HitPredict

Interactor 1: PTC1 (Q13635)
Protein patched homolog 1 (PTC) (PTC1)
Gene: PTCH1

Interactor 2: NLRP1 (Q9C000)
NACHT, LRR and PYD domains-containing protein 1 (EC 3.4.-.-) (EC 3.6.4.-) (Caspase recruitment domain-containing protein 7) (Death effector filament-forming ced-4-like apoptosis protein) (Nucleotide-binding domain and caspase recruitment domain) [Cleaved into: NACHT, LRR and PYD domains-containing protein 1, C-terminus (NLRP1-CT); NACHT, LRR and PYD domains-containing protein 1, N-terminus (NLRP1-NT)]
Gene: NLRP1

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.38	0.50	0.437

Property	Details
Experiments	19465923
Identification Methods	anti tag coimmunoprecipitation
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	2

Homologous interactions

Color coding for hit scores

	1 1447 Hs			1 1473
+	Hs
		1044470 PTC1_HUMAN (1-1447): 0: 1579: 100.00		CARD8_HUMAN (1049-1462): 3.91e-137: 434: 42.21
+	Hs
		167827 NPC1_HUMAN (59-1191): 0: 713: 19.74		RINI_HUMAN (676-928): 1.87e-19: 95.2: 22.22