HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: PHLP2 (Q6ZVD8)
PH domain leucine-rich repeat-containing protein phosphatase 2 (EC 3.1.3.16) (PH domain leucine-rich repeat-containing protein phosphatase-like) (PHLPP-like)
Gene: PHLPP2

Species: Homo sapiens

Source: biogrid

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	28859855
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0072686 - mitotic spindle
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1323
+	Hs
		1042425 CUL3_HUMAN (1-768): 0: 951: 100.00		LRRC1_HUMAN (513-772): 7.92e-14: 77.8: 29.83
+	Hs
		1042318 CUL3_HUMAN (1-768): 0: 951: 100.00		LRRC7_HUMAN (448-746): 2.05e-13: 77.4: 28.89
+	Hs
		1041552 CUL3_HUMAN (1-768): 0: 951: 100.00		SCRIB_HUMAN (438-732): 2.62e-12: 73.9: 29.00
+	Hs
		1042341 CUL3_HUMAN (1-768): 0: 951: 100.00		ERBIN_HUMAN (461-746): 7.29e-10: 65.9: 24.75
+	Hs
		1043528 CUL4B_HUMAN (5-768): 0: 779: 36.77		ERBIN_HUMAN (461-746): 7.29e-10: 65.9: 24.75