

931414

MYBPP
MYCBP-associated protein

1

0

High-throughput

0.458

High

931419

ABHD3
Phospholipase ABHD3

1

0

High-throughput

0.458

High

931446

DNJC5
DnaJ homolog subfamily C member 5

1

0

High-throughput

0.458

High

211124

CTR4
Cationic amino acid transporter 4

1

4

High-throughput

0.445

High

349398

TSN15
Tetraspanin-15

1

6

High-throughput

0.445

High

529416

TAU
Microtubule-associated protein tau

1

7

High-throughput

0.445

High

538556

GTR1
Solute carrier family 2, facilitated glucose transporter member 1

1

4

High-throughput

0.445

High

722426

CTR1
High affinity cationic amino acid transporter 1

1

4

High-throughput

0.445

High

834940

S19A1
Reduced folate transporter

1

1

High-throughput

0.445

High

912647

CTR2
Cationic amino acid transporter 2

1

4

High-throughput

0.445

High

931325

S12A2
Solute carrier family 12 member 2

1

1

High-throughput

0.445

High

931327

CD81
CD81 antigen

1

7

High-throughput

0.445

High

931333

TSN5
Tetraspanin-5

1

7

High-throughput

0.445

High

931358

CAC1C
Voltage-dependent L-type calcium channel subunit alpha-1C

1

5

High-throughput

0.445

High

931361

NTCP
Hepatic sodium/bile acid cotransporter

1

1

High-throughput

0.445

High

931384

PKHA7
Pleckstrin homology domain-containing family A member 7

1

3

High-throughput

0.445

High

931410

MOT11
Monocarboxylate transporter 11

1

2

High-throughput

0.445

High

931411

MFSD8
Major facilitator superfamily domain-containing protein 8

1

1

High-throughput

0.445

High

931438

S46A2
Solute carrier family 46 member 2

1

3

High-throughput

0.445

High

931441

S19A3
Thiamine transporter 2

1

1

High-throughput

0.445

High

931457

SO1B3
Solute carrier organic anion transporter family member 1B3

1

1

High-throughput

0.445

High

931352

UBP4
Ubiquitin carboxyl-terminal hydrolase 4

1

2

Small-scale

0.439

High

931360

TRI14
Tripartite motif-containing protein 14

1

3

High-throughput

0.439

High

931388

PAXI1
PAX-interacting protein 1

1

1

High-throughput

0.439

High

931435

BARD1
BRCA1-associated RING domain protein 1

1

2

High-throughput

0.439

High

931398

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

0

Small-scale

0.438

High

125351

LEG9
Galectin-9

1

2

High-throughput

0.437

High

293424

CD123
Translation initiation factor eIF2 assembly protein

1

1

High-throughput

0.437

High

315331

RECQ4
ATP-dependent DNA helicase Q4

1

1

High-throughput

0.437

High

588302

RFA2
Replication protein A 32 kDa subunit

1

1

High-throughput

0.437

High

634089

COX5A
Cytochrome c oxidase subunit 5A, mitochondrial

1

1

High-throughput

0.437

High

695030

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

1

High-throughput

0.437

High

767790

RFA3
Replication protein A 14 kDa subunit

1

1

High-throughput

0.437

High

907347

UBP11
Ubiquitin carboxyl-terminal hydrolase 11

1

2

High-throughput

0.437

High

931338

RNF4
E3 ubiquitin-protein ligase RNF4

1

1

High-throughput

0.437

High

931349

DHX9
ATP-dependent RNA helicase A

1

1

Small-scale

0.437

High

931357

APR
Phorbol-12-myristate-13-acetate-induced protein 1

1

1

High-throughput

0.437

High

931383

VIR
Protein virilizer homolog

1

1

High-throughput

0.437

High

931387

TRI67
Tripartite motif-containing protein 67

1

5

High-throughput

0.437

High

931399

S15A3
Solute carrier family 15 member 3

1

3

High-throughput

0.437

High

931408

RN149
E3 ubiquitin-protein ligase RNF149

1

2

High-throughput

0.437

High

931422

TM9S4
Transmembrane 9 superfamily member 4

1

4

High-throughput

0.437

High

931426

MFRN2
Mitoferrin-2

1

2

High-throughput

0.437

High

931431

SNX27
Sorting nexin-27

1

2

High-throughput

0.437

High

931465

ZRAN1
Ubiquitin thioesterase ZRANB1

1

1

High-throughput

0.437

High

931472

POMT1
Protein O-mannosyl-transferase 1

1

2

High-throughput

0.437

High

720385

SC6A1
Sodium- and chloride-dependent GABA transporter 1

1

0

High-throughput

0.426

High

931375

SC5AC
Sodium-coupled monocarboxylate transporter 2

1

0

High-throughput

0.426

High

931396

S22A9
Organic anion transporter 7

1

0

High-throughput

0.426

High

931401

LAT4
Large neutral amino acids transporter small subunit 4

1

0

High-throughput

0.426

High

931415

S26A7
Anion exchange transporter

1

0

High-throughput

0.426

High

931460

S17A5
Sialin

1

0

High-throughput

0.426

High

931464

RHCG
Ammonium transporter Rh type C

1

0

High-throughput

0.426

High

97238

E9PS44
Interferon induced transmembrane protein 3

1

1

High-throughput

0.407

High

104129

F5H1C8
Solute carrier family 15 member 3

1

3

High-throughput

0.407

High

931473

X6RFA8
Solute carrier family 25 member 28

1

2

High-throughput

0.407

High

931342

REEP5
Receptor expression-enhancing protein 5

4

0

High-throughput

0.360

High

931443

LNP
Endoplasmic reticulum junction formation protein lunapark

4

0

High-throughput

0.360

High

931382

MANEL
Glycoprotein endo-alpha-1,2-mannosidase-like protein

3

0

High-throughput

0.347

High

931386

TMPPE
Transmembrane protein with metallophosphoesterase domain

3

0

High-throughput

0.347

High

931406

F241A
Uncharacterized protein FAM241A

3

0

High-throughput

0.347

High

931417

PIGO
GPI ethanolamine phosphate transferase 3, catalytic subunit

3

0

High-throughput

0.347

High

931427

F241B
Protein FAM241B

3

0

High-throughput

0.347

High

931449

ALG9
Alpha-1,2-mannosyltransferase ALG9

3

0

High-throughput

0.347

High

931434

CGRF1
Cell growth regulator with RING finger domain protein 1

2

0

High-throughput

0.328

High

931462

IMPA3
Golgi-resident adenosine 3',5'-bisphosphate 3'-phosphatase

2

0

High-throughput

0.318

High

931377

CTXN3
Cortexin-3

2

0

High-throughput

0.316

High

130414

SPT5H
Transcription elongation factor SPT5

1

0

High-throughput

0.279

Low

931359

UBE4A
Ubiquitin conjugation factor E4 A

1

0

High-throughput

0.279

Low

931374

MK06
Mitogen-activated protein kinase 6

1

0

High-throughput

0.279

Low

931405

PAF1
RNA polymerase II-associated factor 1 homolog

1

0

High-throughput

0.279

Low

931425

CCD47
PAT complex subunit CCDC47

1

0

High-throughput

0.279

Low

931433

CP2S1
Cytochrome P450 2S1

1

0

High-throughput

0.279

Low

931470

SNX5
Sorting nexin-5

1

0

High-throughput

0.279

Low

931366

PEA15
Astrocytic phosphoprotein PEA-15

1

0

Small-scale

0.251

Low

931421

BAALC
Brain and acute leukemia cytoplasmic protein

1

0

Small-scale

0.251

Low

931452

RENT2
Regulator of nonsense transcripts 2

1

0

High-throughput

0.251

Low

60709

F234B
Protein FAM234B

1

0

High-throughput

0.249

Low

606496

CEBPB
CCAAT/enhancer-binding protein beta

1

0

High-throughput

0.249

Low

617494

ATP5J
ATP synthase peripheral stalk subunit F6, mitochondrial

1

0

High-throughput

0.249

Low

773463

COPB2
Coatomer subunit beta'

1

0

High-throughput

0.249

Low

931336

RL8
Large ribosomal subunit protein uL2

1

0

High-throughput

0.249

Low

931351

ACACA
Acetyl-CoA carboxylase 1

1

0

High-throughput

0.249

Low

931355

BIRC3
Baculoviral IAP repeat-containing protein 3

1

0

High-throughput

0.249

Low

931362

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.249

Low

931363

HERP1
Homocysteine-responsive endoplasmic reticulum-resident ubiquitin-like domain member 1 protein

1

0

High-throughput

0.249

Low

931368

KS6A2
Ribosomal protein S6 kinase alpha-2

1

0

High-throughput

0.249

Low

931371

E2F4
Transcription factor E2F4

1

0

High-throughput

0.249

Low

931379

MIDN
Midnolin

1

0

High-throughput

0.249

Low

931380

TM41B
Transmembrane protein 41B

1

0

High-throughput

0.249

Low

931381

DOP1A
Protein DOP1A

1

0

High-throughput

0.249

Low

931389

XIRP1
Xin actin-binding repeat-containing protein 1

1

0

High-throughput

0.249

Low

931394

ZN598
E3 ubiquitin-protein ligase ZNF598

1

0

High-throughput

0.249

Low

931395

ARMC8
Armadillo repeat-containing protein 8

1

0

High-throughput

0.249

Low

931400

K2013
Uncharacterized protein KIAA2013

1

0

High-throughput

0.249

Low

931407

PMGT2
Protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2

1

0

High-throughput

0.249

Low

931416

PXYP1
2-phosphoxylose phosphatase 1

1

0

High-throughput

0.249

Low

931428

TMA16
Translation machinery-associated protein 16

1

0

High-throughput

0.249

Low

931430

TECT2
Tectonic-2

1

0

High-throughput

0.249

Low

931450

EGLN3
Prolyl hydroxylase EGLN3

1

0

High-throughput

0.249

Low

931451

SFXN1
Sideroflexin-1

1

0

High-throughput

0.249

Low

931454

NMRL1
NmrA-like family domain-containing protein 1

1

0

High-throughput

0.249

Low

931456

EMC7
Endoplasmic reticulum membrane protein complex subunit 7

1

0

High-throughput

0.249

Low

931458

INO1
Inositol-3-phosphate synthase 1

1

0

High-throughput

0.249

Low

931354

CTBP1
C-terminal-binding protein 1

1

0

High-throughput

0.232

Low

931364

MD2BP
MAD2L1-binding protein

1

0

High-throughput

0.232

Low

931402

MFD4A
Major facilitator superfamily domain-containing protein 4A

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025