Protein: KRT86
Keratin, type II cuticular Hb6 (Hair keratin K2.11) (Keratin-86) (K86) (Type II hair keratin Hb6) (Type-II keratin Kb26)

Gene: KRT86
Organism: Homo sapiens
Interactions: 79
UniProt ID: O43790

Gene Ontology (top 5):
GO:0005615 - extracellular space
GO:0005829 - cytosol
GO:0030280 - structural constituent of skin epidermis
GO:0031424 - keratinization
GO:0045095 - keratin filament

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

227204

K1C15
Keratin, type I cytoskeletal 15

4

20

High-throughput

0.901

High

227237

K1C39
Keratin, type I cytoskeletal 39

2

20

High-throughput

0.794

High

227191

KRT34
Keratin, type I cuticular Ha4

2

20

High-throughput

0.783

High

227192

KRT36
Keratin, type I cuticular Ha6

2

20

High-throughput

0.783

High

227193

KRT37
Keratin, type I cuticular Ha7

2

20

High-throughput

0.783

High

227194

KRT38
Keratin, type I cuticular Ha8

2

20

High-throughput

0.783

High

227197

K1C14
Keratin, type I cytoskeletal 14

2

20

High-throughput

0.783

High

227200

K1C19
Keratin, type I cytoskeletal 19

2

20

High-throughput

0.783

High

227201

K1C16
Keratin, type I cytoskeletal 16

2

20

High-throughput

0.783

High

227211

K22O
Keratin, type II cytoskeletal 2 oral

2

18

High-throughput

0.783

High

227220

KT33B
Keratin, type I cuticular Ha3-II

2

20

High-throughput

0.783

High

227221

K1H2
Keratin, type I cuticular Ha2

2

20

High-throughput

0.783

High

227227

K1H1
Keratin, type I cuticular Ha1

2

20

High-throughput

0.783

High

227236

K1C40
Keratin, type I cytoskeletal 40

2

20

High-throughput

0.783

High

227240

K1C28
Keratin, type I cytoskeletal 28

2

20

High-throughput

0.783

High

227241

K1C27
Keratin, type I cytoskeletal 27

2

20

High-throughput

0.783

High

227242

K1C25
Keratin, type I cytoskeletal 25

2

20

High-throughput

0.783

High

227254

KRT35
Keratin, type I cuticular Ha5

2

20

High-throughput

0.783

High

227229

AINX
Alpha-internexin

1

20

High-throughput

0.691

High

227199

NFM
Neurofilament medium polypeptide

1

20

High-throughput

0.618

High

227198

K2C8
Keratin, type II cytoskeletal 8

1

20

High-throughput

0.618

High

169342

HGS
Hepatocyte growth factor-regulated tyrosine kinase substrate

2

6

High-throughput

0.606

High

227217

KCC2B
Calcium/calmodulin-dependent protein kinase type II subunit beta

2

1

High-throughput

0.606

High

227219

IL16
Pro-interleukin-16 [Cleaved into: Interleukin-16

2

8

High-throughput

0.606

High

227243

CEP57
Centrosomal protein of 57 kDa

2

4

High-throughput

0.606

High

227252

SHC3
SHC-transforming protein 3

2

20

High-throughput

0.606

High

227262

GLCNE
Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase

2

2

High-throughput

0.606

High

227209

NTF2
Nuclear transport factor 2

2

0

High-throughput

0.580

High

227224

JOS1
Josephin-1

2

0

High-throughput

0.580

High

70045

CRTP1
Cysteine-rich tail protein 1

2

3

High-throughput

0.553

High

217017

MS18B
Protein Mis18-beta

2

6

High-throughput

0.553

High

227187

MABP1
Mitogen-activated protein kinase-binding protein 1

2

7

High-throughput

0.553

High

227212

CREB5
Cyclic AMP-responsive element-binding protein 5

2

4

High-throughput

0.553

High

227213

CDK18
Cyclin-dependent kinase 18

2

1

High-throughput

0.553

High

227216

MKRN3
E3 ubiquitin-protein ligase makorin-3

2

1

High-throughput

0.553

High

227230

T10IP
Testis-specific protein 10-interacting protein

2

1

High-throughput

0.553

High

227234

KANK2
KN motif and ankyrin repeat domain-containing protein 2

2

4

High-throughput

0.553

High

227239

OLIG3
Oligodendrocyte transcription factor 3

2

1

High-throughput

0.553

High

227245

CC146
Coiled-coil domain-containing protein 146

2

1

High-throughput

0.553

High

227246

ZN655
Zinc finger protein 655

2

3

High-throughput

0.553

High

227251

TEKT4
Tektin-4

2

3

High-throughput

0.553

High

227258

ZN414
Zinc finger protein 414

2

1

High-throughput

0.553

High

227261

RESF1
Retroelement silencing factor 1

2

1

High-throughput

0.553

High

227190

OFD1
Centriole and centriolar satellite protein OFD1

1

3

High-throughput

0.536

High

227205

ITPI2
Protein ITPRID2

1

2

High-throughput

0.536

High

227208

EPIPL
Epiplakin

1

20

High-throughput

0.536

High

227215

MPPA
Mitochondrial-processing peptidase subunit alpha

1

2

High-throughput

0.536

High

227226

PCM1
Pericentriolar material 1 protein

1

4

High-throughput

0.536

High

227244

UBR1
E3 ubiquitin-protein ligase UBR1

1

1

High-throughput

0.536

High

227256

EXOC4
Exocyst complex component 4

1

2

High-throughput

0.536

High

227207

MEOX2
Homeobox protein MOX-2

1

4

High-throughput

0.523

High

227189

MPPB
Mitochondrial-processing peptidase subunit beta

1

2

High-throughput

0.489

High

227214

IFFO1
Non-homologous end joining factor IFFO1

1

20

High-throughput

0.489

High

227232

PREP
Presequence protease, mitochondrial

1

4

High-throughput

0.489

High

227250

NUDT8
Mitochondrial coenzyme A diphosphatase NUDT8

1

1

High-throughput

0.489

High

227257

OMA1
Metalloendopeptidase OMA1, mitochondrial

1

1

High-throughput

0.489

High

227259

FYCO1
FYVE and coiled-coil domain-containing protein 1

1

10

High-throughput

0.489

High

227188

OBSL1
Obscurin-like protein 1

1

8

High-throughput

0.479

High

227195

EGFR
Epidermal growth factor receptor

1

6

High-throughput

0.479

High

227196

TNFA
Tumor necrosis factor

1

4

High-throughput

0.479

High

227202

CFTR
Cystic fibrosis transmembrane conductance regulator

1

16

High-throughput

0.479

High

227206

EPS15
Epidermal growth factor receptor substrate 15

1

13

High-throughput

0.479

High

227210

GRB2
Growth factor receptor-bound protein 2

1

18

High-throughput

0.479

High

227225

PLEC
Plectin

1

18

High-throughput

0.479

High

227233

OTU1
Ubiquitin thioesterase OTU1

1

6

High-throughput

0.479

High

227238

RICTR
Rapamycin-insensitive companion of mTOR

1

4

High-throughput

0.479

High

227247

NHLC2
NHL repeat-containing protein 2

1

5

High-throughput

0.479

High

227249

TNIP2
TNFAIP3-interacting protein 2

1

4

High-throughput

0.479

High

227235

A16L1
Autophagy-related protein 16-1

1

7

High-throughput

0.445

High

227203

EGR1
Early growth response protein 1

1

3

High-throughput

0.437

High

227218

DX39B
Spliceosome RNA helicase DDX39B

1

16

High-throughput

0.437

High

227228

EZH2
Histone-lysine N-methyltransferase EZH2

1

7

High-throughput

0.437

High

227253

ESR2
Estrogen receptor beta

1

12

High-throughput

0.407

High

227222

ODFP1
Outer dense fiber protein 1

2

0

High-throughput

0.316

High

227223

RTP5
Receptor-transporting protein 5

2

0

High-throughput

0.316

High

227260

3BHS7
3 beta-hydroxysteroid dehydrogenase type 7

2

0

High-throughput

0.316

High

227248

SCPDL
Saccharopine dehydrogenase-like oxidoreductase

1

0

High-throughput

0.279

Low

227255

ERGI1
Endoplasmic reticulum-Golgi intermediate compartment protein 1

1

0

High-throughput

0.279

Low

227231

MGT5B
Alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase B

1

0

High-throughput

0.251

Low


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Last updated: 11Aug2025