Protein: MEC3
DNA damage checkpoint control protein MEC3

Gene: MEC3
Organism: Saccharomyces cerevisiae S288C
Interactions: 47
UniProt ID: Q02574

Gene Ontology (top 5):
GO:0000077 - DNA damage checkpoint signaling
GO:0000723 - telomere maintenance
GO:0000722 - telomere maintenance via recombination
GO:0000724 - double-strand break repair via homologous recombination
GO:0000781 - chromosome, telomeric region

Download interactions: TXT   MITAB-2.5

Interaction Interactor Experiments Homologs Category Interaction
Score
Confidence

820012

RAD17
DNA damage checkpoint control protein RAD17

16

0

Small-scale

0.935

High

971774

DDC1
DNA damage checkpoint protein 1

8

0

Small-scale

0.722

High

755796

SET1
Histone-lysine N-methyltransferase, H3 lysine-4 specific

2

0

Small-scale

0.617

High

971769

ATG16
Autophagy protein 16

2

0

High-throughput

0.594

High

688665

MCM10
Minichromosome maintenance protein 10

2

0

Small-scale

0.588

High

697704

TFB1
General transcription and DNA repair factor IIH subunit TFB1

2

0

High-throughput

0.582

High

697309

RAD24
Checkpoint protein RAD24

2

0

Small-scale

0.569

High

512410

SSB1
Ribosome-associated molecular chaperone SSB1

1

1

High-throughput

0.536

High

971772

RIX7
Ribosome biogenesis ATPase RIX7

1

0

High-throughput

0.518

High

859691

LIF1
Ligase-interacting factor 1

1

0

High-throughput

0.513

High

565288

SPO12
Sporulation-specific protein 12

1

0

Small-scale

0.486

High

381476

GAL1
Galactokinase

1

0

High-throughput

0.479

High

560773

BIP
Endoplasmic reticulum chaperone BiP

1

0

High-throughput

0.479

High

633501

MAS5
Mitochondrial protein import protein MAS5

1

0

High-throughput

0.479

High

764583

EXO1
Exodeoxyribonuclease 1

1

0

Small-scale

0.460

High

566219

EST1
Telomere elongation protein EST1

1

0

High-throughput

0.458

High

679872

FUN30
ATP-dependent helicase FUN30

1

0

Small-scale

0.458

High

971773

THI20
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI20

1

1

High-throughput

0.457

High

971775

THI21
Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase THI21

1

1

High-throughput

0.457

High

492175

HSP71
Heat shock protein SSA1

1

1

High-throughput

0.445

High

494750

HSP72
Heat shock protein SSA2

1

1

High-throughput

0.445

High

695339

HSP7F
Heat shock protein homolog SSE1

1

3

High-throughput

0.445

High

696047

HSP79
Heat shock protein homolog SSE2

1

3

High-throughput

0.445

High

769236

SSB2
Ribosome-associated molecular chaperone SSB2

1

1

High-throughput

0.445

High

971768

TFB3
RNA polymerase II transcription factor B subunit 3

1

0

High-throughput

0.438

High

680942

HS104
Heat shock protein 104

1

0

High-throughput

0.426

High

757891

REV7
DNA polymerase zeta processivity subunit

1

0

Small-scale

0.305

High

971770

LIPB
Octanoyltransferase, mitochondrial

2

0

High-throughput

0.295

High

711159

YKK7
Uncharacterized oxidoreductase YKL107W

1

0

High-throughput

0.282

High

715529

SC61G
Protein transport protein SSS1

1

0

High-throughput

0.282

High

971776

YL125
Putative uncharacterized protein YLR125W

1

0

High-throughput

0.282

High

420328

CALM
Calmodulin

1

0

High-throughput

0.269

Low

585364

MYO2
Myosin-2

1

0

High-throughput

0.269

Low

859572

MLC1
Myosin light chain 1

1

0

High-throughput

0.269

Low

536260

RED1
Protein RED1

1

0

Small-scale

0.265

Low

343673

PMG1
Phosphoglycerate mutase 1

1

0

High-throughput

0.261

Low

397612

OTC
Ornithine carbamoyltransferase

1

0

High-throughput

0.261

Low

421683

FAS1
Fatty acid synthase subunit beta

1

0

High-throughput

0.261

Low

498580

METK1
S-adenosylmethionine synthase 1

1

0

High-throughput

0.261

Low

521039

G6PI
Glucose-6-phosphate isomerase

1

0

High-throughput

0.261

Low

556245

VATB
V-type proton ATPase subunit B

1

0

High-throughput

0.261

Low

971777

HSP42
Heat shock protein 42

1

0

High-throughput

0.261

Low

971771

CST9
Chromosome stability protein 9

1

0

Small-scale

0.249

Low

810673

ALY2
Arrestin-related trafficking adapter 3

1

0

High-throughput

0.238

Low

541781

SEC63
Protein translocation protein SEC63

1

0

High-throughput

0.232

Low

761057

TCPZ
T-complex protein 1 subunit zeta

1

0

High-throughput

0.232

Low

810114

PFD1
Prefoldin subunit 1

1

0

High-throughput

0.232

Low


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Last updated: 15 Jul 2024