Protein: ISWI
Chromatin-remodeling complex ATPase chain Iswi (EC 3.6.4.-) (CHRAC 140 kDa subunit) (Nucleosome-remodeling factor 140 kDa subunit) (NURF-140) (Protein imitation swi)

Gene: ISWI
Organism: Drosophila melanogaster
Interactions: 146
UniProt ID: Q24368

Gene Ontology (top 5):
GO:0000166 - nucleotide binding
GO:0000785 - chromatin
GO:0003677 - DNA binding
GO:0003682 - chromatin binding
GO:0004386 - helicase activity

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

1173937

Q9V9T4
ATP-dependent chromatin assembly factor large subunit

7

20

Small-scale

0.970

High

1173986

NU301
Nucleosome-remodeling factor subunit NURF301

5

20

Small-scale

0.909

High

1173895

CAF1
Chromatin assembly factor 1 p55 subunit

3

20

Small-scale

0.847

High

68222

A8DYA3
Toutatis, isoform E

2

18

Small-scale

0.754

High

1173933

DPOE3
DNA polymerase epsilon subunit 3

3

4

Small-scale

0.687

High

1173934

CHRC
Chromatin accessibility complex 16kD protein

3

3

Small-scale

0.687

High

1014774

H4
Histone H4

1

16

Small-scale

0.647

High

1173926

DOM
Helicase domino

1

16

Small-scale

0.618

High

1064526

GAGA
Transcription activator GAGA

2

20

Small-scale

0.584

High

1173916

Q8T052
TATA box-binding protein-like 1

2

3

Small-scale

0.584

High

356754

CHDM
Chromodomain-helicase-DNA-binding protein Mi-2 homolog

1

17

High-throughput

0.575

High

426660

HP1
Heterochromatin protein 1

1

20

High-throughput

0.575

High

852930

ACTZ
Actin-related protein 1

1

18

High-throughput

0.575

High

1173914

Q8SY39
ATP-dependent RNA helicase DDX54

1

20

High-throughput

0.575

High

1173927

RUVB2
RuvB-like helicase 2

1

10

High-throughput

0.575

High

1173943

DDX18
Probable ATP-dependent RNA helicase pitchoune

1

20

High-throughput

0.575

High

1173952

RUVB1
RuvB-like helicase 1

1

10

High-throughput

0.575

High

1173957

DDX47
ATP-dependent RNA helicase DDX47

1

20

High-throughput

0.575

High

1173959

LOQS
Protein Loquacious

1

20

High-throughput

0.575

High

1173979

RENT1
Regulator of nonsense transcripts 1 homolog

1

2

High-throughput

0.575

High

616529

ARM
Armadillo segment polarity protein

1

20

Small-scale

0.561

High

305649

IPYR
Inorganic pyrophosphatase

2

0

Small-scale

0.559

High

777354

PARP
Poly [ADP-ribose] polymerase

1

20

Small-scale

0.546

High

1173974

Q9VX35
LD36501p

1

0

High-throughput

0.546

High

1173966

Q9VQI5
Interferon-related developmental regulator 1

2

1

High-throughput

0.504

High

1173898

Q5BI37
LD32807p

1

20

High-throughput

0.492

High

1173628

SEM1A
Semaphorin-1A

1

3

High-throughput

0.489

High

1173897

Q29R10
LD24322p

1

0

High-throughput

0.486

High

56057

A1Z9S6

1

20

Small-scale

0.479

High

120303

M9PD17
Gigas, isoform B

1

3

High-throughput

0.479

High

234471

CTBP
C-terminal-binding protein

1

3

Small-scale

0.479

High

304960

CRY1
Cryptochrome-1

1

1

High-throughput

0.479

High

583633

TOP2
DNA topoisomerase 2

1

11

Small-scale

0.479

High

911450

IMA
Importin subunit alpha

1

20

Small-scale

0.479

High

1019233

P91634
phosphatidylinositol 3-kinase

1

2

High-throughput

0.479

High

1172592

SIMA
Protein similar

1

10

High-throughput

0.479

High

1173297

DIAP2
Death-associated inhibitor of apoptosis 2

1

5

High-throughput

0.479

High

1173893

CP190
Centrosome-associated zinc finger protein Cp190

1

6

Small-scale

0.479

High

1173894

RX21
RNA-binding protein Rsf1

1

20

Small-scale

0.479

High

1173899

Q5U0Y0
Paired amphipathic helix protein Sin3a

1

19

Small-scale

0.479

High

1173910

Q8IQ71
Dikar, isoform C

1

20

High-throughput

0.479

High

1173920

HDAC1
Histone deacetylase HDAC1

1

20

Small-scale

0.479

High

1173922

Q94883
DNA replication-related element factor, isoform A

1

1

Small-scale

0.479

High

1173924

FOXO
Forkhead box protein O

1

20

High-throughput

0.479

High

1173948

IKKB
Inhibitor of nuclear factor kappa-B kinase subunit beta

1

2

High-throughput

0.479

High

1173949

MBDR2
Protein MBD-R2

1

8

Small-scale

0.479

High

1173956

Q9VID9
Uncharacterized protein, isoform B

1

20

Small-scale

0.479

High

1173965

Q9VP57
LD15904p

1

2

Small-scale

0.479

High

1173967

Q9VS55
CTCF

1

6

Small-scale

0.479

High

1173982

Q9VZJ3
GH01794p

1

1

Small-scale

0.479

High

1173988

Q9W1G7
LD21576p

1

3

Small-scale

0.479

High

95294

E1JIM0
Non-specific lethal 1, isoform E

1

0

Small-scale

0.458

High

599449

18C
Histone-like protein 18C

1

0

Small-scale

0.458

High

1173928

M3K7
Mitogen-activated protein kinase kinase kinase 7

1

0

High-throughput

0.458

High

1173939

Q9VAF4
KAT8 regulatory NSL complex subunit 2

1

0

Small-scale

0.458

High

54159

A1Z898
Chromatin assembly factor 1, p105 subunit

1

20

High-throughput

0.445

High

58080

A1ZBE9
Methionine--tRNA ligase, cytoplasmic

1

9

High-throughput

0.445

High

84964

B7Z126
non-specific serine/threonine protein kinase

1

5

High-throughput

0.445

High

608030

TTKB
Protein tramtrack, beta isoform

1

20

High-throughput

0.445

High

669761

RCC1
Regulator of chromosome condensation

1

2

High-throughput

0.445

High

699333

RRP1
Recombination repair protein 1

1

12

High-throughput

0.445

High

704349

SYEP
Bifunctional glutamate/proline--tRNA ligase

1

3

High-throughput

0.445

High

773363

RFC1
Replication factor C subunit 1

1

9

High-throughput

0.445

High

782709

2AAA
Serine/threonine-protein phosphatase PP2A 65 kDa regulatory subunit

1

4

High-throughput

0.445

High

911727

POLO
Serine/threonine-protein kinase polo

1

11

High-throughput

0.445

High

1050881

SSRP1
FACT complex subunit Ssrp1

1

20

High-throughput

0.445

High

1173896

MCM4
DNA replication licensing factor MCM4

1

6

High-throughput

0.445

High

1173901

Q6NP69
GST-containing FLYWCH zinc-finger protein

1

1

High-throughput

0.445

High

1173904

Q7JRJ9
Inner centromere protein, isoform A

1

9

High-throughput

0.445

High

1173907

NHK1
Nucleosomal histone kinase 1

1

7

High-throughput

0.445

High

1173908

MMD4
Modifier of mdg4

1

20

High-throughput

0.445

High

1173909

SLE
Protein slender lobes

1

17

High-throughput

0.445

High

1173911

SPT16
FACT complex subunit spt16

1

7

High-throughput

0.445

High

1173913

Q8MSW0
Isoleucine--tRNA ligase, cytoplasmic

1

5

High-throughput

0.445

High

1173917

GLYR1
Cytokine-like nuclear factor N-PAC

1

13

High-throughput

0.445

High

1173919

Q8T4G5
AFG3 like matrix AAA peptidase subunit 2, isoform A

1

2

High-throughput

0.445

High

1173929

Q9V3V6
26S proteasome regulatory complex subunit p50

1

9

High-throughput

0.445

High

1173930

Q9V405
26S proteasome regulatory subunit 6B

1

3

High-throughput

0.445

High

1173931

API5
Apoptosis inhibitor 5 homolog

1

3

High-throughput

0.445

High

1173932

Q9V434
Asparagine--tRNA ligase, cytoplasmic

1

1

High-throughput

0.445

High

1173935

Q9V455
Importin subunit alpha

1

20

High-throughput

0.445

High

1173938

Q9VAA9
JIL-1 anchoring and stabilizing protein, isoform A

1

20

High-throughput

0.445

High

1173940

Q9VAH7
N-terminal kinase-like protein

1

5

High-throughput

0.445

High

1173945

Q9VDL2
LD40493p

1

20

High-throughput

0.445

High

1173947

Q9VEP0
Regulatory protein zeste

1

1

High-throughput

0.445

High

1173958

Q9VJ12
Acinus, isoform A

1

9

High-throughput

0.445

High

1173960

NFS1
Cysteine desulfurase, mitochondrial

1

2

High-throughput

0.445

High

1173961

CAND1
Cullin-associated NEDD8-dissociated protein 1

1

4

High-throughput

0.445

High

1173970

AIMP2
Probable aminoacyl tRNA synthase complex-interacting multifunctional protein 2

1

1

High-throughput

0.445

High

1173976

Q9VXR5
ATP-binding cassette sub-family F member 2

1

1

High-throughput

0.445

High

1173978

RRP12
RRP12-like protein

1

3

High-throughput

0.445

High

1173981

Q9VZ88
AT07585p

1

20

High-throughput

0.445

High

1173989

NAT10
RNA cytidine acetyltransferase

1

3

High-throughput

0.445

High

1173990

Q9W3D1
Chromatin assembly factor 1, p180 subunit

1

16

High-throughput

0.445

High

1173991

Q9W414
Regulatory particle triple-A ATPase 4

1

3

High-throughput

0.445

High

1173993

SYQ
Probable glutamine--tRNA ligase

1

3

High-throughput

0.445

High

1173942

Q9VCC9
LD23779p

1

20

High-throughput

0.437

High

1173963

ORCO
Odorant receptor coreceptor

1

1

Small-scale

0.437

High

1173964

RHEB
GTP-binding protein Rheb homolog

1

3

High-throughput

0.437

High

1173973

Q9VWJ6
FI03615p

1

4

High-throughput

0.437

High

875202

TCPG
T-complex protein 1 subunit gamma

1

0

High-throughput

0.426

High

909857

PFKA
ATP-dependent 6-phosphofructokinase

1

0

High-throughput

0.426

High

1173903

Q7JNE1
Regulatory protein zeste

1

0

High-throughput

0.426

High

1173912

INDRA
Zinc finger protein indra

1

0

High-throughput

0.426

High

1173923

Q95U38
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial

1

0

High-throughput

0.426

High

1173954

Q9VHG5
Insulator binding factor 1, isoform A

1

0

High-throughput

0.426

High

1173971

Q9VW54
26S proteasome non-ATPase regulatory subunit 2

1

0

High-throughput

0.426

High

1173975

SYRC
Probable arginine--tRNA ligase, cytoplasmic

1

0

High-throughput

0.426

High

1173987

Q9W140
Regulatory protein zeste

1

0

High-throughput

0.426

High

55427

A1Z9E3
Elongation factor Tu

1

4

High-throughput

0.407

High

55768

A1Z9K0
Uncharacterized protein, isoform B

1

2

High-throughput

0.407

High

84797

B7Z0I8
Titin

1

16

High-throughput

0.407

High

263372

PENG
Protein penguin

1

2

High-throughput

0.407

High

852178

COPB
Coatomer subunit beta

1

5

High-throughput

0.407

High

1069490

Q0E8S4
Semaphorin-1A

1

3

High-throughput

0.407

High

1069729

Q0E931
GTP-binding protein 1

1

9

High-throughput

0.407

High

1173900

SARM1
NAD(+) hydrolase sarm1

1

17

High-throughput

0.407

High

1173905

Q7JXU4
Nucleolar GTP-binding protein 2

1

6

High-throughput

0.407

High

1173918

CHM4
Charged multivesicular body protein 4

1

6

High-throughput

0.407

High

1173921

DYLT
Dynein light chain Tctex-type

1

1

High-throughput

0.407

High

1173925

Q95WY3
Nucleolar protein 56

1

8

High-throughput

0.407

High

1173944

Q9VDK7
Signal recognition particle subunit SRP72

1

2

High-throughput

0.407

High

1173946

Q9VEH0
Aluminum tubes, isoform A

1

20

High-throughput

0.407

High

1173950

IPO9
Importin-9

1

5

High-throughput

0.407

High

1173951

Q9VGQ1
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex, mitochondrial

1

5

High-throughput

0.407

High

1173953

Q9VHC0
LD23870p

1

12

High-throughput

0.407

High

1173955

Q9VI53
LD44267p

1

5

High-throughput

0.407

High

1173962

Q9VM57
Septin interacting protein 2, isoform A

1

1

High-throughput

0.407

High

1173968

SRP68
Signal recognition particle subunit SRP68

1

3

High-throughput

0.407

High

1173972

IDH3A
Probable isocitrate dehydrogenase [NAD] subunit alpha, mitochondrial

1

1

High-throughput

0.407

High

1173977

Q9VXY3
Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex

1

5

High-throughput

0.407

High

1173983

Q9VZU8
Alpha-1,3/1,6-mannosyltransferase ALG2

1

1

High-throughput

0.407

High

53118

A1Z7K8
AaRS-interacting multifunctional protein 1

1

0

High-throughput

0.232

Low

118095

M9MSJ7
Uncharacterized protein, isoform C

1

0

High-throughput

0.232

Low

360535

COX2
Cytochrome c oxidase subunit 2

1

0

High-throughput

0.232

Low

1059139

ROP
Protein ROP

1

0

High-throughput

0.232

Low

1173902

BOCKS
LEM domain-containing protein Bocksbeutel

1

0

High-throughput

0.232

Low

1173906

DYM
Dymeclin

1

0

High-throughput

0.232

Low

1173915

Q8SY53
GH11935p

1

0

High-throughput

0.232

Low

1173936

Q9V9Q4
LD43819p

1

0

High-throughput

0.232

Low

1173941

Q9VAW3
glutamine--fructose-6-phosphate transaminase

1

0

High-throughput

0.232

Low

1173969

FRL
Formin-like protein

1

0

High-throughput

0.232

Low

1173980

Q9VYY7
Heterochromatin protein 5, isoform B

1

0

High-throughput

0.232

Low

1173984

Q9W0E4
Aminopeptidase

1

0

High-throughput

0.232

Low

1173985

SAC1
Phosphatidylinositol-3-phosphatase SAC1

1

0

High-throughput

0.232

Low

1173992

Q9XZ53
dolichyl-diphosphooligosaccharide--protein glycotransferase

1

0

High-throughput

0.232

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025