HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: KNDC1 (Q76NI1)
Kinase non-catalytic C-lobe domain-containing protein 1 (KIND domain-containing protein 1) (Cerebral protein 9) (Protein very KIND) (v-KIND) (Ras-GEF domain-containing family member 2)
Gene: KNDC1

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1749
+	Hs
		1043075 CUL4A_HUMAN (10-768): 0: 791: 38.32		KNDC1_HUMAN (1-1749): 0: 2199: 100.00
+	Hs
		1042610 CUL3_HUMAN (1-768): 0: 951: 100.00		KI13B_HUMAN (505-933): 8.24e-22: 105: 15.73
+	Hs
		1042076 CUL3_HUMAN (1-768): 0: 951: 100.00		KMT2C_HUMAN (556-1109): 2.75e-16: 87.6: 12.08
+	Hs
		1042150 CUL3_HUMAN (1-768): 0: 951: 100.00		ATX2L_HUMAN (269-1039): 2.39e-13: 77.6: 11.22
+	Hs
		1042196 CUL3_HUMAN (1-768): 0: 951: 100.00		CBP_HUMAN (760-1120): 2.72e-12: 74.6: 11.65
+	Hs
		1042290 CUL3_HUMAN (1-768): 0: 951: 100.00		CHAP1_HUMAN (369-815): 1.38e-11: 71.9: 8.73
+	Hs
		867096 CUL3_HUMAN (1-768): 0: 951: 100.00		SC24C_HUMAN (702-1037): 5.75e-10: 66.7: 12.92
+	Hs
		979894 CUL3_HUMAN (1-768): 0: 951: 100.00		IF4G1_HUMAN (375-955): 3.04e-09: 64.5: 10.22
+	Dm
		1359795 Q9V475_DROME (2-768): 0: 861: 68.77		Q9VLS7_DROME (391-1105): 1.91e-13: 78.4: 11.73
+	Hs
		979895 CUL4B_HUMAN (5-768): 0: 779: 36.77		IF4G1_HUMAN (375-955): 3.04e-09: 64.5: 10.22