HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: RUFY3 (Q7L099)
Protein RUFY3 (RUN and FYVE domain-containing protein 3) (Rap2-interacting protein x) (RIPx) (Single axon-regulated protein) (Singar)
Gene: RUFY3

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0016020 - membrane
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 469
+	Hs
		1042352 CUL3_HUMAN (1-768): 0: 951: 100.00		RUFY1_HUMAN (60-467): 1.53e-71: 241: 55.21
+	Hs
		1042155 CUL3_HUMAN (1-768): 0: 951: 100.00		RUFY2_HUMAN (66-467): 1.62e-68: 231: 60.34
+	Hs
		725157 CUL3_HUMAN (1-768): 0: 951: 100.00		MYH10_HUMAN (249-467): 4.89e-42: 162: 15.53
+	Hs
		724816 CUL3_HUMAN (1-768): 0: 951: 100.00		MYH9_HUMAN (236-467): 2.43e-34: 139: 15.09
+	Hs
		1041911 CUL3_HUMAN (1-768): 0: 951: 100.00		MYH14_HUMAN (291-467): 8.08e-14: 76.4: 12.33
+	Hs
		725158 CUL4A_HUMAN (10-768): 0: 791: 38.32		MYH10_HUMAN (249-467): 4.89e-42: 162: 15.53
+	Hs
		725156 CUL1_HUMAN (18-768): 0: 707: 30.57		MYH10_HUMAN (249-467): 4.89e-42: 162: 15.53
+	Hs
		724815 CUL1_HUMAN (18-768): 0: 707: 30.57		MYH9_HUMAN (236-467): 2.43e-34: 139: 15.09
+	Hs
		1025283 CUL2_HUMAN (30-768): 0: 672: 26.17		LIPA1_HUMAN (52-469): 7.69e-43: 164: 15.28
+	Hs
		502913 CUL1_HUMAN (18-768): 0: 707: 30.57		MYH3_HUMAN (181-465): 5.86e-09: 60.6: 11.71