HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: SPART (Q8N0X7)
Spartin (Spastic paraplegia 20 protein) (Trans-activated by hepatitis C virus core protein 1)
Gene: SPART

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0031625 - ubiquitin protein ligase binding
Homologous interactions	12

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 666
+	Hs
		265409 CUL3_HUMAN (1-768): 0: 951: 100.00		KTNA1_HUMAN (25-429): 1.48e-105: 331: 11.52
+	Hs
		874907 CUL3_HUMAN (1-768): 0: 951: 100.00		TERA_HUMAN (172-509): 3.81e-74: 256: 10.53
+	Hs
		1042836 CUL3_HUMAN (1-768): 0: 951: 100.00		VPS4A_HUMAN (181-414): 5.75e-41: 157: 10.04
+	Hs
		260139 CUL3_HUMAN (1-768): 0: 951: 100.00		VPS4B_HUMAN (181-414): 1.09e-40: 156: 9.32
+	Hs
		1041244 CUL1_HUMAN (18-768): 0: 707: 30.57		SPAST_HUMAN (9-458): 7.59e-112: 351: 16.94
+	Hs
		874908 CUL4A_HUMAN (10-768): 0: 791: 38.32		TERA_HUMAN (172-509): 3.81e-74: 256: 10.53
+	Hs
		874909 CUL4B_HUMAN (5-768): 0: 779: 36.77		TERA_HUMAN (172-509): 3.81e-74: 256: 10.53
+	Hs
		874905 CUL1_HUMAN (18-768): 0: 707: 30.57		TERA_HUMAN (172-509): 3.81e-74: 256: 10.53
+	Hs
		874906 CUL2_HUMAN (30-768): 0: 672: 26.17		TERA_HUMAN (172-509): 3.81e-74: 256: 10.53
+	Dm
		1097193 CUL1_DROME (29-768): 0: 669: 27.49		TERA_DROME (230-649): 6.1e-71: 247: 9.15
+	Hs
		875192 CUL5_HUMAN (25-768): 0: 597: 23.77		TERA_HUMAN (172-509): 3.81e-74: 256: 10.53
+	Sc
		636771 CDC53_YEAST (30-768): 0: 573: 22.08		CDC48_YEAST (94-430): 4.48e-72: 251: 11.83