HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: ACTBL (Q562R1)
Beta-actin-like protein 2 (Kappa-actin)
Gene: ACTBL2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.60	0.611

Property	Details
Experiments	28225217, 21145461
Identification Methods	proximity labelling technology, affinity chromatography technology, tandem affinity purification
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0070062 - extracellular exosome
Homologous interactions	14

Homologous interactions

Color coding for hit scores

	1 913 Hs			1 376
+	Hs
		891753 CUL4B_HUMAN (1-913): 0: 1184: 100.00		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		915379 CUL4B_HUMAN (1-913): 0: 1184: 100.00		ACTA_HUMAN (1-376): 0: 588: 87.80
+	Hs
		1041722 CUL3_HUMAN (186-913): 0: 853: 37.19		ACTBL_HUMAN (1-376): 0: 616: 100.00
+	Hs
		891752 CUL3_HUMAN (186-913): 0: 853: 37.19		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		915378 CUL3_HUMAN (186-913): 0: 853: 37.19		ACTA_HUMAN (1-376): 0: 588: 87.80
+	Hs
		1041024 CUL1_HUMAN (213-913): 0: 778: 30.16		ACTBL_HUMAN (1-376): 0: 616: 100.00
+	Hs
		891750 CUL1_HUMAN (213-913): 0: 778: 30.16		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		932973 CUL1_HUMAN (213-913): 0: 778: 30.16		ACTS_HUMAN (2-376): 0: 590: 87.47
+	Hs
		915376 CUL1_HUMAN (213-913): 0: 778: 30.16		ACTA_HUMAN (1-376): 0: 588: 87.80
+	Hs
		1041351 CUL2_HUMAN (205-913): 0: 746: 27.53		ACTBL_HUMAN (1-376): 0: 616: 100.00
+	Hs
		891751 CUL2_HUMAN (205-913): 0: 746: 27.53		ACTB_HUMAN (3-376): 0: 596: 91.71
+	Hs
		915377 CUL2_HUMAN (205-913): 0: 746: 27.53		ACTA_HUMAN (1-376): 0: 588: 87.80
+	Hs
		1122467 CUL5_HUMAN (213-913): 0: 610: 26.23		ACTBL_HUMAN (1-376): 0: 616: 100.00
+	Hs
		891952 CUL5_HUMAN (213-913): 0: 610: 26.23		ACTB_HUMAN (3-376): 0: 596: 91.71