HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: WDR18 (Q9BV38)
WD repeat-containing protein 18
Gene: WDR18

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 432
+	Hs
		903207 CUL3_HUMAN (1-768): 0: 951: 100.00		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		1042101 CUL3_HUMAN (1-768): 0: 951: 100.00		POC1B_HUMAN (203-410): 5.86e-38: 145: 10.95
+	Hs
		1042655 CUL3_HUMAN (1-768): 0: 951: 100.00		NLE1_HUMAN (1-106): 3.14e-28: 117: 19.63
+	Hs
		1017378 CUL3_HUMAN (1-768): 0: 951: 100.00		CDC20_HUMAN (31-153): 3.74e-13: 72.9: 15.52
+	Hs
		1041647 CUL3_HUMAN (1-768): 0: 951: 100.00		TAF5_HUMAN (9-141): 3.19e-12: 70.5: 15.19
+	Hs
		1043499 CUL4B_HUMAN (5-768): 0: 779: 36.77		FBXW7_HUMAN (66-406): 4.11e-66: 225: 18.26
+	Hs
		1043157 CUL4A_HUMAN (10-768): 0: 791: 38.32		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Hs
		903208 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		1043509 CUL4B_HUMAN (5-768): 0: 779: 36.77		SNR40_HUMAN (113-413): 1.61e-57: 194: 14.80
+	Hs
		903209 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5_HUMAN (152-432): 8.2e-55: 186: 14.75
+	Hs
		1043085 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5B_HUMAN (208-432): 9.97e-43: 154: 13.66
+	Hs
		1043114 CUL4A_HUMAN (10-768): 0: 791: 38.32		POC1B_HUMAN (203-410): 5.86e-38: 145: 10.95
+	Hs
		1043441 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5B_HUMAN (208-432): 9.97e-43: 154: 13.66
+	Hs
		560878 CUL4A_HUMAN (10-768): 0: 791: 38.32		GBB3_HUMAN (115-339): 3.33e-35: 135: 16.52
+	Hs
		1043469 CUL4B_HUMAN (5-768): 0: 779: 36.77		POC1B_HUMAN (203-410): 5.86e-38: 145: 10.95
+	Hs
		792982 CUL4A_HUMAN (10-768): 0: 791: 38.32		LIS1_HUMAN (247-430): 5.11e-28: 116: 14.29
+	Hs
		245601 CUL4B_HUMAN (5-768): 0: 779: 36.77		TBL1X_HUMAN (3-110): 1.72e-27: 116: 13.76
+	Hs
		1043562 CUL4B_HUMAN (5-768): 0: 779: 36.77		TBL1R_HUMAN (5-110): 6.4e-27: 114: 14.02
+	Hs
		1043340 CUL4A_HUMAN (10-768): 0: 791: 38.32		WSB1_HUMAN (84-310): 5.68e-21: 96.4: 19.92
+	Hs
		154680 CUL4A_HUMAN (10-768): 0: 791: 38.32		GNB5_HUMAN (60-296): 3.93e-09: 60.1: 27.09