Protein: MK01
Mitogen-activated protein kinase 1 (MAP kinase 1) (MAPK 1) (EC 2.7.11.24) (ERT1) (Extracellular signal-regulated kinase 2) (ERK-2) (MAP kinase isoform p42) (p42-MAPK) (Mitogen-activated protein kinase 2) (MAP kinase 2) (MAPK 2)

Gene: MK01, MAPK1
Organism: Homo sapiens
Interactions: 437
UniProt ID: P28482

Gene Ontology (top 5):
GO:0000165 - MAPK cascade
GO:0001784 - phosphotyrosine residue binding
GO:0003677 - DNA binding
GO:0004674 - protein serine/threonine kinase activity
GO:0004707 - MAP kinase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

703543

MP2K1
Dual specificity mitogen-activated protein kinase kinase 1

15

20

Small-scale

0.983

High

703603

KS6A1
Ribosomal protein S6 kinase alpha-1

14

20

Small-scale

0.981

High

703602

KS6A2
Ribosomal protein S6 kinase alpha-2

11

20

Small-scale

0.979

High

703506

KS6A3
Ribosomal protein S6 kinase alpha-3

13

20

Small-scale

0.979

High

703610

DUS6
Dual specificity protein phosphatase 6

12

20

Small-scale

0.975

High

703695

MKNK1
MAP kinase-interacting serine/threonine-protein kinase 1

8

20

Small-scale

0.969

High

703565

DUS4
Dual specificity protein phosphatase 4

9

20

Small-scale

0.966

High

703599

PEA15
Astrocytic phosphoprotein PEA-15

7

4

Small-scale

0.966

High

691636

MK03
Mitogen-activated protein kinase 3

8

19

Small-scale

0.966

High

703689

DUS9
Dual specificity protein phosphatase 9

8

20

Small-scale

0.964

High

400330

RAF1
RAF proto-oncogene serine/threonine-protein kinase

6

20

Small-scale

0.951

High

703444

DUS1
Dual specificity protein phosphatase 1

6

20

Small-scale

0.946

High

703606

MK14
Mitogen-activated protein kinase 14

6

17

Small-scale

0.936

High

703717

MKNK2
MAP kinase-interacting serine/threonine-protein kinase 2

5

20

Small-scale

0.931

High

58703

PTPC1
Protein tyrosine phosphatase domain-containing protein 1

5

20

High-throughput

0.926

High

703495

DHYS
Deoxyhypusine synthase

5

3

High-throughput

0.908

High

703443

MK01
Mitogen-activated protein kinase 1

5

17

Small-scale

0.906

High

703571

M3K1
Mitogen-activated protein kinase kinase kinase 1

4

20

Small-scale

0.893

High

290297

KS6A4
Ribosomal protein S6 kinase alpha-4

4

20

Small-scale

0.893

High

703464

MP2K2
Dual specificity mitogen-activated protein kinase kinase 2

4

20

Small-scale

0.891

High

703549

DUSP2
Dual specificity protein phosphatase 2

4

20

Small-scale

0.881

High

703494

MAPK2
MAP kinase-activated protein kinase 2

4

20

Small-scale

0.878

High

703578

SQSTM
Sequestosome-1

3

6

Small-scale

0.839

High

703611

DUS7
Dual specificity protein phosphatase 7

3

20

Small-scale

0.839

High

161953

MP2K7
Dual specificity mitogen-activated protein kinase kinase 7

3

20

Small-scale

0.825

High

439962

LCK
Tyrosine-protein kinase Lck

2

4

Small-scale

0.812

High

703451

MPIP3
M-phase inducer phosphatase 3

2

5

Small-scale

0.806

High

703504

DUS3
Dual specificity protein phosphatase 3

2

20

Small-scale

0.799

High

167230

KLF11
Krueppel-like factor 11

2

6

Small-scale

0.789

High

703740

KS6A6
Ribosomal protein S6 kinase alpha-6

2

20

High-throughput

0.789

High

74329

ZBT42
Zinc finger and BTB domain-containing protein 42

2

3

High-throughput

0.783

High

302388

RNF8
E3 ubiquitin-protein ligase RNF8

2

3

High-throughput

0.783

High

586973

CHIN
N-chimaerin

2

1

High-throughput

0.783

High

464828

SP1
Transcription factor Sp1

2

6

Small-scale

0.778

High

578390

BRAF
Serine/threonine-protein kinase B-raf

2

20

Small-scale

0.778

High

703749

GAB2
GRB2-associated-binding protein 2

2

6

Small-scale

0.778

High

584481

VAV
Proto-oncogene vav

2

3

Small-scale

0.776

High

703698

DUS16
Dual specificity protein phosphatase 16

2

20

Small-scale

0.776

High

703511

DAPK1
Death-associated protein kinase 1

1

14

Small-scale

0.774

High

703692

RHG09
Rho GTPase-activating protein 9

1

6

Small-scale

0.770

High

622411

ELK1
ETS domain-containing protein Elk-1

19

19

Small-scale

0.766

High

388045

MBP
Myelin basic protein

16

7

Small-scale

0.763

High

703601

PTPRR
Receptor-type tyrosine-protein phosphatase R

10

20

Small-scale

0.758

High

240828

PRKN
E3 ubiquitin-protein ligase parkin

2

8

Small-scale

0.754

High

703735

UBQL2
Ubiquilin-2

2

3

Small-scale

0.754

High

703746

DUS12
Dual specificity protein phosphatase 12

2

20

High-throughput

0.754

High

703748

CILK1
Serine/threonine-protein kinase ICK

2

13

Small-scale

0.754

High

703458

PTN7
Tyrosine-protein phosphatase non-receptor type 7

7

20

Small-scale

0.754

High

471728

PTPRC
Receptor-type tyrosine-protein phosphatase C

1

11

Small-scale

0.747

High

703501

GSK3B
Glycogen synthase kinase-3 beta

1

17

Small-scale

0.747

High

703531

CSK21
Casein kinase II subunit alpha

1

20

Small-scale

0.747

High

703528

RPB7
DNA-directed RNA polymerase II subunit RPB7

2

0

High-throughput

0.742

High

703747

PLAL2
Zinc finger protein PLAGL2

2

0

High-throughput

0.742

High

703507

NEK2
Serine/threonine-protein kinase Nek2

1

12

Small-scale

0.740

High

177176

ANR28
Serine/threonine-protein phosphatase 6 regulatory ankyrin repeat subunit A

2

2

High-throughput

0.737

High

703485

MP2K3
Dual specificity mitogen-activated protein kinase kinase 3

2

20

High-throughput

0.737

High

703568

MK07
Mitogen-activated protein kinase 7

2

18

High-throughput

0.737

High

703575

ILK
Scaffold protein ILK

2

20

High-throughput

0.737

High

703685

AGAP3
Arf-GAP with GTPase, ANK repeat and PH domain-containing protein 3

2

5

High-throughput

0.737

High

703462

PPM1A
Protein phosphatase 1A

1

12

Small-scale

0.734

High

429358

JUN
Transcription factor Jun

6

18

Small-scale

0.726

High

703455

C2TA
MHC class II transactivator

1

3

Small-scale

0.724

High

703718

LRRC4
Leucine-rich repeat-containing protein 4

1

1

Small-scale

0.724

High

703513

PTN5
Tyrosine-protein phosphatase non-receptor type 5

5

20

Small-scale

0.720

High

612882

EGR1
Early growth response protein 1

2

0

Small-scale

0.716

High

703483

NOTC1
Neurogenic locus notch homolog protein 1

1

1

High-throughput

0.715

High

703661

STYX
Serine/threonine/tyrosine-interacting protein

1

20

Small-scale

0.713

High

703544

M3K10
Mitogen-activated protein kinase kinase kinase 10

1

18

Small-scale

0.710

High

703636

NOXA1
NADPH oxidase activator 1

1

1

Small-scale

0.710

High

703754

DYR1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B

1

17

Small-scale

0.710

High

413248

P53
Cellular tumor antigen p53

5

4

Small-scale

0.710

High

583463

ATF2
Cyclic AMP-dependent transcription factor ATF-2

5

17

Small-scale

0.707

High

371241

MYC
Myc proto-oncogene protein

4

7

Small-scale

0.698

High

703521

MTPN
Myotrophin

1

8

High-throughput

0.698

High

539864

RALB
Ras-related protein Ral-B

1

4

High-throughput

0.691

High

549059

CDK4
Cyclin-dependent kinase 4

1

17

High-throughput

0.691

High

625203

CSK22
Casein kinase II subunit alpha'

1

19

High-throughput

0.691

High

703479

DCC
Netrin receptor DCC

1

3

Small-scale

0.691

High

703512

MK12
Mitogen-activated protein kinase 12

1

18

High-throughput

0.691

High

703643

ZN444
Zinc finger protein 444

1

2

High-throughput

0.691

High

395544

ESR1
Estrogen receptor

4

14

Small-scale

0.683

High

276275

HMMR
Hyaluronan mediated motility receptor

4

4

Small-scale

0.683

High

703691

LZTS2
Leucine zipper putative tumor suppressor 2

4

3

High-throughput

0.681

High

703502

ERF
ETS domain-containing transcription factor ERF

4

19

High-throughput

0.678

High

703562

PTPRJ
Receptor-type tyrosine-protein phosphatase eta

1

14

Small-scale

0.667

High

439652

INSR
Insulin receptor

1

7

Small-scale

0.665

High

703452

AGTR1
Type-1 angiotensin II receptor

1

2

Small-scale

0.665

High

703471

CCNF
Cyclin-F

1

2

High-throughput

0.665

High

703539

KPCE
Protein kinase C epsilon type

1

8

Small-scale

0.665

High

703589

CASP8
Caspase-8

1

5

Small-scale

0.665

High

703454

ARRB2
Beta-arrestin-2

3

5

Small-scale

0.662

High

703604

SMAD1
Mothers against decapentaplegic homolog 1

3

3

Small-scale

0.655

High

703608

HIF1A
Hypoxia-inducible factor 1-alpha

3

3

Small-scale

0.655

High

703593

TNIP1
TNFAIP3-interacting protein 1

3

0

Small-scale

0.654

High

703609

DUS5
Dual specificity protein phosphatase 5

1

20

Small-scale

0.653

High

703639

GCC2
GRIP and coiled-coil domain-containing protein 2

3

5

High-throughput

0.650

High

703756

IPP
Actin-binding protein IPP

3

1

High-throughput

0.650

High

634908

BCL3
B-cell lymphoma 3 protein

1

7

Small-scale

0.647

High

703463

VGFR2
Vascular endothelial growth factor receptor 2

1

9

Small-scale

0.647

High

703482

MP2K4
Dual specificity mitogen-activated protein kinase kinase 4

1

20

Small-scale

0.647

High

703509

MP2K6
Dual specificity mitogen-activated protein kinase kinase 6

1

20

Small-scale

0.647

High

703537

TIAR
Nucleolysin TIAR

1

7

Small-scale

0.647

High

703583

SCRIB
Protein scribble homolog

1

12

Small-scale

0.647

High

703667

TITIN
Titin

1

3

Small-scale

0.647

High

703703

TNKS2
Poly [ADP-ribose] polymerase tankyrase-2

1

2

Small-scale

0.647

High

703546

TF65
Transcription factor p65

3

2

Small-scale

0.646

High

703484

IEX1
Radiation-inducible immediate-early gene IEX-1

2

1

Small-scale

0.643

High

703446

SHC1
SHC-transforming protein 1

2

4

Small-scale

0.641

High

703558

SRBP2
Sterol regulatory element-binding protein 2

2

8

Small-scale

0.639

High

341526

EYA4
Protein phosphatase EYA4

2

2

Small-scale

0.634

High

703515

TERA
Transitional endoplasmic reticulum ATPase

3

3

High-throughput

0.633

High

622527

TNR1A
Tumor necrosis factor receptor superfamily member 1A

2

3

Small-scale

0.629

High

703556

EP300
Histone acetyltransferase p300

2

10

Small-scale

0.629

High

703729

HDAC6
Protein deacetylase HDAC6

2

6

Small-scale

0.629

High

703475

STA5A
Signal transducer and activator of transcription 5A

2

5

Small-scale

0.624

High

703665

SYNE2
Nesprin-2

2

6

Small-scale

0.624

High

703699

SHAN3
SH3 and multiple ankyrin repeat domains protein 3

1

8

High-throughput

0.621

High

703644

RPTOR
Regulatory-associated protein of mTOR

2

4

Small-scale

0.619

High

520516

RARA
Retinoic acid receptor alpha

2

12

Small-scale

0.619

High

703638

ZC3C1
Zinc finger C3HC-type protein 1

2

1

Small-scale

0.619

High

171838

ZN263
Zinc finger protein 263

1

2

Small-scale

0.618

High

349816

SNAI1
Zinc finger protein SNAI1

1

1

Small-scale

0.618

High

375206

RASK
GTPase KRas

1

2

Small-scale

0.618

High

411413

NTRK1
High affinity nerve growth factor receptor

1

9

High-throughput

0.618

High

557118

SRC
Proto-oncogene tyrosine-protein kinase Src

1

4

Small-scale

0.618

High

599157

IL7RA
Interleukin-7 receptor subunit alpha

1

1

High-throughput

0.618

High

655077

SFPQ
Splicing factor, proline- and glutamine-rich

1

6

Small-scale

0.618

High

664643

CCND1
G1/S-specific cyclin-D1

1

1

Small-scale

0.618

High

703450

MPIP1
M-phase inducer phosphatase 1

1

5

High-throughput

0.618

High

703456

RYK
Tyrosine-protein kinase RYK

1

9

Small-scale

0.618

High

703477

CDN2B
Cyclin-dependent kinase 4 inhibitor B

1

11

High-throughput

0.618

High

703478

CDN2C
Cyclin-dependent kinase 4 inhibitor C

1

10

High-throughput

0.618

High

703508

RND2
Rho-related GTP-binding protein RhoN

1

2

Small-scale

0.618

High

703517

CDN2D
Cyclin-dependent kinase 4 inhibitor D

1

11

High-throughput

0.618

High

703523

ABCE1
ATP-binding cassette sub-family E member 1

1

1

High-throughput

0.618

High

703563

TRAP1
Heat shock protein 75 kDa, mitochondrial

1

10

Small-scale

0.618

High

703569

DUS8
Dual specificity protein phosphatase 8

1

20

High-throughput

0.618

High

703572

PD2R
Prostaglandin D2 receptor

1

4

Small-scale

0.618

High

703598

PDCD1
Programmed cell death protein 1

1

1

Small-scale

0.618

High

703616

LRRK2
Leucine-rich repeat serine/threonine-protein kinase 2

1

16

High-throughput

0.618

High

703620

TENS2
Tensin-2

1

3

High-throughput

0.618

High

703622

SCMC2
Mitochondrial adenyl nucleotide antiporter SLC25A25

1

13

High-throughput

0.618

High

703626

KSR2
Kinase suppressor of Ras 2

1

15

Small-scale

0.618

High

703629

TRI67
Tripartite motif-containing protein 67

1

10

High-throughput

0.618

High

703659

DUS19
Dual specificity protein phosphatase 19

1

20

High-throughput

0.618

High

703686

BARD1
BRCA1-associated RING domain protein 1

1

5

High-throughput

0.618

High

703696

SCMC3
Mitochondrial adenyl nucleotide antiporter SLC25A23

1

13

High-throughput

0.618

High

703708

PKHA4
Pleckstrin homology domain-containing family A member 4

1

4

High-throughput

0.618

High

703737

DS13B
Dual specificity protein phosphatase 13B

1

20

High-throughput

0.618

High

703741

TNIK
TRAF2 and NCK-interacting protein kinase

1

20

High-throughput

0.618

High

703745

ALK
ALK tyrosine kinase receptor

1

12

Small-scale

0.618

High

703759

DUS10
Dual specificity protein phosphatase 10

1

20

High-throughput

0.618

High

703566

REST
RE1-silencing transcription factor

1

0

Small-scale

0.614

High

703468

SYUA
Alpha-synuclein

2

3

Small-scale

0.611

High

703535

SMAD3
Mothers against decapentaplegic homolog 3

2

3

Small-scale

0.611

High

279286

TULP3
Tubby-related protein 3

2

4

High-throughput

0.611

High

703461

MSX2
Homeobox protein MSX-2

2

3

High-throughput

0.606

High

703552

TLE5
TLE family member 5

2

1

High-throughput

0.606

High

703623

PPR18
Phostensin

2

2

High-throughput

0.606

High

522047

BCL2
Apoptosis regulator Bcl-2

1

2

Small-scale

0.604

High

552756

TPR
Nucleoprotein TPR

2

4

Small-scale

0.602

High

703673

CBP
CREB-binding protein

2

7

Small-scale

0.602

High

703758

NCOA3
Nuclear receptor coactivator 3

2

4

Small-scale

0.602

High

703470

STAT3
Signal transducer and activator of transcription 3

2

5

Small-scale

0.601

High

703670

PHF3
PHD finger protein 3

2

7

High-throughput

0.601

High

703632

CSN6
COP9 signalosome complex subunit 6

1

1

Small-scale

0.597

High

703487

PA24A
Cytosolic phospholipase A2

2

4

Small-scale

0.595

High

703660

FRS2
Fibroblast growth factor receptor substrate 2

2

4

Small-scale

0.594

High

703533

ADA17
Disintegrin and metalloproteinase domain-containing protein 17

1

5

Small-scale

0.589

High

703519

HDAC4
Histone deacetylase 4

1

6

Small-scale

0.586

High

703536

HSF1
Heat shock factor protein 1

1

8

Small-scale

0.586

High

703503

TOB1
Protein Tob1

1

2

Small-scale

0.586

High

529149

TAU
Microtubule-associated protein tau

2

13

Small-scale

0.585

High

703447

PML
Protein PML

2

7

Small-scale

0.584

High

703467

PPARG
Peroxisome proliferator-activated receptor gamma

2

13

Small-scale

0.584

High

680783

PSA1
Proteasome subunit alpha type-1

2

0

High-throughput

0.580

High

703524

STXB1
Syntaxin-binding protein 1

2

0

High-throughput

0.580

High

703687

MDFI
MyoD family inhibitor

2

0

High-throughput

0.580

High

572999

KPYM
Pyruvate kinase PKM

1

4

Small-scale

0.578

High

703500

TSC2
Tuberin

1

4

Small-scale

0.578

High

703716

CYBP
Calcyclin-binding protein

2

0

Small-scale

0.577

High

463356

LYN
Tyrosine-protein kinase Lyn

1

4

Small-scale

0.575

High

471995

MET
Hepatocyte growth factor receptor

1

6

High-throughput

0.575

High

563252

CFTR
Cystic fibrosis transmembrane conductance regulator

1

1

High-throughput

0.575

High

619526

VCAM1
Vascular cell adhesion protein 1

1

4

High-throughput

0.575

High

658808

PTPRB
Receptor-type tyrosine-protein phosphatase beta

1

12

Small-scale

0.575

High

669160

ADA1D
Alpha-1D adrenergic receptor

1

2

Small-scale

0.575

High

703567

FADD
FAS-associated death domain protein

1

3

High-throughput

0.575

High

703621

PKHA7
Pleckstrin homology domain-containing family A member 7

1

5

High-throughput

0.575

High

703688

M3K3
Mitogen-activated protein kinase kinase kinase 3

1

18

Small-scale

0.575

High

703585

FHL2
Four and a half LIM domains protein 2

1

8

Small-scale

0.573

High

135509

DNM1L
Dynamin-1-like protein

2

1

Small-scale

0.571

High

174941

SC16A
Protein transport protein Sec16A

2

3

High-throughput

0.571

High

521552

H14
Histone H1.4

2

2

High-throughput

0.571

High

595692

H13
Histone H1.3

2

2

High-throughput

0.571

High

655710

TBG1
Tubulin gamma-1 chain

2

15

High-throughput

0.571

High

703460

RL22
Large ribosomal subunit protein eL22

2

1

High-throughput

0.571

High

703472

ETV3
ETS translocation variant 3

2

19

High-throughput

0.571

High

703488

RPGP1
Rap1 GTPase-activating protein 1

2

4

High-throughput

0.571

High

703586

TRI25
E3 ubiquitin/ISG15 ligase TRIM25

2

4

High-throughput

0.571

High

703614

NKAPL
NKAP-like protein

2

1

High-throughput

0.571

High

703624

MZT2B
Mitotic-spindle organizing protein 2B

2

1

High-throughput

0.571

High

703645

NKAP
NF-kappa-B-activating protein

2

1

High-throughput

0.571

High

703656

COP1
E3 ubiquitin-protein ligase COP1

2

4

High-throughput

0.571

High

703671

HMHA1
Rho GTPase-activating protein 45 [Cleaved into: Minor histocompatibility antigen HA-1

2

3

High-throughput

0.571

High

703677

MRTFA
Myocardin-related transcription factor A

2

7

High-throughput

0.571

High

703679

GCP3
Gamma-tubulin complex component 3

2

6

High-throughput

0.571

High

703680

ARHGQ
Rho guanine nucleotide exchange factor 26

2

4

High-throughput

0.571

High

703694

GCP2
Gamma-tubulin complex component 2

2

6

High-throughput

0.571

High

703722

TBG2
Tubulin gamma-2 chain

2

13

High-throughput

0.571

High

703732

GCP4
Gamma-tubulin complex component 4

2

6

High-throughput

0.571

High

703739

DDX41
Probable ATP-dependent RNA helicase DDX41

2

3

High-throughput

0.571

High

703743

MRTFB
Myocardin-related transcription factor B

2

4

High-throughput

0.571

High

219694

FOXO3
Forkhead box protein O3

1

4

Small-scale

0.561

High

250212

VINEX
Vinexin

1

1

Small-scale

0.561

High

254060

CTND1
Catenin delta-1

1

3

Small-scale

0.561

High

325694

UBR5
E3 ubiquitin-protein ligase UBR5

1

4

Small-scale

0.561

High

603846

CXA1
Gap junction alpha-1 protein

1

2

Small-scale

0.561

High

615313

ITB6
Integrin beta-6

1

3

Small-scale

0.561

High

703480

NR4A2
Nuclear receptor subfamily 4 group A member 2

1

11

Small-scale

0.561

High

703550

C1QBP
Complement component 1 Q subcomponent-binding protein, mitochondrial

1

1

Small-scale

0.561

High

703561

ILF3
Interleukin enhancer-binding factor 3

1

2

Small-scale

0.561

High

703595

HERC3
Probable E3 ubiquitin-protein ligase HERC3

1

2

Small-scale

0.561

High

703596

SYK
Lysine--tRNA ligase

1

2

Small-scale

0.561

High

703635

MTA70
N(6)-adenosine-methyltransferase catalytic subunit METTL3

1

2

Small-scale

0.561

High

703486

IQGA1
Ras GTPase-activating-like protein IQGAP1

1

8

Small-scale

0.554

High

703751

FBW1A
F-box/WD repeat-containing protein 1A

1

8

Small-scale

0.552

High

420380

AT1A1
Sodium/potassium-transporting ATPase subunit alpha-1

1

5

Small-scale

0.550

High

437100

K2C8
Keratin, type II cytoskeletal 8

1

2

Small-scale

0.550

High

599700

YBOX3
Y-box-binding protein 3

1

2

Small-scale

0.550

High

605967

CAN2
Calpain-2 catalytic subunit

1

2

Small-scale

0.550

High

703466

SRBP1
Sterol regulatory element-binding protein 1

1

8

Small-scale

0.550

High

703516

CASP9
Caspase-9

1

5

Small-scale

0.550

High

703530

YBOX1
Y-box-binding protein 1

1

2

Small-scale

0.550

High

703574

2A5G
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform

1

1

Small-scale

0.550

High

703714

GORS2
Golgi reassembly-stacking protein 2

1

5

Small-scale

0.550

High

703555

MZT1
Mitotic-spindle organizing protein 1

2

0

High-throughput

0.547

High

703669

H1X
Histone H1.10

2

0

High-throughput

0.547

High

703681

OTUB1
Ubiquitin thioesterase OTUB1

2

0

High-throughput

0.547

High

703711

EGLN3
Prolyl hydroxylase EGLN3

1

1

High-throughput

0.541

High

703492

MAOX
NADP-dependent malic enzyme

1

0

Small-scale

0.537

High

703540

CENPE
Centromere-associated protein E

1

0

Small-scale

0.537

High

542346

TOP2A
DNA topoisomerase 2-alpha

1

2

Small-scale

0.536

High

243893

JIP4
C-Jun-amino-terminal kinase-interacting protein 4

1

5

High-throughput

0.536

High

249722

DOK2
Docking protein 2

1

7

High-throughput

0.536

High

290461

SURF6
Surfeit locus protein 6

1

1

High-throughput

0.536

High

481111

HMGB1
High mobility group protein B1

1

7

High-throughput

0.536

High

703445

GRN
Progranulin

1

2

High-throughput

0.536

High

703489

CAPZB
F-actin-capping protein subunit beta

1

1

High-throughput

0.536

High

703491

NPTX2
Neuronal pentraxin-2

1

3

High-throughput

0.536

High

703570

GPS2
G protein pathway suppressor 2

1

1

High-throughput

0.536

High

703584

MPP2
MAGUK p55 subfamily member 2

1

8

High-throughput

0.536

High

703607

ECM1
Extracellular matrix protein 1

1

1

High-throughput

0.536

High

703619

CE350
Centrosome-associated protein 350

1

2

High-throughput

0.536

High

703627

PPR21
Protein phosphatase 1 regulatory subunit 21

1

1

High-throughput

0.536

High

703630

FBX50
F-box only protein 50

1

1

High-throughput

0.536

High

703633

RAI1
Retinoic acid-induced protein 1

1

3

High-throughput

0.536

High

703640

HSC20
Iron-sulfur cluster co-chaperone protein HscB

1

1

High-throughput

0.536

High

703649

UXS1
UDP-glucuronic acid decarboxylase 1

1

2

High-throughput

0.536

High

703654

NAV1
Neuron navigator 1

1

4

High-throughput

0.536

High

703662

PDC6I
Programmed cell death 6-interacting protein

1

7

High-throughput

0.536

High

703663

SNR27
U4/U6.U5 small nuclear ribonucleoprotein 27 kDa protein

1

1

High-throughput

0.536

High

703668

RFFL
E3 ubiquitin-protein ligase rififylin

1

3

High-throughput

0.536

High

703707

FA83D
Protein FAM83D

1

1

High-throughput

0.536

High

703712

PAAT
ATPase PAAT

1

1

High-throughput

0.536

High

703720

E41L5
Band 4.1-like protein 5

1

5

High-throughput

0.536

High

703727

CLIC5
Chloride intracellular channel protein 5

1

1

High-throughput

0.536

High

703733

TCF20
Transcription factor 20

1

6

High-throughput

0.536

High

703736

TRPS1
Zinc finger transcription factor Trps1

1

4

High-throughput

0.536

High

105397

APRIO
Alternative prion protein

2

1

High-throughput

0.533

High

703750

TPPC4
Trafficking protein particle complex subunit 4

1

2

Small-scale

0.529

High

703744

HSF4
Heat shock factor protein 4

1

8

Small-scale

0.528

High

703734

LTOR3
Ragulator complex protein LAMTOR3

1

2

Small-scale

0.527

High

703658

BRX1
Ribosome biogenesis protein BRX1 homolog

2

1

High-throughput

0.521

High

703612

GNPTA
N-acetylglucosamine-1-phosphotransferase subunits alpha/beta

1

0

High-throughput

0.518

High

703702

IF3M
Translation initiation factor IF-3, mitochondrial

1

0

High-throughput

0.518

High

486988

PARP1
Poly [ADP-ribose] polymerase 1

1

4

Small-scale

0.516

High

302693

SYUG
Gamma-synuclein

1

3

Small-scale

0.515

High

703576

ADA15
Disintegrin and metalloproteinase domain-containing protein 15

1

5

Small-scale

0.515

High

703664

STAB2
Stabilin-2

1

3

Small-scale

0.515

High

421549

A4
Amyloid-beta precursor protein

1

2

High-throughput

0.515

High

320312

PHF14
PHD finger protein 14

1

0

High-throughput

0.513

High

423742

APOD
Apolipoprotein D

1

0

High-throughput

0.513

High

408686

G3P
Glyceraldehyde-3-phosphate dehydrogenase

1

4

High-throughput

0.508

High

703541

ID2
DNA-binding protein inhibitor ID-2

1

1

High-throughput

0.508

High

450298

TY3H
Tyrosine 3-monooxygenase

1

2

Small-scale

0.501

High

519770

ANDR
Androgen receptor

1

14

Small-scale

0.501

High

543464

VDR
Vitamin D3 receptor

1

9

Small-scale

0.501

High

604607

UBF1
Nucleolar transcription factor 1

1

6

Small-scale

0.501

High

606276

CEBPB
CCAAT/enhancer-binding protein beta

1

13

Small-scale

0.501

High

625765

RXRA
Retinoic acid receptor RXR-alpha

1

13

Small-scale

0.501

High

702320

ELK4
ETS domain-containing protein Elk-4

1

18

Small-scale

0.501

High

703448

PRDX6
Peroxiredoxin-6

1

5

Small-scale

0.501

High

703453

FCG2B
Low affinity immunoglobulin gamma Fc region receptor II-b

1

6

Small-scale

0.501

High

703473

HNF4A
Hepatocyte nuclear factor 4-alpha

1

11

Small-scale

0.501

High

703481

GATA4
Transcription factor GATA-4

1

4

Small-scale

0.501

High

703496

ARRB1
Beta-arrestin-1

1

5

Small-scale

0.501

High

703499

NU153
Nuclear pore complex protein Nup153

1

11

Small-scale

0.501

High

703514

NRL
Neural retina-specific leucine zipper protein

1

4

Small-scale

0.501

High

703520

SOX10
Transcription factor SOX-10

1

9

Small-scale

0.501

High

703547

UBE3A
Ubiquitin-protein ligase E3A

1

3

Small-scale

0.501

High

703551

MCL1
Induced myeloid leukemia cell differentiation protein Mcl-1

1

2

Small-scale

0.501

High

703559

TFCP2
Alpha-globin transcription factor CP2

1

1

Small-scale

0.501

High

703573

ATM
Serine-protein kinase ATM

1

1

Small-scale

0.501

High

703579

4EBP1
Eukaryotic translation initiation factor 4E-binding protein 1

1

4

Small-scale

0.501

High

703600

2A5B
Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit beta isoform

1

1

Small-scale

0.501

High

703672

ESR2
Estrogen receptor beta

1

13

Small-scale

0.501

High

703675

TNR25
Tumor necrosis factor receptor superfamily member 25

1

3

Small-scale

0.501

High

703704

TXNIP
Thioredoxin-interacting protein

1

6

Small-scale

0.501

High

703706

CUED2
CUE domain-containing protein 2

1

1

Small-scale

0.501

High

703510

BIEA
Biliverdin reductase A

1

1

Small-scale

0.500

High

703615

SPXN4
Sperm protein associated with the nucleus on the X chromosome N4

1

3

High-throughput

0.489

High

703647

F133A
Protein FAM133A

1

1

High-throughput

0.489

High

703725

CUED1
CUE domain-containing protein 1

1

1

High-throughput

0.489

High

703730

CS025
UPF0449 protein C19orf25

1

1

High-throughput

0.489

High

456195

CATD
Cathepsin D

1

0

High-throughput

0.486

High

703534

IN35
Interferon-induced 35 kDa protein

1

0

High-throughput

0.486

High

388498

CRP

1

3

High-throughput

0.481

High

703587

KPRA
Phosphoribosyl pyrophosphate synthase-associated protein 1

1

5

High-throughput

0.481

High

703641

HOMEZ
Homeobox and leucine zipper protein Homez

1

1

High-throughput

0.481

High

703646

ENAH
Protein enabled homolog

1

4

High-throughput

0.481

High

703653

SP20H
Transcription factor SPT20 homolog

1

2

High-throughput

0.481

High

601570

HMGA1
High mobility group protein HMG-I/HMG-Y

1

0

Small-scale

0.480

High

703449

PEBP1
Phosphatidylethanolamine-binding protein 1

1

0

Small-scale

0.480

High

703538

RUNX1
Runt-related transcription factor 1

1

0

Small-scale

0.480

High

703542

PAX5
Paired box protein Pax-5

1

0

Small-scale

0.480

High

703553

PDE4D
3',5'-cyclic-AMP phosphodiesterase 4D

1

0

Small-scale

0.480

High

703648

BANP
Protein BANP

1

0

Small-scale

0.480

High

703690

CITE2
Cbp/p300-interacting transactivator 2

1

0

Small-scale

0.480

High

703724

RN216
E3 ubiquitin-protein ligase RNF216

1

0

Small-scale

0.480

High

703755

PKHM1
Pleckstrin homology domain-containing family M member 1

1

0

Small-scale

0.480

High

159521

DVL2
Segment polarity protein dishevelled homolog DVL-2

1

9

High-throughput

0.479

High

219603

B2L11
Bcl-2-like protein 11

1

1

Small-scale

0.479

High

227388

SPOP
Speckle-type POZ protein

1

4

Small-scale

0.479

High

259490

BRD4
Bromodomain-containing protein 4

1

6

High-throughput

0.479

High

269944

AUXI
Auxilin

1

2

High-throughput

0.479

High

315163

RECQ4
ATP-dependent DNA helicase Q4

1

5

High-throughput

0.479

High

324568

HEXI1
Protein HEXIM1

1

1

High-throughput

0.479

High

326925

UBE4B
Ubiquitin conjugation factor E4 B

1

4

Small-scale

0.479

High

334336

TRI16
Tripartite motif-containing protein 16

1

4

High-throughput

0.479

High

353792

PTTG1
Securin

1

1

Small-scale

0.479

High

370575

FOS
Protein c-Fos

1

16

Small-scale

0.479

High

379890

HLAB
HLA class I histocompatibility antigen, B alpha chain

1

2

High-throughput

0.479

High

442879

PRGR
Progesterone receptor

1

13

Small-scale

0.479

High

447986

ITAV
Integrin alpha-V

1

3

Small-scale

0.479

High

479770

GSTP1
Glutathione S-transferase P

1

1

Small-scale

0.479

High

587980

RFA2
Replication protein A 32 kDa subunit

1

3

High-throughput

0.479

High

593727

PECA1
Platelet endothelial cell adhesion molecule

1

8

Small-scale

0.479

High

605051

JUND
Transcription factor JunD

1

17

Small-scale

0.479

High

658954

PTPRE
Receptor-type tyrosine-protein phosphatase epsilon

1

11

Small-scale

0.479

High

694690

RFA1
Replication protein A 70 kDa DNA-binding subunit

1

3

High-throughput

0.479

High

703457

PHB1
Prohibitin 1

1

1

High-throughput

0.479

High

703459

RFA3
Replication protein A 14 kDa subunit

1

2

High-throughput

0.479

High

703465

PP1G
Serine/threonine-protein phosphatase PP1-gamma catalytic subunit

1

5

Small-scale

0.479

High

703469

BRCA1
Breast cancer type 1 susceptibility protein

1

4

Small-scale

0.479

High

703474

STAT1
Signal transducer and activator of transcription 1-alpha/beta

1

5

Small-scale

0.479

High

703476

CDN2A
Cyclin-dependent kinase inhibitor 2A

1

11

High-throughput

0.479

High

703493

PAXI
Paxillin

1

8

Small-scale

0.479

High

703498

MCM2
DNA replication licensing factor MCM2

1

7

High-throughput

0.479

High

703505

MECP2
Methyl-CpG-binding protein 2

1

2

High-throughput

0.479

High

703518

TPD52
Tumor protein D52

1

1

Small-scale

0.479

High

703522

PTEN
Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN

1

9

Small-scale

0.479

High

703525

WDR5
WD repeat-containing protein 5

1

4

High-throughput

0.479

High

703532

GTF2I
General transcription factor II-I

1

2

Small-scale

0.479

High

703545

CAV1
Caveolin-1

1

1

Small-scale

0.479

High

703548

PTN12
Tyrosine-protein phosphatase non-receptor type 12

1

15

High-throughput

0.479

High

703554

PPID
Peptidyl-prolyl cis-trans isomerase D

1

1

Small-scale

0.479

High

703560

TP53B
TP53-binding protein 1

1

4

High-throughput

0.479

High

703564

TP4A2
Protein tyrosine phosphatase type IVA 2

1

13

High-throughput

0.479

High

703577

SMAD4
Mothers against decapentaplegic homolog 4

1

3

Small-scale

0.479

High

703580

CUL1
Cullin-1

1

1

Small-scale

0.479

High

703581

FHL1
Four and a half LIM domains protein 1

1

7

Small-scale

0.479

High

703582

FHL3
Four and a half LIM domains protein 3

1

8

Small-scale

0.479

High

703588

UBP10
Ubiquitin carboxyl-terminal hydrolase 10

1

6

Small-scale

0.479

High

703590

CUL7
Cullin-7

1

2

High-throughput

0.479

High

703594

U5S1
116 kDa U5 small nuclear ribonucleoprotein component

1

5

High-throughput

0.479

High

703605

EZH2
Histone-lysine N-methyltransferase EZH2

1

1

High-throughput

0.479

High

703631

UBP34
Ubiquitin carboxyl-terminal hydrolase 34

1

3

High-throughput

0.479

High

703634

HUWE1
E3 ubiquitin-protein ligase HUWE1

1

1

High-throughput

0.479

High

703642

TRI22
E3 ubiquitin-protein ligase TRIM22

1

2

Small-scale

0.479

High

703651

SERB1
SERPINE1 mRNA-binding protein 1

1

2

High-throughput

0.479

High

703657

RIN3
Ras and Rab interactor 3

1

6

High-throughput

0.479

High

703674

ARHG2
Rho guanine nucleotide exchange factor 2

1

5

Small-scale

0.479

High

703676

TP4A1
Protein tyrosine phosphatase type IVA 1

1

20

High-throughput

0.479

High

703678

CLUA1
Clusterin-associated protein 1

1

1

High-throughput

0.479

High

703697

PRAX
Periaxin

1

9

High-throughput

0.479

High

703705

PTN23
Tyrosine-protein phosphatase non-receptor type 23

1

12

High-throughput

0.479

High

703709

ZCHC4
rRNA N(6)-adenosine-methyltransferase ZCCHC4

1

1

High-throughput

0.479

High

703713

ECT2
Protein ECT2

1

7

High-throughput

0.479

High

703715

CLSPN
Claspin

1

2

High-throughput

0.479

High

703719

EMAL4
Echinoderm microtubule-associated protein-like 4

1

1

High-throughput

0.479

High

703731

ZRAN1
Ubiquitin thioesterase ZRANB1

1

6

High-throughput

0.479

High

703738

RABX5
Rab5 GDP/GTP exchange factor

1

4

Small-scale

0.479

High

703742

PACN3
Protein kinase C and casein kinase substrate in neurons protein 3

1

1

High-throughput

0.479

High

703757

MAFB
Transcription factor MafB

1

11

High-throughput

0.479

High

46797

A0A384NQ31
Epididymis secretory sperm binding protein

1

4

High-throughput

0.470

High

703655

TNIP2
TNFAIP3-interacting protein 2

1

0

High-throughput

0.460

High

293251

CD123
Translation initiation factor eIF2 assembly protein

1

0

High-throughput

0.458

High

377415

INS
Insulin [Cleaved into: Insulin B chain; Insulin A chain]

1

0

High-throughput

0.458

High

665235

GA45A
Growth arrest and DNA damage-inducible protein GADD45 alpha

1

0

Small-scale

0.458

High

703527

UBE2H
Ubiquitin-conjugating enzyme E2 H

1

0

High-throughput

0.458

High

703591

HAPR1
HUWE1-associated protein modifying stress responses 1

1

0

High-throughput

0.458

High

703592

FL2D
Pre-mRNA-splicing regulator WTAP

1

0

Small-scale

0.458

High

703597

EEA1
Early endosome antigen 1

1

0

High-throughput

0.458

High

703618

MIC10
MICOS complex subunit MIC10

1

0

Small-scale

0.458

High

703625

LMBRL
Protein LMBR1L

1

0

High-throughput

0.458

High

703628

BAKOR
Beclin 1-associated autophagy-related key regulator

1

0

High-throughput

0.458

High

703650

RN149
E3 ubiquitin-protein ligase RNF149

1

0

High-throughput

0.458

High

703652

MTMRE
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR14

1

0

High-throughput

0.458

High

703666

DGCR8
Microprocessor complex subunit DGCR8

1

0

High-throughput

0.458

High

703683

CI072
Guanine nucleotide exchange factor C9orf72

1

0

High-throughput

0.458

High

703701

ATG5
Autophagy protein 5

1

0

High-throughput

0.458

High

703723

PHP14
14 kDa phosphohistidine phosphatase

1

0

High-throughput

0.458

High

703726

MTMR4
Phosphatidylinositol-3,5-bisphosphate 3-phosphatase MTMR4

1

0

High-throughput

0.458

High

703728

WWOX
WW domain-containing oxidoreductase

1

0

Small-scale

0.458

High

404686

PRIO
Major prion protein

1

1

High-throughput

0.445

High

409274

HLAA
HLA class I histocompatibility antigen, A alpha chain

1

2

High-throughput

0.445

High

577409

ETS1
Protein C-ets-1

1

19

Small-scale

0.445

High

703490

LEG7
Galectin-7

1

1

High-throughput

0.445

High

703526

PP1A
Serine/threonine-protein phosphatase PP1-alpha catalytic subunit

1

5

Small-scale

0.445

High

703529

PP2AA
Serine/threonine-protein phosphatase 2A catalytic subunit alpha isoform

1

7

Small-scale

0.445

High

703700

ZDHC5
Palmitoyltransferase ZDHHC5

1

1

High-throughput

0.445

High

703721

PDLI7
PDZ and LIM domain protein 7

1

5

High-throughput

0.445

High

703752

S27A5
Long-chain fatty acid transport protein 5

1

2

High-throughput

0.445

High

703617

HECD3
E3 ubiquitin-protein ligase HECTD3

1

4

Small-scale

0.437

High

703637

MGDP1
Magnesium-dependent phosphatase 1

1

1

High-throughput

0.437

High

703682

CD036
Uncharacterized protein C4orf36

1

1

High-throughput

0.437

High

703693

WDR83
WD repeat domain-containing protein 83

1

4

Small-scale

0.437

High

65701

SMHD1
Structural maintenance of chromosomes flexible hinge domain-containing protein 1

1

0

High-throughput

0.426

High

244928

KATIP
Katanin-interacting protein

1

0

High-throughput

0.426

High

703497

CEBPA
CCAAT/enhancer-binding protein alpha

1

11

High-throughput

0.408

High

703613

COBL1
Cordon-bleu protein-like 1

1

3

High-throughput

0.407

High

703684

MF14A
Hippocampus abundant transcript 1 protein

1

4

High-throughput

0.407

High

703710

WDCP
WD repeat and coiled-coil-containing protein

2

0

High-throughput

0.298

High

703557

SCRN3
Secernin-3

1

0

High-throughput

0.279

Low

703753

AAR2
Protein AAR2 homolog

1

0

High-throughput

0.249

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025