HitPredict

Interactor 1: CUL4B (Q13620)
Cullin-4B (CUL-4B)
Gene: CUL4B

Interactor 2: DC2I2 (Q96EX3)
Cytoplasmic dynein 2 intermediate chain 2 (Dynein 2 intermediate chain 2) (WD repeat-containing protein 34)
Gene: DYNC2I2

Species: Homo sapiens

Source: biogrid

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.60	0.479

Property	Details
Experiments	30945288
Identification Methods	affinity chromatography technology
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 913 Hs			1 536
+	Hs
		1043376 CUL4B_HUMAN (1-913): 0: 1184: 100.00		RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16
+	Hs
		245601 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1X_HUMAN (79-424): 4.56e-50: 182: 9.68
+	Hs
		903209 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65
+	Hs
		1043562 CUL4B_HUMAN (1-913): 0: 1184: 100.00		TBL1R_HUMAN (250-526): 3.44e-47: 173: 12.46
+	Hs
		1043441 CUL4B_HUMAN (1-913): 0: 1184: 100.00		WDR5B_HUMAN (26-340): 6.87e-45: 162: 11.64
+	Hs
		997715 CUL4B_HUMAN (1-913): 0: 1184: 100.00		RBBP4_HUMAN (320-526): 6.81e-34: 134: 15.81
+	Hs
		1043469 CUL4B_HUMAN (1-913): 0: 1184: 100.00		POC1B_HUMAN (34-263): 1.8e-23: 105: 11.74
+	Hs
		1043499 CUL4B_HUMAN (1-913): 0: 1184: 100.00		FBXW7_HUMAN (37-294): 3.57e-21: 99.3: 11.63
+	Hs
		1043016 CUL4A_HUMAN (161-913): 0: 955: 81.83		RBBP7_HUMAN (105-535): 1.14e-75: 247: 14.16
+	Hs
		792982 CUL4A_HUMAN (161-913): 0: 955: 81.83		LIS1_HUMAN (262-536): 4.91e-63: 213: 11.63
+	Hs
		903208 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65
+	Hs
		1043085 CUL4A_HUMAN (161-913): 0: 955: 81.83		WDR5B_HUMAN (26-340): 6.87e-45: 162: 11.64
+	Hs
		1033265 CUL3_HUMAN (186-913): 0: 853: 37.19		DC1I2_HUMAN (42-536): 9.49e-73: 245: 19.69
+	Hs
		148070 CUL3_HUMAN (186-913): 0: 853: 37.19		DC1I1_HUMAN (11-536): 2.11e-70: 239: 18.44
+	Hs
		997714 CUL4A_HUMAN (161-913): 0: 955: 81.83		RBBP4_HUMAN (320-526): 6.81e-34: 134: 15.81
+	Hs
		1043114 CUL4A_HUMAN (161-913): 0: 955: 81.83		POC1B_HUMAN (34-263): 1.8e-23: 105: 11.74
+	Hs
		903207 CUL3_HUMAN (186-913): 0: 853: 37.19		WDR5_HUMAN (2-341): 1.79e-50: 177: 11.65
+	Hs
		863425 CUL4A_HUMAN (161-913): 0: 955: 81.83		COPA_HUMAN (3-235): 1.76e-10: 65.8: 5.58
+	Hs
		997713 CUL3_HUMAN (186-913): 0: 853: 37.19		RBBP4_HUMAN (320-526): 6.81e-34: 134: 15.81
+	Hs
		863424 CUL3_HUMAN (186-913): 0: 853: 37.19		COPA_HUMAN (3-235): 1.76e-10: 65.8: 5.58