HitPredict

Interactor 1: LAMC2 (Q13753)
Laminin subunit gamma-2 (Cell-scattering factor 140 kDa subunit) (CSF 140 kDa subunit) (Epiligrin subunit gamma) (Kalinin subunit gamma) (Kalinin/nicein/epiligrin 100 kDa subunit) (Ladsin 140 kDa subunit) (Laminin B2t chain) (Laminin-5 subunit gamma) (Large adhesive scatter factor 140 kDa subunit) (Nicein subunit gamma)
Gene: LAMC2

Interactor 2: FBX2 (Q9UK22)
F-box only protein 2
Gene: FBXO2

Species: Homo sapiens

Source: intact

Category: High-throughput

Confidence: High

Method score	Annotation score	Interaction score
0.47	0.50	0.489

Property	Details
Experiments	33961781
Identification Methods	affinity chromatography technology, anti tag coimmunoprecipitation
Interaction Type	physical association, association

Property	Details
Interacting Pfam domains	-
Common GO terms	-
Homologous interactions	20

Homologous interactions (Top 20)

Color coding for hit scores

	1 1193 Hs			1 296
+	Hs
		1256715 SNED1_HUMAN (252-654): 3.01e-42: 171: 14.68		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1356241 NOTC3_HUMAN (282-746): 4.73e-35: 148: 14.26		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		980571 NOTC2_HUMAN (5-590): 8.2e-31: 134: 11.32		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1045109 LAMB3_HUMAN (8-188): 2.19e-30: 132: 31.94		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1045104 LAMB3_HUMAN (8-188): 2.19e-30: 132: 31.94		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		804367 NOTC1_HUMAN (5-368): 1.5e-15: 84.6: 10.23		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		502885 LAMC1_HUMAN (248-480): 1.36e-14: 81.2: 13.75		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		433202 LAMB1_HUMAN (449-707): 5.77e-14: 79.2: 17.54		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1081784 LAMA4_HUMAN (114-312): 4.34e-13: 76.5: 15.63		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		172717 LAMA5_HUMAN (167-420): 4.63e-12: 73.1: 11.49		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		631086 LAMA1_HUMAN (187-420): 1.72e-11: 71.2: 12.40		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1356246 JAG2_HUMAN (418-747): 2.02e-09: 64.2: 11.59		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		877461 LAMB2_HUMAN (100-284): 2.25e-09: 64.2: 14.83		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1356263 LAMC3_HUMAN (174-423): 3.21e-09: 63.8: 9.88		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		1087533 LAMA3_HUMAN (166-370): 5.92e-09: 63.1: 11.01		FBX2_HUMAN (1-296): 5.13e-147: 416: 100.00
+	Hs
		502876 LAMC1_HUMAN (248-480): 1.36e-14: 81.2: 13.75		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		433191 LAMB1_HUMAN (449-707): 5.77e-14: 79.2: 17.54		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		172709 LAMA5_HUMAN (167-420): 4.63e-12: 73.1: 11.49		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		877456 LAMB2_HUMAN (100-284): 2.25e-09: 64.2: 14.83		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81
+	Hs
		1087532 LAMA3_HUMAN (166-370): 5.92e-09: 63.1: 11.01		FBX6_HUMAN (40-296): 2.4e-133: 381: 49.81