HitPredict

Interactor 1: APR (Q13794)
Phorbol-12-myristate-13-acetate-induced protein 1 (PMA-induced protein 1) (Immediate-early-response protein APR) (Protein Noxa)
Gene: PMAIP1

Interactor 2: IRF3 (Q14653)
Interferon regulatory factor 3 (IRF-3)
Gene: IRF3

Species: Homo sapiens

Source: innatedb

Category: Small-scale

Confidence: High

Method score	Annotation score	Interaction score
0.56	0.60	0.584

Property	Details
Experiments	19152337, 16832344
Identification Methods	anti tag coimmunoprecipitation, electrophoretic mobility supershift assay
Interaction Type	physical association

Property	Details
Interacting Pfam domains	-
Common GO terms	GO:0005634 - nucleus GO:0005739 - mitochondrion GO:0005829 - cytosol GO:0006915 - apoptotic process GO:0006974 - DNA damage response and 1 others more... GO:0051607 - defense response to virus
Homologous interactions	1

Homologous interactions

Color coding for hit scores

	1 54 Hs			1 427
+	Hs
		1045345 APR_HUMAN (1-54): 2.84e-26: 91.7: 100.00		IRF7_HUMAN (4-383): 1.71e-105: 323: 26.03