HitPredict

Interactor 1: CUL3 (Q13618)
Cullin-3 (CUL-3)
Gene: CUL3

Interactor 2: WIPI4 (Q9Y484)
WD repeat domain phosphoinositide-interacting protein 4 (WIPI-4) (WD repeat-containing protein 45)
Gene: WDR45

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	35563538
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 768 Hs			1 360
+	Hs
		1042494 CUL3_HUMAN (1-768): 0: 951: 100.00		SKI8_HUMAN (117-274): 6.83e-36: 134: 20.89
+	Hs
		1042101 CUL3_HUMAN (1-768): 0: 951: 100.00		POC1B_HUMAN (3-175): 1.36e-28: 117: 7.48
+	Hs
		1043328 CUL4A_HUMAN (10-768): 0: 791: 38.32		WIPI2_HUMAN (7-357): 3.21e-89: 277: 20.77
+	Hs
		1041647 CUL3_HUMAN (1-768): 0: 951: 100.00		TAF5_HUMAN (5-212): 1.05e-24: 107: 9.91
+	Hs
		1041692 CUL3_HUMAN (1-768): 0: 951: 100.00		SMU1_HUMAN (8-265): 4.66e-20: 93.3: 9.16
+	Hs
		929445 CUL3_HUMAN (1-768): 0: 951: 100.00		RACK1_HUMAN (7-267): 3.98e-15: 77.1: 13.01
+	Hs
		903207 CUL3_HUMAN (1-768): 0: 951: 100.00		WDR5_HUMAN (3-126): 1.37e-11: 66.8: 10.69
+	Hs
		1042655 CUL3_HUMAN (1-768): 0: 951: 100.00		NLE1_HUMAN (5-78): 5.28e-09: 59.5: 8.00
+	Hs
		1043157 CUL4A_HUMAN (10-768): 0: 791: 38.32		SNR40_HUMAN (34-350): 4.18e-58: 193: 12.65
+	Hs
		1043340 CUL4A_HUMAN (10-768): 0: 791: 38.32		WSB1_HUMAN (55-327): 6.55e-51: 176: 14.09
+	Hs
		1043208 CUL4A_HUMAN (10-768): 0: 791: 38.32		SKI8_HUMAN (117-274): 6.83e-36: 134: 20.89
+	Hs
		1043114 CUL4A_HUMAN (10-768): 0: 791: 38.32		POC1B_HUMAN (3-175): 1.36e-28: 117: 7.48
+	Hs
		1043223 CUL4A_HUMAN (10-768): 0: 791: 38.32		BCAS3_HUMAN (151-271): 1.02e-24: 107: 21.54
+	Hs
		1043385 CUL4B_HUMAN (5-768): 0: 779: 36.77		SMU1_HUMAN (8-265): 4.66e-20: 93.3: 9.16
+	Hs
		1043085 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5B_HUMAN (1-126): 2.08e-12: 69.1: 10.53
+	Hs
		903208 CUL4A_HUMAN (10-768): 0: 791: 38.32		WDR5_HUMAN (3-126): 1.37e-11: 66.8: 10.69
+	Hs
		929446 CUL4B_HUMAN (5-768): 0: 779: 36.77		RACK1_HUMAN (7-267): 3.98e-15: 77.1: 13.01
+	Hs
		1043441 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5B_HUMAN (1-126): 2.08e-12: 69.1: 10.53
+	Hs
		903209 CUL4B_HUMAN (5-768): 0: 779: 36.77		WDR5_HUMAN (3-126): 1.37e-11: 66.8: 10.69
+	Hs
		245601 CUL4B_HUMAN (5-768): 0: 779: 36.77		TBL1X_HUMAN (230-336): 4.34e-10: 63: 15.04