HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: RBBP5 (Q15291)
Retinoblastoma-binding protein 5 (RBBP-5) (Retinoblastoma-binding protein RBQ-3)
Gene: RBBP5

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.60	0.536

Property	Details
Experiments	17041588
Identification Methods	affinity chromatography technology, anti bait coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005654 - nucleoplasm GO:0006974 - DNA damage response
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 538
+	Hs
		1043360 CUL4B_HUMAN (10-759): 0: 927: 82.31		RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00
+	Hs
		1041623 CUL3_HUMAN (32-759): 0: 814: 38.23		RBBP5_HUMAN (1-538): 2.69e-137: 410: 100.00
+	Hs
		1043085 CUL4A_HUMAN (1-759): 0: 963: 100.00		WDR5B_HUMAN (2-225): 9.91e-62: 207: 16.88
+	Hs
		792982 CUL4A_HUMAN (1-759): 0: 963: 100.00		LIS1_HUMAN (104-423): 9.57e-53: 186: 9.65
+	Hs
		1043114 CUL4A_HUMAN (1-759): 0: 963: 100.00		POC1B_HUMAN (2-186): 2.12e-49: 179: 17.74
+	Hs
		1043441 CUL4B_HUMAN (10-759): 0: 927: 82.31		WDR5B_HUMAN (2-225): 9.91e-62: 207: 16.88
+	Hs
		1043469 CUL4B_HUMAN (10-759): 0: 927: 82.31		POC1B_HUMAN (2-186): 2.12e-49: 179: 17.74
+	Hs
		1043157 CUL4A_HUMAN (1-759): 0: 963: 100.00		SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59
+	Hs
		1043064 CUL4A_HUMAN (1-759): 0: 963: 100.00		BRWD3_HUMAN (228-450): 4.8e-15: 80.8: 12.86
+	Hs
		1043124 CUL4A_HUMAN (1-759): 0: 963: 100.00		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		1043385 CUL4B_HUMAN (10-759): 0: 927: 82.31		SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79
+	Hs
		903208 CUL4A_HUMAN (1-759): 0: 963: 100.00		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		1043509 CUL4B_HUMAN (10-759): 0: 927: 82.31		SNR40_HUMAN (229-467): 1.49e-19: 92: 9.59
+	Hs
		1043499 CUL4B_HUMAN (10-759): 0: 927: 82.31		FBXW7_HUMAN (279-521): 2.8e-16: 83.9: 10.56
+	Hs
		1043417 CUL4B_HUMAN (10-759): 0: 927: 82.31		BRWD3_HUMAN (228-450): 4.8e-15: 80.8: 12.86
+	Hs
		1043478 CUL4B_HUMAN (10-759): 0: 927: 82.31		PHIP_HUMAN (227-374): 6.69e-15: 80.4: 13.91
+	Hs
		1042101 CUL3_HUMAN (32-759): 0: 814: 38.23		POC1B_HUMAN (2-186): 2.12e-49: 179: 17.74
+	Hs
		903209 CUL4B_HUMAN (10-759): 0: 927: 82.31		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41
+	Hs
		1041692 CUL3_HUMAN (32-759): 0: 814: 38.23		SMU1_HUMAN (179-320): 3.28e-21: 99: 13.79
+	Hs
		903207 CUL3_HUMAN (32-759): 0: 814: 38.23		WDR5_HUMAN (282-429): 2.1e-09: 61.2: 11.41