HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: NISCH (Q9Y2I1)
Nischarin (Imidazoline receptor 1) (I-1) (IR1) (Imidazoline receptor antisera-selected protein) (hIRAS) (Imidazoline-1 receptor) (I1R) (Imidazoline-1 receptor candidate protein) (I-1 receptor candidate protein) (I1R candidate protein)
Gene: NISCH

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	35563538, 21145461
Identification Methods	affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005654 - nucleoplasm GO:0005737 - cytoplasm GO:0005829 - cytosol GO:0005886 - plasma membrane GO:0016020 - membrane
Homologous interactions	5

Homologous interactions

Color coding for hit scores

	1 768 Hs			1 1504
+	Hs
		1042012 CUL3_HUMAN (1-768): 0: 951: 100.00		S11IP_HUMAN (129-540): 2.54e-55: 213: 23.61
+	Hs
		1041832 CUL3_HUMAN (1-768): 0: 951: 100.00		LRC8B_HUMAN (209-539): 4.52e-30: 131: 19.14
+	Hs
		1042425 CUL3_HUMAN (1-768): 0: 951: 100.00		LRRC1_HUMAN (202-471): 1.35e-19: 96.3: 21.22
+	Hs
		1041552 CUL3_HUMAN (1-768): 0: 951: 100.00		SCRIB_HUMAN (209-577): 1.3e-17: 91.7: 18.01
+	Hs
		1023157 CUL3_HUMAN (1-768): 0: 951: 100.00		FLII_HUMAN (198-387): 6.39e-13: 76.3: 17.81