Protein: ARB1
ABC transporter ATP-binding protein ARB1 (EC 3.6.5.-) (ATP-binding cassette protein involved in ribosome biogenesis 1)

Gene: ARB1
Organism: Saccharomyces cerevisiae S288C
Interactions: 137
UniProt ID: P40024

Gene Ontology (top 5):
GO:0000056 - ribosomal small subunit export from nucleus
GO:0005524 - ATP binding
GO:0005634 - nucleus
GO:0005737 - cytoplasm
GO:0006515 - protein quality control for misfolded or incompletely synthesized proteins

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

817276

CBK1
Serine/threonine-protein kinase CBK1

2

1

Small-scale

0.767

High

817265

PTK2
Serine/threonine-protein kinase PTK2/STK2

1

3

High-throughput

0.691

High

817278

ARK1
Actin-regulating kinase 1

1

2

High-throughput

0.691

High

813981

IF2P
Eukaryotic translation initiation factor 5B

3

6

Small-scale

0.662

High

602475

PHO85
Cyclin-dependent protein kinase PHO85

1

1

High-throughput

0.647

High

800707

RCK1
Serine/threonine-protein kinase RCK1

1

3

High-throughput

0.647

High

817259

PRK1
Actin-regulating kinase PRK1

1

2

High-throughput

0.647

High

464601

PBS2
MAP kinase kinase PBS2

1

2

High-throughput

0.618

High

597468

EF3A
Elongation factor 3A

1

6

Small-scale

0.618

High

817296

NEW1
[NU+] prion formation protein 1

1

6

High-throughput

0.618

High

817287

ARX1
Probable metalloprotease ARX1

3

0

Small-scale

0.616

High

735501

IRE1
Serine/threonine-protein kinase/endoribonuclease IRE1

1

0

High-throughput

0.614

High

758299

HSL1
Probable serine/threonine-protein kinase HSL1

1

0

High-throughput

0.614

High

435123

RS3
Small ribosomal subunit protein uS3

2

3

High-throughput

0.611

High

438706

SC160
Protein SCP160

2

4

Small-scale

0.584

High

444527

DED1
ATP-dependent RNA helicase DED1

2

1

Small-scale

0.584

High

817260

DSN1
Kinetochore-associated protein DSN1

2

3

High-throughput

0.584

High

817264

RPN11
Ubiquitin carboxyl-terminal hydrolase RPN11

2

6

High-throughput

0.584

High

817288

VMS1
tRNA endonuclease VMS1

2

2

Small-scale

0.584

High

817297

TMA46
Translation machinery-associated protein 46

2

3

Small-scale

0.584

High

427296

RLA0
Large ribosomal subunit protein uL10

1

2

High-throughput

0.575

High

526791

HSP72
Heat shock protein SSA2

2

7

Small-scale

0.571

High

674651

RS2
Small ribosomal subunit protein uS5

2

2

High-throughput

0.571

High

817263

VATH
V-type proton ATPase subunit H

2

1

High-throughput

0.567

High

601057

RL8A
Large ribosomal subunit protein eL8A

2

1

Small-scale

0.558

High

817282

RL6A
Large ribosomal subunit protein eL6A

2

2

Small-scale

0.558

High

524067

HSP71
Heat shock protein SSA1

2

7

High-throughput

0.552

High

545010

SSB1
Ribosome-associated molecular chaperone SSB1

2

9

High-throughput

0.552

High

570032

RL3
Large ribosomal subunit protein uL3

1

2

High-throughput

0.536

High

802863

DBP8
ATP-dependent RNA helicase DBP8

1

7

High-throughput

0.536

High

689046

RL16A
Large ribosomal subunit protein uL13A

2

4

Small-scale

0.533

High

817272

EIF2A
Eukaryotic translation initiation factor 2A

2

3

Small-scale

0.533

High

753395

RS3A1
Small ribosomal subunit protein eS1A

2

2

High-throughput

0.521

High

817289

PLM2
Protein PLM2

1

0

High-throughput

0.518

High

518301

IF4A
ATP-dependent RNA helicase eIF4A

1

3

High-throughput

0.515

High

383312

RL28
Large ribosomal subunit protein uL15

1

0

High-throughput

0.513

High

433216

RL17A
Large ribosomal subunit protein uL22A

1

0

High-throughput

0.513

High

712582

RL8B
Large ribosomal subunit protein eL8B

1

1

High-throughput

0.489

High

623865

MYO2
Myosin-2

1

1

Small-scale

0.481

High

149789

RS9A
Small ribosomal subunit protein uS4A

1

2

High-throughput

0.479

High

392791

HSP82
ATP-dependent molecular chaperone HSP82

1

9

High-throughput

0.479

High

394596

EF1A
Elongation factor 1-alpha

1

3

High-throughput

0.479

High

419747

H2A2
Histone H2A.2

1

3

High-throughput

0.479

High

430859

ERF3
Eukaryotic peptide chain release factor GTP-binding subunit

1

5

High-throughput

0.479

High

435991

RS13
Small ribosomal subunit protein uS15

1

2

High-throughput

0.479

High

452577

C1TC
C-1-tetrahydrofolate synthase, cytoplasmic

1

1

Small-scale

0.479

High

482024

C1TM
C-1-tetrahydrofolate synthase, mitochondrial

1

1

Small-scale

0.479

High

514659

RS18A
Small ribosomal subunit protein uS13A

1

3

High-throughput

0.479

High

558740

CAF20
Cap-associated protein CAF20

1

3

High-throughput

0.479

High

579463

HSC82
ATP-dependent molecular chaperone HSC82

1

9

High-throughput

0.479

High

592278

VATB
V-type proton ATPase subunit B

1

1

Small-scale

0.479

High

647122

RPC2
DNA-directed RNA polymerase III subunit RPC2

1

6

High-throughput

0.479

High

670756

SIS1
Protein SIS1

1

8

High-throughput

0.479

High

676031

MAS5
Mitochondrial protein import protein MAS5

1

6

Small-scale

0.479

High

679726

CDC48
Cell division control protein 48

1

4

High-throughput

0.479

High

689483

RS7A
Small ribosomal subunit protein eS7A

1

3

High-throughput

0.479

High

707201

TF2B
Transcription initiation factor IIB

1

4

High-throughput

0.479

High

709785

BMH1
Protein BMH1

1

1

High-throughput

0.479

High

727058

HS104
Heat shock protein 104

1

4

High-throughput

0.479

High

739379

ZUO1
Zuotin

1

6

Small-scale

0.479

High

747880

SMY2
Protein SMY2

1

2

High-throughput

0.479

High

750674

PRS6A
26S proteasome regulatory subunit 6A

1

6

High-throughput

0.479

High

778354

RS27A
Small ribosomal subunit protein eS27A

1

2

High-throughput

0.479

High

779241

CENPA
Histone H3-like centromeric protein CSE4

1

7

High-throughput

0.479

High

782165

LAS1
Protein LAS1

1

2

Small-scale

0.479

High

796581

EIF3A
Eukaryotic translation initiation factor 3 subunit A

1

2

Small-scale

0.479

High

802628

YHI0
Putative proline--tRNA ligase YHR020W

1

6

High-throughput

0.479

High

803556

RPN1
26S proteasome regulatory subunit RPN1

1

3

High-throughput

0.479

High

806722

RPN10
26S proteasome regulatory subunit RPN10

1

4

High-throughput

0.479

High

807190

IF1A
Eukaryotic translation initiation factor 1A

1

3

High-throughput

0.479

High

812043

DHH1
ATP-dependent RNA helicase DHH1

1

3

High-throughput

0.479

High

817258

TM108
Protein TMA108

1

5

High-throughput

0.479

High

817266

RS12
Small ribosomal subunit protein eS12

1

4

High-throughput

0.479

High

817270

LSG1
Large subunit GTPase 1

1

3

Small-scale

0.479

High

817273

PESC
Pescadillo homolog

1

2

High-throughput

0.479

High

817281

RS15
Small ribosomal subunit protein uS19

1

3

High-throughput

0.479

High

817283

ESP1
Separin

1

2

High-throughput

0.479

High

817284

SVL3
Styryl dye vacuolar localization protein 3

1

1

High-throughput

0.479

High

817285

TOM1
E3 ubiquitin-protein ligase TOM1

1

5

High-throughput

0.479

High

817286

CLU
Clustered mitochondria protein 1

1

1

Small-scale

0.479

High

817291

MMS22
E3 ubiquitin-protein ligase substrate receptor MMS22

1

1

High-throughput

0.479

High

817292

TFC6
Transcription factor tau 91 kDa subunit

1

2

High-throughput

0.479

High

817293

SGO1
Shugoshin

1

1

High-throughput

0.479

High

817298

RIO1
Serine/threonine-protein kinase RIO1

1

2

High-throughput

0.479

High

817299

DBP10
ATP-dependent RNA helicase DBP10

1

8

High-throughput

0.479

High

817300

NOP56
Nucleolar protein 56

1

5

Small-scale

0.479

High

817302

IF6
Eukaryotic translation initiation factor 6

1

1

Small-scale

0.479

High

450593

FAS1
Fatty acid synthase subunit beta

1

0

Small-scale

0.458

High

512084

RS4A
Small ribosomal subunit protein eS4A

1

0

High-throughput

0.458

High

645432

XRN1
5'-3' exoribonuclease 1

1

0

High-throughput

0.458

High

751409

CBF5
H/ACA ribonucleoprotein complex subunit CBF5

1

0

Small-scale

0.458

High

805592

LSM12
Protein LSM12

1

0

Small-scale

0.458

High

817274

TR112
Multifunctional methyltransferase subunit TRM112

1

0

Small-scale

0.458

High

817279

TMA20
Translation machinery-associated protein 20

1

0

High-throughput

0.458

High

817290

HEL2
E3 ubiquitin-protein ligase HEL2

1

0

High-throughput

0.458

High

432596

RL7A
Large ribosomal subunit protein uL30A

1

5

High-throughput

0.445

High

741657

HSP7F
Heat shock protein homolog SSE1

1

12

High-throughput

0.445

High

810693

TCPB
T-complex protein 1 subunit beta

1

1

High-throughput

0.445

High

817257

SSB2
Ribosome-associated molecular chaperone SSB2

1

9

High-throughput

0.445

High

817267

RL4B
Large ribosomal subunit protein uL4B

1

2

High-throughput

0.445

High

811208

PCF11
Protein PCF11

1

0

High-throughput

0.438

High

383723

RS17A
Small ribosomal subunit protein eS17A

1

2

High-throughput

0.437

High

410160

RL25
Large ribosomal subunit protein uL23

1

3

High-throughput

0.437

High

433667

RL26A
Large ribosomal subunit protein uL24A

1

3

High-throughput

0.437

High

441933

RS14A
Small ribosomal subunit protein uS11A

1

3

High-throughput

0.437

High

455088

RS19A
Small ribosomal subunit protein eS19A

1

3

High-throughput

0.437

High

455410

RS19B
Small ribosomal subunit protein eS19B

1

3

Small-scale

0.437

High

456407

ILVB
Acetolactate synthase catalytic subunit, mitochondrial

1

1

Small-scale

0.437

High

502733

RS21A
Small ribosomal subunit protein eS21A

1

1

Small-scale

0.437

High

503068

RS22A
Small ribosomal subunit protein uS8A

1

3

High-throughput

0.437

High

504237

RL31A
Large ribosomal subunit protein eL31A

1

2

High-throughput

0.437

High

512465

RS6A
Small ribosomal subunit protein eS6A

1

3

High-throughput

0.437

High

513031

RS8A
Small ribosomal subunit protein eS8A

1

2

High-throughput

0.437

High

747392

RSSA1
Small ribosomal subunit protein uS2A

1

2

High-throughput

0.437

High

754285

DCA13
Protein SOF1

1

4

Small-scale

0.437

High

781201

RL14A
Large ribosomal subunit protein eL14A

1

1

Small-scale

0.437

High

812332

LAA1
AP-1 accessory protein LAA1

1

4

High-throughput

0.437

High

817256

UTP7
U3 small nucleolar RNA-associated protein 7

1

1

Small-scale

0.437

High

817261

RLP7
Ribosome biogenesis protein RLP7

1

5

High-throughput

0.437

High

817262

RL33B
Large ribosomal subunit protein eL33B

1

1

Small-scale

0.437

High

817277

SAM50
Sorting assembly machinery 50 kDa subunit

1

1

High-throughput

0.437

High

817280

NUM1
Nuclear migration protein NUM1

1

4

High-throughput

0.437

High

817294

RS10A
Small ribosomal subunit protein eS10A

1

3

High-throughput

0.437

High

817295

AP3D
AP-3 complex subunit delta

1

3

High-throughput

0.437

High

817301

NOP58
Nucleolar protein 58

1

5

Small-scale

0.437

High

817303

RS21B
Small ribosomal subunit protein eS21B

1

1

Small-scale

0.437

High

817268

IMDH3
Inosine-5'-monophosphate dehydrogenase 3

1

0

High-throughput

0.426

High

817269

PRP43
Pre-mRNA-splicing factor ATP-dependent RNA helicase PRP43

1

0

High-throughput

0.426

High

514295

RL12B
Large ribosomal subunit protein uL11B

2

0

High-throughput

0.305

High

427703

RLA2
Large ribosomal subunit protein P2A

1

0

Small-scale

0.249

Low

511206

RL20B
Large ribosomal subunit protein eL20B

1

0

High-throughput

0.249

Low

515263

RL35A
Large ribosomal subunit protein uL29A

1

0

Small-scale

0.249

Low

642141

IDHP
Isocitrate dehydrogenase [NADP], mitochondrial

1

0

Small-scale

0.249

Low

720924

SEC1
Protein transport protein SEC1

1

0

Small-scale

0.249

Low

793079

ATPG
ATP synthase subunit gamma, mitochondrial

1

0

Small-scale

0.249

Low

817271

MNP1
Large ribosomal subunit protein bL12m

1

0

Small-scale

0.249

Low

817275

RM19
Large ribosomal subunit protein uL11m

1

0

Small-scale

0.249

Low


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Last updated: 11Aug2025