HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: MK67I (Q9BYG3)
MKI67 FHA domain-interacting nucleolar phosphoprotein (Nucleolar phosphoprotein Nopp34) (Nucleolar protein interacting with the FHA domain of pKI-67) (hNIFK)
Gene: NIFK

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 293
+	Hs
		963517 CUL3_HUMAN (1-768): 0: 951: 100.00		TIAR_HUMAN (39-289): 7.08e-48: 165: 13.44
+	Hs
		680448 CUL3_HUMAN (1-768): 0: 951: 100.00		TIA1_HUMAN (40-289): 7.87e-47: 163: 12.89
+	Hs
		1031317 CUL3_HUMAN (1-768): 0: 951: 100.00		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516505 CUL3_HUMAN (1-768): 0: 951: 100.00		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		1042781 CUL3_HUMAN (1-768): 0: 951: 100.00		PUF60_HUMAN (31-234): 4.14e-30: 120: 17.96
+	Hs
		1020253 CUL3_HUMAN (1-768): 0: 951: 100.00		ELAV2_HUMAN (38-128): 7.23e-24: 101: 26.37
+	Hs
		1041638 CUL3_HUMAN (1-768): 0: 951: 100.00		SF3B4_HUMAN (26-283): 2.83e-17: 83.3: 11.92
+	Hs
		963518 CUL4A_HUMAN (10-768): 0: 791: 38.32		TIAR_HUMAN (39-289): 7.08e-48: 165: 13.44
+	Hs
		680449 CUL4A_HUMAN (10-768): 0: 791: 38.32		TIA1_HUMAN (40-289): 7.87e-47: 163: 12.89
+	Hs
		963519 CUL4B_HUMAN (5-768): 0: 779: 36.77		TIAR_HUMAN (39-289): 7.08e-48: 165: 13.44
+	Hs
		1031318 CUL4A_HUMAN (10-768): 0: 791: 38.32		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516506 CUL4A_HUMAN (10-768): 0: 791: 38.32		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		1031319 CUL4B_HUMAN (5-768): 0: 779: 36.77		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516507 CUL4B_HUMAN (5-768): 0: 779: 36.77		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14
+	Hs
		1043573 CUL4B_HUMAN (5-768): 0: 779: 36.77		CSTFT_HUMAN (46-229): 2.35e-38: 144: 19.60
+	Hs
		703382 CUL4B_HUMAN (5-768): 0: 779: 36.77		CSTF2_HUMAN (46-218): 6.49e-36: 137: 18.62
+	Hs
		963515 CUL1_HUMAN (18-768): 0: 707: 30.57		TIAR_HUMAN (39-289): 7.08e-48: 165: 13.44
+	Hs
		680446 CUL1_HUMAN (18-768): 0: 707: 30.57		TIA1_HUMAN (40-289): 7.87e-47: 163: 12.89
+	Hs
		1031315 CUL1_HUMAN (18-768): 0: 707: 30.57		PABP4_HUMAN (35-225): 7.16e-41: 151: 14.66
+	Hs
		516503 CUL1_HUMAN (18-768): 0: 707: 30.57		PABP1_HUMAN (35-225): 1.96e-40: 150: 14.14