HitPredict

Interactor 1: ASPP2 (Q13625)
Apoptosis-stimulating of p53 protein 2 (Bcl2-binding protein) (Bbp) (Renal carcinoma antigen NY-REN-51) (Tumor suppressor p53-binding protein 2) (53BP2) (p53-binding protein 2) (p53BP2)
Gene: TP53BP2

Interactor 2: CC85A (Q96PX6)
Coiled-coil domain-containing protein 85A
Gene: CCDC85A

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.62	0.50	0.560

Property	Details
Experiments	32296183, 33961781
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	direct interaction, physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	10

Homologous interactions

Color coding for hit scores

	1 1128 Hs			1 553
+	Hs
		985577 Q05BL1_HUMAN (90-1128): 2.47e-152: 484: 99.90		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		1296359 ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		1299901 BARD1_HUMAN (676-1036): 1.54e-45: 179: 16.83		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		310077 TNKS1_HUMAN (808-1080): 1.68e-44: 178: 12.84		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		1299905 TNKS2_HUMAN (893-1127): 6.78e-43: 172: 14.54		CC85A_HUMAN (1-553): 0: 927: 100.00
+	Hs
		63755 ASPP2_HUMAN (1-1128): 0: 599: 100.00		CC85C_HUMAN (34-268): 7.82e-76: 248: 51.18
+	Hs
		1043663 ASPP2_HUMAN (1-1128): 0: 599: 100.00		CC85B_HUMAN (36-175): 2.73e-51: 176: 50.00
+	Hs
		63793 ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38		CC85C_HUMAN (34-268): 7.82e-76: 248: 51.18
+	Hs
		1079269 ASPP1_HUMAN (1-1128): 4.45e-135: 439: 45.38		CC85B_HUMAN (36-175): 2.73e-51: 176: 50.00
+	Dm
		1372631 Q9W2J2_DROME (126-1123): 2.51e-75: 272: 27.13		Q9VQK1_DROME (71-219): 8.44e-60: 210: 51.68