Protein: CLA4
Serine/threonine-protein kinase CLA4 (EC 2.7.11.1)

Gene: CLA4
Organism: Saccharomyces cerevisiae S288C
Interactions: 119
UniProt ID: P48562

Gene Ontology (top 5):
GO:0000011 - vacuole inheritance
GO:0000122 - negative regulation of transcription by RNA polymerase II
GO:0000131 - incipient cellular bud site
GO:0000278 - mitotic cell cycle
GO:0000282 - cellular bud site selection

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

618355

CDC42
Cell division control protein 42

12

20

Small-scale

0.978

High

711505

BEM1
Bud emergence protein 1

7

20

Small-scale

0.965

High

874274

NBP2
NAP1-binding protein 2

6

3

Small-scale

0.946

High

542978

CDC24
Cell division control protein 24

4

8

Small-scale

0.913

High

874262

MYO5
Myosin-5

2

20

High-throughput

0.807

High

646465

RAD53
Serine/threonine-protein kinase RAD53

2

14

Small-scale

0.778

High

778999

MYO3
Myosin-3

2

17

Small-scale

0.778

High

763229

PP2C1
Protein phosphatase 2C homolog 1

2

13

High-throughput

0.767

High

587321

ABP1
Actin-binding protein

2

10

High-throughput

0.762

High

746497

BEM3
GTPase-activating protein BEM3

2

5

High-throughput

0.762

High

816034

BOI2
BEM1-interacting protein 2

2

8

High-throughput

0.762

High

676746

GBP2
Serine/arginine

1

4

High-throughput

0.691

High

807678

HRB1
Serine/arginine

1

3

High-throughput

0.691

High

874278

SKM1
Serine/threonine-protein kinase SKM1

1

17

High-throughput

0.691

High

364632

CDK1
Cyclin-dependent kinase 1

1

10

Small-scale

0.665

High

382202

H4
Histone H4

3

5

Small-scale

0.651

High

737330

CDC12
Cell division control protein 12

3

1

Small-scale

0.648

High

656981

BUR1
Serine/threonine-protein kinase BUR1

1

12

Small-scale

0.647

High

660336

STE11
Serine/threonine-protein kinase STE11

1

17

Small-scale

0.647

High

694151

CDC15
Cell division control protein 15

1

17

High-throughput

0.647

High

748870

SWE1
Mitosis inhibitor protein kinase SWE1

1

19

Small-scale

0.647

High

844331

ELP2
Elongator complex protein 2

1

7

High-throughput

0.647

High

804088

GIC1
GTPase-interacting component 1

3

1

High-throughput

0.639

High

874268

GIC2
GTPase-interacting component 2

3

1

High-throughput

0.639

High

393003

HSP82
ATP-dependent molecular chaperone HSP82

1

18

Small-scale

0.618

High

617410

GBB
Guanine nucleotide-binding protein subunit beta

1

6

Small-scale

0.618

High

649643

KCC2
Calcium/calmodulin-dependent protein kinase II

1

3

High-throughput

0.618

High

874253

APJ1
J domain-containing protein APJ1

1

7

High-throughput

0.618

High

874254

ZDS2
Protein ZDS2

3

0

High-throughput

0.612

High

734523

MSB2
Signaling mucin MSB2

2

4

High-throughput

0.590

High

751865

SLA2
Protein SLA2

2

17

High-throughput

0.590

High

811270

RGA1
Rho-type GTPase-activating protein 1

2

6

High-throughput

0.590

High

805556

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

1

2

Small-scale

0.578

High

676145

MAS5
Mitochondrial protein import protein MAS5

1

7

High-throughput

0.575

High

874251

JJJ1
J protein JJJ1

1

8

High-throughput

0.575

High

819202

SSB2
Ribosome-associated molecular chaperone SSB2

2

15

High-throughput

0.552

High

737008

CDC3
Cell division control protein 3

2

2

Small-scale

0.550

High

432629

RL7A
Large ribosomal subunit protein uL30A

1

2

High-throughput

0.536

High

661541

PSA2
Proteasome subunit alpha type-2

1

6

High-throughput

0.536

High

674716

RS2
Small ribosomal subunit protein uS5

1

4

High-throughput

0.536

High

722079

XPO1
Exportin-1

1

12

High-throughput

0.536

High

762984

SPT7
SAGA complex subunit SPT7

1

2

High-throughput

0.536

High

801075

FKS1
1,3-beta-glucan synthase component FKS1

1

1

High-throughput

0.536

High

813294

FHP
Flavohemoprotein

1

1

High-throughput

0.536

High

874259

GCN5
Histone acetyltransferase GCN5

1

5

High-throughput

0.536

High

874276

RL7B
Large ribosomal subunit protein uL30B

1

2

High-throughput

0.536

High

677721

VAC17
vacuole-related protein 17

1

0

Small-scale

0.513

High

874248

PBP1
PAB1-binding protein 1

1

0

High-throughput

0.513

High

531799

RL4A
Large ribosomal subunit protein uL4A

1

3

High-throughput

0.501

High

677216

SPB1
27S pre-rRNA

1

4

Small-scale

0.501

High

750723

PRS6A
26S proteasome regulatory subunit 6A

1

7

Small-scale

0.501

High

751358

DUT
Deoxyuridine 5'-triphosphate nucleotidohydrolase

1

1

High-throughput

0.501

High

796423

TRM7
tRNA

1

4

High-throughput

0.501

High

816497

BUD16
Putative pyridoxal kinase BUD16

1

1

High-throughput

0.501

High

850542

RSC8
Chromatin structure-remodeling complex protein RSC8

1

2

Small-scale

0.501

High

864260

ALY2
Arrestin-related trafficking adapter 3

1

6

Small-scale

0.501

High

865839

EAF6
Chromatin modification-related protein EAF6

1

1

High-throughput

0.501

High

874250

REXO1
RNA exonuclease 1

1

2

High-throughput

0.501

High

874266

RGC1
Regulator of the glycerol channel 1

1

1

High-throughput

0.501

High

874267

MMR1
Mitochondrial MYO2 receptor-related protein 1

1

1

Small-scale

0.501

High

874270

BDF2
Bromodomain-containing factor 2

1

4

High-throughput

0.501

High

874272

SAS10
Something about silencing protein 10

1

2

High-throughput

0.501

High

154191

RL36B
Large ribosomal subunit protein eL36B

1

3

High-throughput

0.489

High

427715

RLA2
Large ribosomal subunit protein P2A

1

2

High-throughput

0.489

High

434174

RL36A
Large ribosomal subunit protein eL36A

1

3

High-throughput

0.489

High

830102

FKS2
1,3-beta-glucan synthase component GSC2

1

1

High-throughput

0.489

High

781112

YKC3
Uncharacterized protein YKL023W

1

0

High-throughput

0.480

High

803992

RSC30
Chromatin structure-remodeling complex protein RSC30

1

0

High-throughput

0.480

High

823329

YJH0
Inactive deaminase YJL070C

1

0

High-throughput

0.480

High

825970

GVP36
Protein GVP36

1

0

High-throughput

0.480

High

874249

RT102
Regulator of Ty1 transposition protein 102

1

0

High-throughput

0.480

High

874257

PTA1
Pre-tRNA-processing protein PTA1

1

0

High-throughput

0.480

High

874264

FUS2
Nuclear fusion protein FUS2

1

0

Small-scale

0.480

High

435212

RS3
Small ribosomal subunit protein uS3

1

4

High-throughput

0.479

High

672915

RRP43
Exosome complex component RRP43

1

1

High-throughput

0.479

High

707580

TF2B
Transcription initiation factor IIB

1

3

High-throughput

0.479

High

747938

SMY2
Protein SMY2

1

1

High-throughput

0.479

High

874243

RS12
Small ribosomal subunit protein eS12

1

2

High-throughput

0.479

High

874244

UBP15
Ubiquitin carboxyl-terminal hydrolase 15

1

10

Small-scale

0.479

High

874246

SUT1
Sterol uptake protein 1

1

2

Small-scale

0.479

High

874255

H3
Histone H3

1

5

High-throughput

0.479

High

874256

CTR9
RNA polymerase-associated protein CTR9

1

6

Small-scale

0.479

High

874275

RIO1
Serine/threonine-protein kinase RIO1

1

4

High-throughput

0.479

High

594453

RPB3
DNA-directed RNA polymerase II subunit RPB3

1

0

High-throughput

0.458

High

798602

PAF1
RNA polymerase II-associated protein 1

1

0

Small-scale

0.458

High

800256

LEO1
RNA polymerase-associated protein LEO1

1

0

Small-scale

0.458

High

864631

NU192
Nucleoporin NUP192

1

0

High-throughput

0.458

High

874247

RTF1
RNA polymerase-associated protein RTF1

1

0

Small-scale

0.458

High

874260

SCC2
Sister chromatid cohesion protein 2

1

0

High-throughput

0.458

High

874269

CDC73
Cell division control protein 73

1

0

Small-scale

0.458

High

575477

GFA1
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

1

3

High-throughput

0.457

High

672257

CDC10
Cell division control protein 10

1

2

Small-scale

0.457

High

737100

CDC11
Cell division control protein 11

1

2

Small-scale

0.457

High

739689

SPT16
FACT complex subunit SPT16

1

4

Small-scale

0.457

High

814123

HPH2
Protein HPH2

1

1

High-throughput

0.457

High

874261

UTP5
U3 small nucleolar RNA-associated protein 5

1

1

Small-scale

0.457

High

874265

COG4
Conserved oligomeric Golgi complex subunit 4

1

1

Small-scale

0.457

High

874273

ATG9
Autophagy-related protein 9

1

1

High-throughput

0.457

High

805678

YHS2
MIP18 family protein YHR122W

1

1

High-throughput

0.457

High

524487

HSP71
Heat shock protein SSA1

1

15

High-throughput

0.445

High

527113

HSP72
Heat shock protein SSA2

1

15

High-throughput

0.445

High

545484

SSB1
Ribosome-associated molecular chaperone SSB1

1

15

High-throughput

0.445

High

741931

HSP7F
Heat shock protein homolog SSE1

1

20

High-throughput

0.445

High

752482

HSP78
Heat shock protein 78, mitochondrial

1

4

High-throughput

0.445

High

804286

SSZ1
Ribosome-associated complex subunit SSZ1

1

8

High-throughput

0.445

High

816296

HSP7E
Heat shock protein SSC3, mitochondrial

1

15

High-throughput

0.445

High

874245

UBP8
Ubiquitin carboxyl-terminal hydrolase 8

1

5

High-throughput

0.445

High

874263

TAF9
SAGA complex/transcription factor TFIID complex subunit TAF9

1

1

High-throughput

0.445

High

747077

SKG6
Protein SKG6

1

0

High-throughput

0.438

High

874271

RBX1
RING-box protein HRT1

1

0

High-throughput

0.438

High

863643

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.426

High

874252

PFD4
Prefoldin subunit 4

1

0

High-throughput

0.426

High

874258

NU100
Nucleoporin NUP100/NSP100

1

1

High-throughput

0.417

High

582488

SEC23
Protein transport protein SEC23

1

0

High-throughput

0.279

Low

736570

RIM1
Single-stranded DNA-binding protein RIM1, mitochondrial

1

0

High-throughput

0.279

Low

798039

YB75
Uncharacterized protein YBR225W

1

0

High-throughput

0.279

Low

758389

UTP11
U3 small nucleolar RNA-associated protein 11

1

0

High-throughput

0.261

Low

874277

ISA2
Iron-sulfur assembly protein 2

1

0

High-throughput

0.261

Low

874279

YB298
Uncharacterized protein YBR298C-A

1

0

High-throughput

0.261

Low


Service provided by Combinatics, Japan

Last updated: 11Aug2025