HitPredict

Interactor 1: I10R1 (Q13651)
Interleukin-10 receptor subunit alpha (IL-10 receptor subunit alpha) (IL-10R subunit alpha) (IL-10RA) (CDw210a) (Interleukin-10 receptor subunit 1) (IL-10R subunit 1) (IL-10R1) (CD antigen CD210)
Gene: IL10RA

Interactor 2: FBW1A (Q9Y297)
F-box/WD repeat-containing protein 1A (E3RSIkappaB) (Epididymis tissue protein Li 2a) (F-box and WD repeats protein beta-TrCP) (pIkappaBalpha-E3 receptor subunit)
Gene: BTRC

Species: Homo sapiens

Source: intact

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.72	0.60	0.660

Property	Details
Experiments	32296183, 22087322, unassigned1304
Identification Methods	two hybrid, affinity chromatography technology, anti tag coimmunoprecipitation, validated two hybrid, two hybrid array, two hybrid prey pooling approach
Interaction Type	direct interaction, physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005829 - cytosol
Homologous interactions	4

Homologous interactions

Color coding for hit scores

	1 578 Hs			1 605
+	Hs
		566039 INAR1_HUMAN (25-335): 3.48e-23: 105: 14.93		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		1215853 INLR1_HUMAN (11-308): 1.35e-12: 72.3: 15.92		FBW1A_HUMAN (1-605): 0: 551: 100.00
+	Hs
		566038 INAR1_HUMAN (25-335): 3.48e-23: 105: 14.93		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69
+	Hs
		1215852 INLR1_HUMAN (11-308): 1.35e-12: 72.3: 15.92		FBW1B_HUMAN (96-605): 1.89e-143: 428: 85.69