HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: LAR1B (Q659C4)
La-related protein 1B (La ribonucleoprotein domain family member 1B) (La ribonucleoprotein domain family member 2) (La-related protein 2)
Gene: LARP1B

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005829 - cytosol
Homologous interactions	11

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 914
+	Hs
		1041847 CUL3_HUMAN (1-768): 0: 951: 100.00		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1043415 CUL4B_HUMAN (5-768): 0: 779: 36.77		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1041054 CUL1_HUMAN (18-768): 0: 707: 30.57		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1041367 CUL2_HUMAN (30-768): 0: 672: 26.17		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1162634 CUL5_HUMAN (25-768): 0: 597: 23.77		LARP1_HUMAN (3-883): 0: 773: 58.95
+	Hs
		1041882 CUL3_HUMAN (1-768): 0: 951: 100.00		LARP4_HUMAN (114-703): 1.5e-97: 323: 13.29
+	Hs
		1042183 CUL3_HUMAN (1-768): 0: 951: 100.00		LAR4B_HUMAN (95-701): 2.54e-81: 280: 10.36
+	Hs
		403219 CUL3_HUMAN (1-768): 0: 951: 100.00		LA_HUMAN (215-628): 1.98e-59: 210: 17.78
+	Hs
		403220 CUL4B_HUMAN (5-768): 0: 779: 36.77		LA_HUMAN (215-628): 1.98e-59: 210: 17.78
+	Hs
		403217 CUL1_HUMAN (18-768): 0: 707: 30.57		LA_HUMAN (215-628): 1.98e-59: 210: 17.78
+	Hs
		403218 CUL2_HUMAN (30-768): 0: 672: 26.17		LA_HUMAN (215-628): 1.98e-59: 210: 17.78