HitPredict

Interactor 1: CUL4A (Q13619)
Cullin-4A (CUL-4A)
Gene: CUL4A

Interactor 2: FXL15 (Q9H469)
F-box/LRR-repeat protein 15 (F-box only protein 37)
Gene: FBXL15

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	36688959
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005737 - cytoplasm GO:0016567 - protein ubiquitination
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 759 Hs			1 300
+	Hs
		1031192 CUL4A_HUMAN (1-759): 0: 963: 100.00		SKP2_HUMAN (5-293): 1.21e-37: 139: 18.63
+	Hs
		1041197 CUL1_HUMAN (59-759): 0: 745: 30.55		FXL15_HUMAN (1-300): 3.34e-68: 215: 100.00
+	Hs
		1042879 CUL3_HUMAN (32-759): 0: 814: 38.23		KDM2A_HUMAN (24-284): 2.19e-35: 137: 15.88
+	Hs
		1042760 CUL3_HUMAN (32-759): 0: 814: 38.23		FXL17_HUMAN (143-299): 4.94e-19: 89.2: 20.25
+	Hs
		1041256 CUL1_HUMAN (59-759): 0: 745: 30.55		FBXL7_HUMAN (5-272): 8.23e-38: 141: 21.56
+	Hs
		1031190 CUL1_HUMAN (59-759): 0: 745: 30.55		SKP2_HUMAN (5-293): 1.21e-37: 139: 18.63
+	Hs
		1041833 CUL3_HUMAN (32-759): 0: 814: 38.23		FXL19_HUMAN (118-295): 1.13e-10: 64.2: 21.35
+	Hs
		1041146 CUL1_HUMAN (59-759): 0: 745: 30.55		FXL20_HUMAN (5-249): 3.27e-35: 133: 20.87
+	Mm
		1321914 CUL1_MOUSE (59-759): 0: 745: 30.55		FXL20_MOUSE (5-249): 3.37e-35: 133: 20.87
+	Mm
		1376707 CUL1_MOUSE (59-759): 0: 745: 30.55		SKP2_MOUSE (5-268): 6.12e-34: 130: 19.50
+	Hs
		1041088 CUL1_HUMAN (59-759): 0: 745: 30.55		FXL14_HUMAN (29-276): 1.48e-30: 120: 23.55
+	Hs
		1041267 CUL1_HUMAN (59-759): 0: 745: 30.55		FBXL2_HUMAN (5-249): 1.36e-30: 120: 22.05
+	Hs
		1041265 CUL1_HUMAN (59-759): 0: 745: 30.55		FBXL4_HUMAN (17-276): 1.38e-29: 119: 21.40
+	At
		1277334 CUL1_ARATH (57-759): 0: 744: 34.20		SKP2A_ARATH (116-296): 2.32e-25: 105: 22.40
+	Hs
		1041248 CUL1_HUMAN (59-759): 0: 745: 30.55		FXL17_HUMAN (143-299): 4.94e-19: 89.2: 20.25
+	At
		1277345 CUL1_ARATH (57-759): 0: 744: 34.20		EBF1_ARATH (18-218): 2.32e-16: 81.2: 16.75
+	At
		1173680 CUL1_ARATH (57-759): 0: 744: 34.20		EBF2_ARATH (46-218): 1.68e-13: 72.4: 20.44
+	At
		221522 CUL1_ARATH (57-759): 0: 744: 34.20		SKP2B_ARATH (168-276): 6.5e-13: 70: 24.55
+	Hs
		1041100 CUL1_HUMAN (59-759): 0: 745: 30.55		KDM2B_HUMAN (1-166): 8.52e-12: 67.7: 16.83
+	Hs
		1041049 CUL1_HUMAN (59-759): 0: 745: 30.55		FXL19_HUMAN (118-295): 1.13e-10: 64.2: 21.35